Clinical trials: Continuous Renal Replacement Therapy (CRRT)
Hemodiafiltration, Sepsis
Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)
Study: Open label, non-randomized, observational, descriptive and prospective pharmacokinetic. Patients: sepsis patients undergoing continuous renal replacement therapy (CRRT) and admitted at the Intensive care unit of Bellvitge…
- Conditions
- Hemodiafiltration, Sepsis, Acute Kidney Injury
- Trial name
- NCT04033029
- Testing
- Continuous venovenous hemodiafiltration with high adsorption membrane (oXiris®), Antibiotics
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari de Bellvitge
Critically Ill, Acute Renal Failure
2012_PharmacoCRRT-study:Pharmacokinetics of Anti-infectives in Critically Ill Patients in Need of Continuous Renal Replacement Therapy (CRRT)
The main purpose of the study is to examine if changes in pharmacokinetics of important antiinfectives in Critically Ill patients in need of continuous renal replacement therapy (CRRT), causes inadequate concentrations in plasma.
- Conditions
- Critically Ill, Acute Renal Failure, Acute Kidney Injury
- Trial name
- PharmacoCRRT (NCT01582360)
- Where
- Norway
- Volunteers
- 640 people
- Sponsor
- Oslo University Hospital
Acute Kidney Injury
Discontinuing CRRT in Patients with Acute Kidney Injury
In this study, investigators are going to test whether a standardize approach to discontinuation of Continuous Renal Replacement Therapy (CRRT) using a set of criteria improves outcomes.
- Trial name
- DC-CRRT (NCT04898595)
- Testing
- Discontinuation of CRRT
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- West Virginia University
Burns, Sepsis
The Impact of Continuous Renal Replacement Therapy on the Outcomes of Burn Patients With Early Phase of Sepsis
The purpose of this study is to determine if early application of CRRT will result in an improvement of clinical outcomes of burn patients during the early phase of sepsis
- Trial name
- CRRT (NCT01501097)
- Testing
- Continuous Renal Replacement Therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southwest Hospital, China
Severe Sepsis
The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis
The study will evaluate the benefit of early initiation of CRRT in the initial phase of severe sepsis in patients admitted to the ICU. Primary evaluated end-point is 28-day mortality.
- Trial name
- NCT03141112
- Testing
- renal replacement therapy
- Volunteers
- 200 people
- Sponsor
- Radovan Uvizl
Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT)
Clinical Evaluation of Use of Prismocitrate 18 in Patients Undergoing Acute Continuous Renal Replacement Therapy (CRRT)
The purpose of this research is to determine if an investigational new drug solution called Prismocitrate 18 lengthens extracorporeal circuit life in patients treated with continuous renal replacement therapy (CRRT).
- Conditions
- Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury
- Trial name
- NCT02860130
- Testing
- Prismocitrate 18, No Anticoagulation
- Where
- 12 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- Vantive Health LLC
Intra-Abdominal Hypertension, Critical Illness
Intra-Abdominal Pressure Changes During Continuous Renal Replacement Therapy in Critically Ill Patients
This prospective observational study will evaluate changes in intra-abdominal pressure in critically ill adult patients receiving continuous renal replacement therapy in the intensive care unit.
- Conditions
- Intra-Abdominal Hypertension, Critical Illness, Continuous Renal Replacement Therapy
- Trial name
- NCT07823387
- Testing
- Intravesical Intra-abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Sepsis, Septic Shock
Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury
Septic patients with acute kidney injury (SA-AKI) requiring continuous renal replacement therapies (CRRT) present high mortality due to systemic inflammatory response, cytokine liberation, and finally multiorgan dysfunction.
- Conditions
- Sepsis, Septic Shock, Acute Kidney Injury
- Trial name
- NCT01790620
- Testing
- CVVHD, CVVH
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Universitari de Bellvitge
Acute Renal Failure
Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF).
This study seeks to determine if increasing the dose of continuous renal replacement therapy (CRRT) reduces 90-day all cause mortality in Intensive Care Unit (ICU) patients with severe acute renal failure (ARF).
- Trial name
- NCT00221013
- Testing
- "augmented" CRRT regimen
- Where
- Australia
- Volunteers
- 1,508 people
- Sponsor
- The George Institute
Liver Failure, Acute Kidney Injury
Continuous Renal Replacement Therapy (CRRT) in Surgery Room During Orthotopic Liver Transplantation (OLT)
The study is interventional, non-pharmacological, single-center. The aim of this study is to test the possible added value of CRRT in the surgery room during liver transplantation, compared to the investigators center current…
- Conditions
- Liver Failure, Acute Kidney Injury, Kidney Disease, Chronic
- Trial name
- CRRT-OLT (NCT06844435)
- Testing
- continuous renal replacement therapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Kidney Injury
Changes of Renal Resistive Index in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy.
The aim of the study is to determine whether there is a correlation between changes in the renal resistive index and the restoration of kidney function in critically ill patients undergoing continuous renal replacement therapy.
- Trial name
- NCT06174610
- Testing
- Measurement of Renal Resistive Index
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu
AKI - Acute Kidney Injury, Critical Illness
Continuous Renal Replacement Therapy, Impact on Intensive Care Unit Length of Stay
This large national cohort study, including over 500,000 patients, where around 5% are treated with continuous renal replacement therapy (CRRT) , aims to evaluate the association between time to initiation of CRRT and intensive…
- Trial name
- CIILOS (NCT07586059)
- Testing
- continuous renal replacement therapy
- Volunteers
- 500,000 people
- Sponsor
- Karolinska Institutet
Acute Kidney Injury
Investigating Different Anticoagulants for Renal Replacement Therapy
The aim of this study is to evaluate the effect of regional citrate anticoagulation within the scope of continuous renal replacement (CRRT) in critically ill patients with acute kidney injury (AKI) on filter life span and 90-day…
- Trial name
- RICH (NCT02669589)
- Testing
- Heparin, Citrate
- Where
- 31 sites in Germany
- Volunteers
- 638 people
- Sponsor
- University Hospital Muenster