Clinical trials: Contraceptive Devices
Dysmenorrhea
Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea
The primary hypothesis is that continuous administration of an OCP (CCOCP regimen) will result in more pain relief than a traditional 21/7 administration in primary dysmenorrhea (PD) patients.
- Trial name
- Dysmenorrhea (NCT00517556)
- Testing
- CCOCP, Traditional OCP
- Where
- Croatia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Overweight, Obesity
A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
The purpose of this clinical study is to find out if NNC0662-0419 is safe and effective to be taken together with other medicines, like birth control pills, and emptying of the stomach in women not able to become pregnant living…
- Trial name
- NCT07525791
- Testing
- NNC0662-0419, Oral contraceptive, Acetaminophen
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
Effect of PF-06651600 on the Pharmacokinetics of Oral Contraceptive Steroids
This is a Phase 1, randomized, 2 way crossover, open-label study of the effect of multiple-dose PF 06651600 on single-dose oral contraceptive (OC) pharmacokinetics (PK) in healthy female subjects.
- Trial name
- NCT04018274
- Testing
- PF-06651600, Ethinyl estradiol (EE) and levonorgestrel(LN)
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pfizer
Contraception, Contraceptive Behavior
Patient-Centered Support for Contraceptive Decision-Making
The investigators have designed a tablet-based decision support tool to help women learn more about their birth control options and support them in choosing a method they are happy with.
- Trial name
- NCT02078713
- Testing
- Contraceptive Decision Support Tool
- Where
- 4 sites in United States
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Prenatal Care Late, Contraceptive Usage
Community-based Provision of Urine Pregnancy Tests as Linkage to Reproductive Health Services
Kenyan families experience persistently high rates of maternal and neonatal mortality, which disproportionately affects women with low income and education and those who live far from health services.
- Conditions
- Prenatal Care Late, Contraceptive Usage, Pregnancy Complication
- Trial name
- NCT03626597
- Testing
- Urine Pregnancy Test, CHV-based post-test counseling & referral, Phone-based post-test counseling & referral
- Where
- Kenya
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Indiana University
Healthy Participants
A Study to Investigate the Interaction of BMS-986322 and a Combined Oral Hormonal Contraceptive (Ethinyl Estradiol [EE]/Norethindrone [NET]) in Healthy Female Participants
The purpose of this study is to evaluate the effect of multiple doses of BMS-986322 on the pharmacokinetics (PK) of Loestrin components in healthy female participants.
- Trial name
- NCT05579574
- Testing
- BMS-986322, Loestrin
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Contraception
A Study Comparing Implant Provision by Community Health Extension Workers With Nurses and Midwives in Nigeria
This proposed study, to be run by Marie Stopes International Organisation Nigeria (MSION) will investigate whether Community Health Extension Workers (CHEWs) in Nigeria can insert and remove contraceptive implants to the same…
- Trial name
- NCT03088722
- Testing
- Training CHEWs to provide contraceptive implants
- Volunteers
- 7,903 people, healthy volunteers welcome
- Sponsor
- Marie Stopes International
Contraception
Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel
This is a research study of a new experimental vaginal gel that helps in vaginal pH regulation and results in immobilization of spermatozoa by maintaining the normally low vaginal pH, even in the presence of semen.
- Trial name
- NCT01306331
- Testing
- Conceptrol, Amphora
- Where
- 52 sites in United States, Russia
- Volunteers
- 3,389 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Other Disorders of Bone Development and Growth
Assessing the Impact of Contraceptives on Bone Health Using 41Ca
This preclinical randomized crossover study will examine the effects of oral versus non-oral contraceptive therapy on bone turnover in young exercising women.
- Trial name
- NCT02367846
- Testing
- Combined Oral Contraceptive (COC), Contraceptive Vaginal Ring (CVR)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Penn State University
NASH - Nonalcoholic Steatohepatitis
Pemvidutide (ALT-801) DDI Study in Healthy Volunteers
This is a Phase 1, open-label, drug-drug interaction (DDI) study of pemvidutide (ALT-801) under steady state conditions on concomitantly administered medications in healthy subjects.
- Trial name
- NCT04972396
- Testing
- Pemvidutide, Metformin, Atorvastatin
- Where
- 2 sites in Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Altimmune, Inc.
Contraceptive Usage
Essure Transvaginal Ultrasound (TVU) Study
The Essure procedure, FDA approved since 2002 and CE Mark approved since 2001, is the first permanent birth control method that can be performed in the comfort of a physician's office without hormones, cutting, burning or the…
- Trial name
- NCT01327105
- Testing
- TVU
- Where
- 21 sites in United States, Canada and 2 more
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Contraceptive Counselling: Impact on Awareness of the Risk of Unwanted Pregnancy and on the Appeal of Contraception
The hypothesis of this study is that the generalisation of minimal contraceptive advice in general medical consultations among women of childbearing age in Reunion Island who do not use contraception but who have sexual relations…
- Trial name
- CMC (NCT05676762)
- Where
- Reunion
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Partial Epilepsy
Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined Oral Contraceptive
The purpose of this study is to investigate whether multiple-dose administration of eslicarbazepine acetate (ESL, BIA 2-093) 800 mg once-daily (QD) affects the pharmacokinetics and tolerability of the components of a combined…
- Trial name
- NCT00898560
- Testing
- eslicarbazepine acetate and Microginon®, Microginon®
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Contraception, Immigrant
Implementing Best Practice Postpartum Contraceptive Services Through a Quality Improvement Initiative
Immigrant women in Europe has reported lower use of effective contraception, higher risks of multiple births, and unintended pregnancies compared to native-born women.
- Conditions
- Contraception, Immigrant, Post Partum
- Trial name
- IMPROVE-it (NCT05521646)
- Testing
- Quality Improvement Collaborative
- Where
- Sweden
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Contraception, Female Contraception
A Study to Evaluate the Efficacy and Safety of DR-102 for the Prevention of Pregnancy
This is an open-label, single treatment study. All subjects will receive 12 months of oral contraceptive therapy with DR-102. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT01178125
- Testing
- DR-102
- Where
- 62 sites in United States, Israel
- Volunteers
- 2,858 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Pregnancy, Chlamydia
Using the Healthcare Visit to Improve Contraceptive Use
Consistent and correct use of an effective contraceptive method is a primary determinant in preventing pregnancy. Unfortunately, only a minority of healthcare providers adequately address women's contraceptive needs.
- Trial name
- NCT00140296
- Testing
- Contraceptive counseling
- Where
- United States
- Volunteers
- 747 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Chronic Hepatitis B
A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults
This study is designed to assess 1) the effect of multiple doses of itraconazole (CYP3A4 inhibitor), rifampin (CYP3A4 inducer), and esomeprazole (pH modifier) on the pharmacokinetics of a single oral dose of ABI-H2158, and 2) the…
- Trial name
- NCT04142762
- Testing
- ABI-H2158, Itraconazole, Rifampin
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assembly Biosciences
Contraception, Contraception Behavior
Contraception for Solid Organ Transplant Patients: Utilizing Social Media
The purpose of this study is to use an electronic survey to explore Solid Organ Transplant patients' contraceptive knowledge and counseling.
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Reproductive Health
- Trial name
- NCT03979950
- Testing
- Survey
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Recovery, Oral Contraceptive Use
The Influence of Oral Contraceptive Use on Muscle Recovery
There is still no one who has studied how oral contraceptive use affects recovery in trained women after repeated high-intensity workouts. Consequently, a well-controlled study is needed.
- Trial name
- OC-R (NCT04564300)
- Testing
- Training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Drug Interactions, Contraception
A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) in Healthy Women.
The purpose of the study is to assess the effect of folic acid administration on the blood level and the breakdown products of oral contraceptive (OC) [250 mcg NGM/35 mcg EE] tablets.
- Conditions
- Drug Interactions, Contraception, Pharmacokinetics
- Trial name
- NCT00709332
- Testing
- Norgestimate; Ethinyl Estradiol; Folic acid
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.