Clinical trials: Contraceptive Devices
Female Contraception, Contraception
Bioequivalence Study of the Oral Contraceptive Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.
The purpose of the study is to determine the bioequivalence of NGM and EE in 2 formulations of 250 mcg NGM/35 mcg EE, 1 without folic acid and 1 containing 400 mcg folic acid.
- Conditions
- Female Contraception, Contraception, Therapeutic Equivalency, Pharmacokinetics
- Trial name
- NCT00709189
- Testing
- Norgestimate/Ehinyl Estradiol; Folic acid.
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception
Prospective Controlled Cohort Study on the Safety of a Monophasic Oral Contraceptive Containing Nomegestrol Acetate (2.5mg) and 17ß-estradiol (1.5mg)
This study compares the risks of short- and long-term use of NOMAC-E2 (containing a fixed dose of nomegestrol acetate and estradiol) compared with levonorgestrel-containing combined oral contraceptives (COC-LNG) in a study…
- Trial name
- PRO-E2 (NCT01650168)
- Where
- Germany
- Volunteers
- 101,498 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Contraception
Observational Study on Contraception With Essure in France
Using a very broad survey, the objective is to confirm the effectiveness of the Essure method, and to obtain more information on the conditions of use as well as on the methods used during the 3-month check-up, as well as the…
- Trial name
- SUCCES II (NCT02510443)
- Testing
- ESS305 (Essure, BAY1454032)
- Where
- France
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Bayer
Ovulation Inhibition
Ovulation Inhibition of Two 4-phasic Oral Contraceptive Regimens
The aim of the study is to investigate the ovulation inhibition of two 4-phasic oral contraceptive regimens.
- Trial name
- NCT00805415
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), EV/DNG (SH T00658L)
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Bayer
Supportive Care
The Effect of Transtheoretical Model-Based Motivational Interviewing on Postpartum Contraception
The goal of this clinical trial is to evaluate the effect of transtheoretical model-based antenatal and postnatal motivational interviewing on contraceptive self-efficacy, contraceptive attitude, and postpartum contraception use.
- Trial name
- NCT06521138
- Testing
- Motivational interviewing group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gazi University
HIV Testing, Contraceptive Usage
Adolescent Wellness Visits in Tanzania
This study evaluates the impact of clinic-based 'Adolescent Wellness Visits' (AWVs) coordinated with primary schools that offer a package of evidence-based adolescent-friendly preventative services on HIV testing uptake in…
- Trial name
- VITAA (NCT05306938)
- Testing
- Adolescent Wellness Visit
- Where
- Tanzania
- Volunteers
- 1,095 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Polycystic Ovary Syndrome
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
The polycystic ovary syndrome is the most common endocrinopathy in reproductive age women. The pathophysiology of this syndrome remains unclear, but there are evidences that a decreased in insulin sensitivity may be related in…
- Trial name
- NCT00988078
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Residual Drug Amount of EE and LNG
A Postmarketing Open-Label Study to Assess Residual Levonorgestrel (LNG) and Ethinyl Estradiol (EE) Content of TWIRLA® (Levonorgestrel and Ethinyl Estradiol) Transdermal System
The objective of this open-label study was to assess residual EE and LNG content on used Twirla® TDSs, packaging, and the skin surface at the application site after 7 full days of wear and the estimate EE and LNG loaded on…
- Trial name
- NCT07739589
- Testing
- Twirla® (Levonorgestrel/Ethinyl Estradiol) Transdermal System
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Diabetes Mellitus, Type 2
A Study of the Effect of Dulaglutide on How the Body Handles Oral Contraceptive in Healthy Female Participants
The purpose of this study is to look at how the body processes oral contraceptive (OC), using Ortho-Cyclen, as a commonly prescribed combination oral contraceptive in healthy female participants, and the effect of dulaglutide on…
- Trial name
- NCT01458210
- Testing
- Ortho-Cyclen, Dulaglutide
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Drug Interactions
A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen
The primary objective of this study is to evaluate the effect of multiple doses of a uridine diphosphate glucuronosyltransferases (UGT)-inducing oral contraceptive (OC) regimen (ethinyl estradiol and levonorgestrel) on the PK of…
- Trial name
- NCT03324685
- Testing
- BIIB074, OC (ethinyl estradiol and levonorgestrel)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biogen
Contraception
A Study to Investigate the Contraceptive Efficacy and Safety of a Subdermal Etonogestrel Implant (Implanon®)(P06473)(COMPLETED)
The primary purpose of this study is to investigate the contraceptive efficacy, safety and acceptability of Organon's subdermal etonogestrel implant in healthy female volunteers in various countries in order to obtain…
- Trial name
- NCT00725413
- Testing
- etonogestrel implant (Implanon)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Menstrual Cycle, Oral Contraceptive Use
Effects of the Menstrual Cycle and Oral Contraceptive Use on Health and Performance in Athletes
A review of the sports medicine literature reveals a clear underrepresentation of female athletes in research. In the current era of precision medicine, increasing attention has been directed toward the regulatory roles of…
- Conditions
- Menstrual Cycle, Oral Contraceptive Use, Athlete
- Trial name
- Flow2Perform (NCT07591818)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Contraception, Female Contraception
A Study of Efficacy and Safety With the Transdermal Contraceptive System Versus Triphasil.
The purpose of the study was to compare the contraceptive efficacy and safety of the transdermal patch to Triphasil.
- Trial name
- NCT00236795
- Testing
- norelgestromin + ethinyl estradiol; triphasil.
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Other Cardiovascular Diseases of Mother, Postpartum
Interactive Mobile Health Intervention to Improve Early Postpartum Modern Contraceptive Method Uptake
The main aim of this study is to determine effectiveness of mobile health intervention to improve early postpartum modern contraceptive service uptake among postpartum women in Dessie and Kombolcha town zones, North east…
- Trial name
- EPPMC (NCT05666037)
- Testing
- Mobile health intervention(mHealth)
- Where
- Ethiopia
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Wollo University
Pregnancy, Sexually Transmitted Diseases
Increased Access to Emergency Contraceptive Pills
This study will evaluate the effect of easy access to emergency contraceptive pills (ECPs) on the rates of pregnancy and sexually transmitted infections (STIs).
- Trial name
- NCT00060463
- Testing
- Increased access to emergency contraceptive pills
- Where
- 2 sites in United States
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Contraceptive Usage, Coagulation
How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills
A randomized study is to learn more about how a supplement called DHEA (dehydroepiandrosterone) affects clotting factors in women taking combined oral contraceptive pills.
- Trial name
- COC+DHEA (NCT03418363)
- Testing
- DHEA Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Study to Investigate Compliance With the Oral Contraceptive SH T00186D in a Flexible Extended Regimen Supported by a Dispenser With a Reminder Function
The objective of the study is to evaluate the effect of the dispenser's buzzer function on compliance with daily tablet intake of an ethinyl estradiol (EE) + drospirenone (DRSP) containing oral contraceptive (OC) in a flexible…
- Trial name
- NCT01257984
- Testing
- BAY86-5300
- Where
- 43 sites in France, Germany and 3 more
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Bayer
Infection, Human Immunodeficiency Virus, HIV Infections
A Study to Evaluate the Pharmacokinetics of an Oral Contraceptive When Co-administered With GSK2248761 in Healthy Adult Female Subjects.
This study is a two-period, double-blind study in healthy adult female subjects. Each subject will participate in an oral contraceptive Run-in period prior to the treatment periods.
- Trial name
- NCT01195974
- Testing
- YASMIN, GSK2248761
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Contraception
Lower Dose Depo Provera® Contraceptive Injection
This is a randomized, partially-blinded, multi-center, parallel-group study to evaluate and compare the PD and PK of MPA after a single SC injection of either 45 mg/0.3 mL, 75 mg/0.5 mL or 105 mg/0.7 mL of Depo-Provera CI, and…
- Trial name
- NCT02732418
- Testing
- Depo-Provera CI, Depo-subQ 104
- Where
- 3 sites in Brazil, Chile and 1 more
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraception
Metabolism Study to Investigate the Impact of a Sequential Oral Contraceptive
The purpose of this study is to confirm the safety of SH T00658ID with regard to plasma lipids, hemostatic variables, and carbohydrate metabolism.
- Trial name
- NCT00185224
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), SH D00264A (Triquilar)
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bayer