Clinical trials: Contraceptive Devices
Complications; Contraceptive, Female Lactation
Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant
A highly effective single rod contraceptive implant is now available for use in the US. Delays in the insertion of the device until later in the postpartum period may negatively impact initiation rates.
- Trial name
- NCT00847587
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Utah
Family Planning, Contraception
Evaluation of Dynamics of Contraceptive Use, Discontinuation and Method Switching in Migori and Kitui Counties, Kenya
Kenya has made tremendous strides in improving contraceptive prevalence rate for the last 20 years, however the rate of contraceptive discontinuation as remained almost constant at 1 out of 3 women using a family planning method.
- Trial name
- NCT03973593
- Testing
- Enhancing contraceptive counseling on method continuation and switching
- Where
- 2 sites in Kenya
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Hepatitis C
Drug Interaction Study of an OCP (Norethindrone (ND) Acetate and Ethinyl Estradiol (EE))With a Combination of Daclatasvir (DCV) Asunaprevir (ASV) and BMS-791325
The purpose of this study is to assess the effect of DCV/ASV/BMS-791325 fixed dose combination (FDC) + 75mg BMS-791325 on the Pharmacokinetics (PK) of the oral contraceptive agent.
- Trial name
- NCT02103569
- Testing
- FDC of Daclatasvir, Asunaprevir and BMS-791325, FDC of Norethindrone and Ethinyl Estradiol, BMS-791325
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Menstrual Problem
New Treatments for Troublesome Bleeding in Implanon Users
Most Implanon users experience a reduction in the frequency and volume of menstrual bleeding, but a substantial minority experience unpredictable and frequent and/or prolonged episodes of bleeding.
- Trial name
- NCT01384331
- Testing
- Marvelon
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Family Planning Association New South Wales
Contraception
Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use
This study is designed to assess whether consumers select and use norgestrel 0.075 mg, a progestin only pill for contraception, in a manner consistent with the OTC package directions in an Over-the-Counter (OTC)-like setting.
- Trial name
- ACCESS (NCT04112095)
- Testing
- Norgestrel 0.075 mg tablets
- Where
- 38 sites in United States
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Women at Risk for Pregnancy
A PK Study Comparing VeraCept vs. ParaGard Intrauterine Devices (IUDs)
to Assess the Pharmacokinetic Properties of VeraCept® Intrauterine Contraceptive vs ParaGard® in Healthy, Post- Menarcheal Women
- Trial name
- IUD (NCT03785366)
- Testing
- VeraCept, ParaGard
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.
Breast Feeding, Contraception
Breastfeeding and Oral Contraceptives: a Randomized, Controlled Trial
Objectives To clarify the relationship between postpartum (2 weeks) use of progestin-only vs. combined oral contraceptive pills and the outcomes of breastfeeding continuation, infant growth, contraceptive method continuation, and…
- Trial name
- NCT01465022
- Testing
- Combined estrogen-progestin pill, Progestin-only pill
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Unintended Pregnancy, Contraception
Contraceptive Choice Center
The Contraceptive Choice Center will use an innovative-model of contraceptive care which was developed as a part of the Contraceptive CHOICE Project (CHOICE).
- Conditions
- Unintended Pregnancy, Contraception, Family Planning
- Trial name
- C3 (NCT02633631)
- Where
- United States
- Volunteers
- 2,664 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Urinary Tract Infections
Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years
The objective of this study is to determine the magnitude and clinical relevance of a potential drug-drug interaction of GSK3882347 with midazolam (MDZ) in healthy participants.
- Trial name
- NCT05760261
- Testing
- Midazolam, GSK3882347
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Males, Male Contraceptive
Oral T7 Oral Testosterone in Man
The purpose of this study is to test how the body absorbs and processes new forms of oral testosterone. Information gained during the study may help develop better forms of testosterone therapy in the future.
- Trial name
- Oral T7 (NCT00842751)
- Testing
- First Intervention (7 days), First Washout (7 days), Second Intervention (7 days)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraceptive Usage
Multilevel Family Planning Intervention
This study seeks to develop and evaluate a multi-level intervention to satisfy couples' unmet need for family planning in rural Uganda.
- Trial name
- NCT04262882
- Testing
- Multilevel Family Planning Intervention, Time and attention matched control
- Where
- 2 sites in Uganda
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
IUD
Trans Caesarean Intra Uterine Contraceptive Device Insertion Versus Conventional Postpartum 6 Weeks Insertion
To compare immediate post-placental intrauterine contraceptive device insertion versus conventional placement at 6 weeks interval (often referred to as delayed or interval insertion) as regard to:- 1. Patient satisfaction. 2.
- Trial name
- IUDinsertion (NCT06023849)
- Testing
- IUD insertion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Contraception
A Multi-center, Open-label, Randomized, Parallel Group Study to Evaluate Pharmacokinetic Profile, Effects on the Mechanisms of Contraceptive Efficacy and Safety of Two Progestin-only Patches Containing Different Doses of Levonorgestrel (LNG)
WHAT IS THE STUDY PRODUCT? The study product is a contraceptive patch, which has the study drug on the patch. The patch is applied directly to the skin and it contains Levonorgestrel (LNG) in a time-release form.
- Trial name
- CCN009 (NCT01166412)
- Testing
- levonorgestrel patch with BMI 32 kg/m2 to <40 kg/m2, levonorgestrel patch with BMI <32 kg/m2
- Where
- 6 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Premier Research
Female Contraception
Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive
Participants in the study will use mifepristone 50 mg once-a-week for one year as a contraceptive. With this, we want to confirm that the chances of getting pregnant while using this contraceptive are very small.
- Trial name
- WOMEN&More (NCT06394999)
- Testing
- Mifepristone 50 mg
- Where
- 14 sites in Netherlands
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Contraceptive Usage, Bleeding Due to Intrauterine Contraceptive Device
Acceptability and Continuation Rate of Implanon in a Brazilian Public Sector
The main side-effect of Implanon is the changes induces in bleeding patterns including amenorrhea, infrequent to irregular bleeding and frequent and prolonged bleeding; without any previous symptom and it was characterized as…
- Trial name
- NCT01392157
- Testing
- copper-releasing intrauterine device, ENG-releasing implant, LNG-releasing intrauterine system
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Ultrasound Finding: Ovulation Inhibition, Ovarian Activities, Cervical Mucus
"Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition
The goal of this clinical trial is to learn if Estetrol/Drospirenone inhibit ovulation in quick-starting method. It will also learn about the safety of Estetrol/Drospirenone. The main questions it aims to answer are: 1.
- Conditions
- Ultrasound Finding: Ovulation Inhibition, Ovarian Activities, Cervical Mucus, Serum Hormonal Profile
- Trial name
- NCT06396221
- Testing
- Estetrol 15 mg/Drospirenone 3 mg (24/4), Ethinylestradiol (EE) 20 mcg/Gestodene 75 mcg (21/7)
- Where
- Thailand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Contraception
Contraceptive Effectiveness of Sino-implant (II) in China
A cohort study to Evaluate the contraceptive effectiveness of Sino-implant (II) during the 3rd and 4th years of use in Chinese women
- Trial name
- NCT01936454
- Where
- 5 sites in China
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- FHI 360
Menorrhagia
A New Treatment Option for Heavy Menstrual Bleeding
Women with measured menstrual bleeding >80ml per cycle and no contraindications to combined oral contraceptive use will be assigned to an oestradiol/nomegestrol acetate oral contraceptive for 3 cycles during which they will…
- Trial name
- NCT01715025
- Testing
- E2Nomac
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sydney Centre for Reproductive Health Research
Healthy Volunteer Study
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Ethinyl Estradiol/Levonorgestrel (EE/LNG)
Drug-drug interaction study between Ethinyl Estradioll/Levonorgestrel and Bemnifosbuvir/Ruzasvir
- Trial name
- NCT07272889
- Testing
- Ethinyl Estradioll/Levonorgestrel (EE/LNG), Bemnifosbuvir/Ruzasvir (BEM/RZR), Bemnifosbuvir/Ruzasvir (BEM/RZR) + Ethinyl Estradioll/Levonorgestrel (EE/LNG)
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Atea Pharmaceuticals, Inc.
Contraceptive Usage
Assess Performance Attributes and Acceptability of Non-medicated Intravaginal Rings Among Sexually Active Women in Atlanta, GA
A randomized open label crossover trial to assess performance attributes and acceptability of non-medicated intravaginal rings among sexually active women in Atlanta, GA
- Trial name
- NCT07039591
- Testing
- Pro-type IVR
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Population Council