Clinical trials: Contraceptive Devices
Contraception
An Open-label Study to Evaluate Contraceptive Efficacy and Safety of the Transdermal Contraceptive System of Norelgestromine and Ethinyl Estradiol
The purpose of this study is to evaluate the contraceptive efficacy, safety, cycle control, compliance, and subject satisfaction of the transdermal contraceptive system, norelgestromine and ethinyl estradiol (NLGM / EE).
- Trial name
- NCT00307632
- Testing
- Norelgestromine (NLGM)/ethinyl estradiol (EE)
- Where
- 12 sites in Brazil, Mexico
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Janssen-Cilag Farmaceutica Ltda.
Healthy
A Study of New Transdermal Contraceptive Patch at End of Shelf Life and Currently Marketed EVRA at the Beginning of Shelf Life in Healthy Women
The main objectives of this study are to determine the bioequivalence of the hormones (example, norelgestromin [NGMN] and ethinyl estradiol [EE]) from the transdermal contraceptive patch using the newly sourced adhesive component…
- Trial name
- NCT04017195
- Testing
- EVRA patch (NGMN+EE) (Treatment A) (Reference), High molecular weight polyisobutylene (HMW PIB) patch (NGMN+EE) (Treatment B) (Test)
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Pharmacokinetics
Comparison of Serum Contraceptive Hormone Levels Between Normal Weight and Obese Users of the NuvaRing®
There are over 60 million women of reproductive age in the U.S. and a majority of these women qualify as overweight or obese. Evidence suggests that there is an association between increased body weight and decreased…
- Trial name
- NCT00710606
- Testing
- NuvaRing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV, Contraception
The Evidence for Contraceptive Options and HIV Outcomes Trial
The ECHO Study is an open-label randomized clinical trial that will compare three highly effective, reversible methods of contraception (including a non-hormonal method) to evaluate whether there is a link between use of any of…
- Trial name
- ECHO (NCT02550067)
- Testing
- DMPA, LNG, Copper IUD
- Where
- 12 sites in Eswatini, Kenya and 2 more
- Volunteers
- 7,830 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraception
Postpartum Family Planning Service Through Enhanced Family Planning in Immunization Services
The purpose of this study is to determine the effectiveness of an intervention, which is designed to increase contraceptive prevalence among postpartum women attending vaccination services who desire to either space or limit…
- Trial name
- PPFP-IZ (NCT01115361)
- Testing
- Family planning for postpartum women
- Where
- Rwanda
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraception, Liver Metabolism
"E4/DRSP Endocrine Function, Metabolic Control and Hemostasis Study"
The proposed study will provide an assessment of the effect of this combination on endocrine function, metabolic control and hemostasis during 6 treatment cycles. This will be compared to the effects of two reference COCs.
- Conditions
- Contraception, Liver Metabolism, Hemostasis Parameter
- Trial name
- NCT02957630
- Testing
- 15 mg E4/3 mg DRSP, 30 mcg EE/150 mcg LNG, 20 mcg EE/3 mg DRSP
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Estetra
Contraceptive Behavior
Meaningful Use of Technology to Improve Health Care Delivery
While there have been major declines in teenage pregnancy around the country, Baltimore, Maryland has continued to experience increases over the last several years.
- Trial name
- DepoText (NCT01641380)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Contraception
Shoulder Contraceptive Implant Study
This study will be the first to establish pharmacokinetic curves for the etonogestrel contraceptive implant with scapular subdermal insertion.
- Trial name
- NCT04463693
- Testing
- Etonogestrel implant
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Healthy Participants
A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
This study will measure the effects of multiple doses of AZD6234, AZD9550 and a combination of AZD9550 and AZD6234 given as injection(s) on pharmacokinetics (PK) of combined oral contraceptive (CoC) ethinyl estradiol…
- Trial name
- NCT07013643
- Testing
- AZD6234, Ethinyl estradiol/Levonorgestrel (EE/LEVO), Acetaminophen (APAP)
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Contraception, Contraception Behavior
Contraception for Solid Organ Transplant Patients: Utilizing Social Media
The purpose of this study is to use an electronic survey to explore Solid Organ Transplant patients' contraceptive knowledge and counseling.
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Reproductive Health
- Trial name
- NCT03979950
- Testing
- Survey
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Contraception
Study Investigating the Efficacy and Safety of a Contraceptive Patch for 13 Cycles
This study is examining a birth control patch for 13 cycles (1 year).
- Trial name
- NCT00910637
- Testing
- Gestodene/EE Patch (BAY86-5016)
- Where
- 63 sites in United States
- Volunteers
- 1,502 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Immediate Postpartum Insertion of Contraceptive Intrauterine Devices
In this randomized trial, investigators intend to determine the expulsion and discontinuation rate of immediate postpartum intrauterine devices in the patient population of the University of Oklahoma Women's Healthcare…
- Trial name
- NCT03657602
- Testing
- Kyleena Intrauterine System, Mirena Intrauterine System
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Contraception
Contraceptive Choice at the Time of Uterine Evacuation
The goal of this project is to investigate whether a pre-visit telephone intervention could increase awareness of long-acting reversible contraception (LARC) availability at the time of uterine evacuation.
- Trial name
- NCT02836561
- Testing
- Telephone message
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Copper Intrauterine Device Induced Bleeding
Study About Patients Using Copper Intrauterine Device
THE AIM OF THE this study is to assess the hemodynamic changes of uterine artery in patients with CIUD induced bleeding by using transvaginal color Doppler indices (uterine artery resistance index and pulsatility index) to prove…
- Trial name
- IUD (NCT01541241)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Bleeding, Implants
Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users
The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- NCT04205929
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception, Health Behavior
Contraception Training Using the Transtheoretical Model in Students (CT-TTM)
What was the study about? This study tested whether a special training program based on the Transtheoretical Model (TTM) could help university students improve their knowledge, attitudes, and actual behavior related to…
- Trial name
- CT-TTM (NCT07258966)
- Testing
- Contraceptive method training
- Where
- Cyprus
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Emergency Contraception, Healthy, Reproductive Age Women
Application for the Etonogestrel/Ethinyl Estradiol Ring
This study is enrolling healthy women ages 18-39yo who are not pregnant or breastfeeding, and are not using hormonal birth control.
- Trial name
- AFTER (NCT03120728)
- Testing
- Etonogestrel/ethinyl estradiol contraceptive vaginal ring
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Mechanical Complication of Intrauterine Device
Immediate Post-placental Insertion of IUCD During Cesarean Delivery Versus 6 Week Post-Cesarean Insertion
The aim of current study is to compare the rates of IUCD expulsion and complications in immediate post-placental insertion versus delayed IUCD insertion (6-weeks after cesarean delivery)
- Trial name
- NCT03404622
- Testing
- IUCD
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ALshaimaa Aboalhassan Ali
Women at Risk for Pregnancy
Evaluation of Efficacy, Safety and Tolerability of VeraCept IUS
To assess the contraceptive efficacy (prevention of pregnancy) of VeraCept
- Trial name
- NCT03633799
- Testing
- VeraCept
- Where
- 41 sites in United States
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.