Clinical trials: Contraceptive Devices
Premenstrual Dysphoric Disorder
Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD)
The purpose of this study is to compare a low dose oral contraceptive (OC) given continuously (every day for three months) with the same low dose oral contraceptive given in an interrupted regimen (one week of inactive placebo…
- Trial name
- PMDD (NCT00927095)
- Testing
- Continuous OC (EE/DROS), Intermittent OC (EE/DROS)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of North Carolina, Chapel Hill
Contraception, Ovulation
Ovulation Incidence in Oral Contraceptive Users
Since the introduction of the combined hormonal contraceptive pill, dosages of ethinyl estradiol (EE) have steadily decreased from more than 150mcg to 20mcg in an attempt to improve the risk profile associated with the COC.
- Trial name
- NCT03106454
- Testing
- Ethinyl Estradiol, Norethindrone acetate, ferrous fumarate, Norethindrone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Adverse Effect of Oral Contraceptives, Sequela
Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
The main aims of this study are: to investigate and compare the effects of long lasting use (59 weeks) of vaginal and oral contraceptives on androgen secretion, insulin and glucose metabolism, lipid profile, and serum levels of…
- Trial name
- NCT01588873
- Testing
- oc:E-E-desogestrel/vaginal ring:E-E -ethonogestrel
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Menstrual Cycle, Oral Contraceptive
Social Media Usage in Adolescent Girls
The study aims to explore the effects of hormonal fluctuations throughout the menstrual cycle on social media use, brain architecture, neural reward processing and reward behavior, and affective status in adolescent girls.
- Trial name
- NCT06426459
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Menstrual Problem, Quality of Life
Menstrual Wellbeing in Woman Living in Turkey; an Epidemiological Study
Women with endometriosis in our country and around the world face various difficulties during their menstrual periods in reproductive age.
- Trial name
- NCT05442541
- Testing
- not included any interventions(Evaluation of menstrual well-being in women of reproductive age, field survey study)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,829 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Menorrhagia
Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood Loss
Intrauterine contraceptive device is the most commonly reversible method used among women of reproductive age worldwide. Almost one in five married contraceptive users is currently using Intrauterine contraceptive device.
- Trial name
- NCT03139422
- Testing
- Tranexamic Acid 500 MG, Calcium Dobesilate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Contraceptive; Complications, Intrauterine
Surveillance Study of the Contraceptive Intrauterine Device UT380®
The study is a long term Post Market Surveillance Study involving women who will received UT 380® device as a contraceptive method.
- Trial name
- CCDDIUUT (NCT03642171)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Quanta Medical
Bariatric Surgery Candidate, Contraception
Changes in Oral Contraceptive Hormones After Gastric Bypass Surgery
This study will attempt to determine whether having gastric bypass surgery changes the way that the gut absorbs hormones from birth control pills.
- Trial name
- NCT01941134
- Testing
- ethinyl estradiol-levonorgestrel
- Where
- United States
- Sponsor
- Johns Hopkins University
Contraception
Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods
This is a randomized, multi-center, parallel-group Phase I study to evaluate the pharmacodynamics (PD) of Medroxyprogesterone Acetate (MPA) after a single subcutaneous (SC) injection of 150 mg/mL or 300 mg/2 mL Depo-Provera CI in…
- Trial name
- NCT02456584
- Testing
- DMPA 150, DMPA 300, DMPA 104
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- FHI 360
Libido
Efficacy and Safety of Oral Dehydroepiandrosterone as a Concomitant Therapy to Oral Contraceptives in Women Complaining of Reduced Libido
The purpose of the study is to evaluate the effectiveness of the study drug on the libido (sexual desire) of women who are taking oral contraceptives and who have experienced libido reductions as a side-effect of this…
- Trial name
- NCT00566384
- Testing
- Dehydroepiandrosterone, BAY86-5314
- Where
- 11 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Bayer
Contraception
Family Planning Elevated: Initiative Evaluation
Family Planning Elevated (FPE) is a statewide contraceptive initiative with two primary aims: 1) supporting existing and proposed legislative policy that expands family planning services in Utah among low-income individuals…
- Trial name
- NCT03877757
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Utah
Follicle Development, Ovarian Follicle
A Study to Evaluate Ovarian Follicular Activity and Hormone Levels for DR-102 Compared to Two 28-Day Oral Contraceptives
This study is being conducted to evaluate the impact of a 28-day oral contraceptive compared to two 28-day oral contraceptive regimens containing different synthetic progestins on ovarian follicular activity and hormone levels in…
- Conditions
- Follicle Development, Ovarian Follicle, Follicle Count, Follicle Size
- Trial name
- NCT01291004
- Testing
- Desogestrel/ethinyl estradiol and ethinyl estradiol, 28-day drospirenone oral contraceptive, 28-day levonorgestrel oral contraceptive
- Where
- 2 sites in United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
HIV
Optimization of the ex Vivo Challenge: Reproductive Infections and Contraception
The development of surrogates to predict HIV prevention product safety and efficacy is a high priority. An ex vivo challenge model is one such promising surrogate.
- Trial name
- NCT02375425
- Testing
- no intervention
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Effect of Evobrutinib on Pharmacokinetics of a Combined Oral Contraceptive
The purpose of this study was to assess the effect of M2951 on the pharmacokinetics (PK) of a combined oral contraceptive [Ethinyl estradiol/Norethisterone (EE/NET)] in healthy female participants.
- Trial name
- NCT07215806
- Testing
- Evobruitnib, Combined oral contraceptive [ethinyl estradiol/ norethisterone (EE/NET)]
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Contraceptive Affecting the Autonomic Nervous System, Contraceptive Affecting Blood Pressure
Assessment of Autonomic Tone in Normotensive Women Using Combined Hormonal Oral Contraceptive Containing Drospirenone
The use of combined oral contraceptives has been associated with increased risk of adverse cardiovascular events. The exact mechanism by which these drugs exert this influence is uncertain.
- Trial name
- NCT01590849
- Testing
- Contraceptives, Oral, Combined (Yaz®)
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Instituto do Coracao
Ovarian Diseases
Antral Follicle Priming Prior to ICSI (Intracytoplasmic Sperm Injection) in Previously Diagnosed Low Responders
The aim of this study is to compare the effectiveness of testosterone,estradiol and a combined treatment with estrogens/progestagens prior to IVF-ICSI in previously diagnosed low responder patients.
- Trial name
- FOLLPRIM (NCT01310647)
- Testing
- Testosterone, Estradiol, CombEq
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Women Wanting Contraceptive Implant for Pregnancy Prevention
A Trial on the Effect of Sino-implant (II) Use on Condom Use Among Women in Kingston, Jamaica
This unblinded, randomized controlled trial (RCT) among women to determine: 1)if unprotected sex as measured prostate-specific antigen (PSA) will be more among women who receive a contraceptive implant immediately at baseline…
- Trial name
- SIS (NCT01684358)
- Testing
- Sino-implant (II)
- Where
- Jamaica
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2
A Study of the Effects of GSK189075 on PK Profiles of an Oral Contraceptive Pill When Given to Healthy Female Volunteers
The purpose of this research study is to demonstrate a lack of effect of multiple doses of GSK189075 on the PK of an oral contraceptive pill in healthy female subjects.
- Trial name
- NCT00504816
- Testing
- GSK189075, Brevicon
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Menstruation Disturbances, Metrorrhagia
Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users
The goal of this clinical trial is to evaluate the effectiveness of transdermal contraceptive patches in treating irregular vaginal bleeding in women over 18 years old who are using contraceptive implants and experiencing…
- Conditions
- Menstruation Disturbances, Metrorrhagia, Uterine Hemorrhage, Contraception Behavior
- Trial name
- NCT07083635
- Testing
- Transdermal Ethinyl Estradiol/Norelgestromin Patch
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Chulalongkorn University
Contraception Desired, Obesity
Levonorgestrel-releasing Intrauterine Device on Obese Women: Effects on Hemostatic and Arterial Function
Obesity is a disorder associated with metabolic dysfunction and changes in cardiovascular risk markers; the use of oral contraceptives (OCs) may exert a further negative effect on these alterations in patients with PCOS.
- Trial name
- NCT01320917
- Testing
- Levonorgestrel releasing device, Cu-IUD insertion
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo