Clinical trials: Contraceptive Devices
Dysfunctional Uterine Bleeding
Misotac vs Combined Oral Contraceptive Pill in the Treatment of Symptomatic Isthmocele
Isthmocele is a growing concern as a cause of abnormal uterine bleeding, especially post menstrual bleeding which may be present in up to 82% of these cases (Iannone et al 2019).
- Trial name
- NCT04579965
- Testing
- medical treatment of isthmocele
- Volunteers
- 50 people
- Sponsor
- Mansoura University Hospital
Contraception
The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies
Hormonal birth control methods include birth control pills, patches, and vaginal rings; they are normally available only with a doctor's prescription.
- Trial name
- NCT00065871
- Testing
- Contraceptive Screening by Pharmacist, Contraceptive Prescribing by Pharmacist
- Where
- 5 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Contraception, Tuberculosis
Rifampin and the Contraceptive Implant
It is important for women taking rifampin to be aware if they are at greater risk of an unintended pregnancy while on the implant. An unintended pregnancy has many social, emotional, and financial impacts on women and society.
- Trial name
- NCT04463680
- Testing
- Rifampin 600 MG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Study to Evaluate the Effects of Neramexane on the Pharmacokinetics of a Combined Drospirenone/Ethinyl Estradiol Oral Contraceptive in Healthy Female Subjects
Primary: To assess the effects of repeated dose of Neramexane on the steady-state pharmacokinetics of Drospirenone [DRSP] and Ethinyl Estradiol [EE] Secondary: To assess safety and tolerability of concomitant repeated dose…
- Trial name
- NCT00915174
- Testing
- Neramexane
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Contraceptive Usage, Alcohol Use Complicating Childbirth
Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study
Native CHOICES is a randomized controlled trial of an adapted intervention to reduce the risk of alcohol exposed pregnancies in American Indians and Alaska Natives (AI/ANs).
- Conditions
- Contraceptive Usage, Alcohol Use Complicating Childbirth, Alcohol Drinking
- Trial name
- Native-CHOICES (NCT03930342)
- Testing
- Native-CHOICES
- Where
- 2 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Washington State University
Oral Contraceptive
Bleeding Pattern Study
The aim of this study is to evaluate bleeding pattern, cycle control, contraceptive efficacy and safety of this oral contraceptive in two different regimens of intake.
- Trial name
- NCT00302666
- Testing
- Valette (Dienogest/EE30, BAY86-5038)
- Where
- 48 sites in Germany
- Volunteers
- 1,315 people, healthy volunteers welcome
- Sponsor
- Bayer
Male Sterilization
Implantable Device for Male Reproductive Sterilization
The study is to evaluate a device for male reproductive sterilization and determine if this device is successful at blocking the sperm. Ninety subjects from two centers in the United Stated will be followed closely for 24 months.
- Trial name
- NCT00335361
- Testing
- Intra Vas Device (IVD)
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shepherd Medical Company
Contraception
Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles
To demonstrate the contraceptive efficacy of LF111 . To demonstrate the safety and tolerability of LF111 and assessment of pharmacokinetics of LF111.
- Trial name
- NCT02269241
- Testing
- LF111 (drospirenone)
- Where
- 37 sites in United States
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- Laboratories Leon Farma, S.A.
HIV, AIDS
TMC278-TiDP6-C136: Effect of TMC278 on Ethinylestradiol and Norethindrone in Healthy Women.
The purpose of this study is to investigate the pharmacokinetic interaction between the combination of ethinylestradiol and norethindrone and TMC278 25 mg once daily.
- Conditions
- HIV, AIDS, Oral Contraceptive
- Trial name
- NCT00739622
- Testing
- TMC278
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Contraception Behavior
Evaluating What's My Method? in Barbados
The purpose of this study is to measure the impact of the What's My Method game on participants' sense of agency, education, and empowerment around contraceptive decision-making.
- Trial name
- NCT06307002
- Testing
- Playing a contraception education videogame
- Where
- Barbados
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Quinnipiac University
Contraception
Yasmin Post Marketing Surveillance
The objective of this Post Marketing Surveillance (PMS) is to gain information about safety and efficacy in real practice.
- Trial name
- NCT00923572
- Testing
- EE30/DRSP (Yasmin, BAY86-5131)
- Where
- South Korea
- Volunteers
- 777 people
- Sponsor
- Bayer
Family Planning Services
The Importance of Including Reproductive Life Plan Counseling During Contraceptive Counseling
The reproductive life plan is a protocol intended to promote preconception planning, improve reproductive health and increase health knowledge.
- Trial name
- NCT05530928
- Testing
- Reproductive life plan counseling
- Where
- 2 sites in Lebanon
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Dysmenorrhea, Menstruation Disturbances
Continuous Use of the Contraceptive Patch and the Personal Economic Impact.
Dr. Eleanor Drey in the Department of Obstetrics, Gynecology and Reproductive Sciences UCSF is conducting a study to examine the personal and economic impact of continuous use of ORTHO EVRA, the contraceptive patch, on menstrual…
- Conditions
- Dysmenorrhea, Menstruation Disturbances, Menstruation Disorders
- Trial name
- NCT00357981
- Testing
- ORTHO EVRA, the contraceptive patch
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
A Multicentre, Prospective, Open-label, Non-comparative Study
As there are no recent studies conducted in Italy on the profile of this COC, the purpose of this study is to evaluate its efficacy and tolerability in a given subset of women residing in Italy that are in need of contraception.
- Trial name
- NCT06067256
- Testing
- Female Contraceptive
- Where
- Italy
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Italfarmaco
Birth Control, Contraception
RCT Evaluating Standardized Counseling on Early Discontinuation for Irregular Bleeding in Nexplanon Users
Clinician counseling for implant users should involve an explanation of the likelihood of irregular bleeding and the possibility of continued or frequent bleeding throughout three years of use.
- Conditions
- Birth Control, Contraception, Contraceptive Usage, Family Planning
- Trial name
- NCT04558229
- Testing
- Additional Standardized Counseling
- Where
- United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of the St. Louis Region and Southwest Missouri
Infections, Human Immunodeficiency Virus and Hepatitis
Study to Evaluate the Pharmacokinetics of an Oral Contraceptive Containing Levonorgestrel and Ethinyl Estradiol When Co-administered With GSK1265744 in Healthy Adult Female Subjects
This open-label, fixed-sequence crossover study aims to evaluate the effect of GSK1265744 (744) oral administration on the pharmacokinetics (PK) and pharmacodynamics (PD) of a commonly used oral contraceptive (OC) product…
- Trial name
- NCT02159131
- Testing
- Ethinyl Estadiol, Levonorgestrel, GSK1265744
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Contraception
Evaluation of a Novel Technique for Intrauterine Contraceptive Devices Insertion
The intrauterine devices are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years.
- Trial name
- NCT02842177
- Testing
- Classic group, Uterine sounding sparing group, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Assiut University
Social Stigma, Pregnancy
A Pre and Post Test Intervention Design to Prevent Abortion and Contraceptive-use Stigma Among School Youths in Kenya
In many low-income countries, unsafe abortion is recognized as a leading cause of maternal morbidity and mortality. Social stigma surrounding abortion and contraceptive use plays a critical role in the social, medical, and legal…
- Conditions
- Social Stigma, Pregnancy, Contraception
- Trial name
- SAC (NCT03065842)
- Testing
- Abortion- and contraceptive-use stigma reduction program, Usual Standards
- Where
- Kenya
- Volunteers
- 1,207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Contraception
Cycle Control Assessment of a Combined Oral Contraceptive Containing Estetrol and a Progestin P1 or P2
This is an open-label, multi-centre, comparative study in young, healthy, female volunteers of reproductive age. Primary objective: To investigate the effect of 2 dosages of estetrol combined with P1 or P2, on vaginal bleeding…
- Trial name
- FIESTA (NCT01221831)
- Where
- 10 sites in Finland
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Estetra
Contraceptive Usage
Increase First-time Mothers' Use of Postpartum Family Planning in Bangladesh: The Connect Project
While a growing body of programs have shown promise to increase uptake of contraception among FTMs, difficulties remain in scaling beyond small pilot areas and institutionalizing within existing systems.
- Trial name
- Connect BD (NCT06666036)
- Testing
- Connect
- Where
- Bangladesh
- Volunteers
- 2,308 people, healthy volunteers welcome
- Sponsor
- George Washington University