Clinical trials: Contraction
Muscle Damage
Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration
The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration. The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
- Trial name
- NCT00832663
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Vibration
Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performance
The goal of this interventional cross-sectional study is to evaluate motor responses to non-invasive vibratory stimulation applied to the hamstring muscle tendons in healthy individuals.
- Trial name
- VIBMOT (NCT07424066)
- Testing
- Vibratory stimulation
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Sedentary Lifestyle
Effectiveness of Adding Voluntary Pelvic Floor Muscle Contraction to a Pilates Exercises Program
Adding voluntary pelvic floor muscle contraction to a Pilates exercises program can improve the pelvic floor muscle strength on sedentary nulliparous women.
- Trial name
- NCT02748473
- Testing
- Pilates Exercises program, Pelvic floor muscle strength, 3D perineal ultrasound
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Obstructive Sleep Apnea, Breathing, Sleep-Disordered
Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study
Cheeks appearance is a screening tool developed based on cheeks observation to identify volume, flaccidity or both to predict people with probable obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Breathing, Sleep-Disordered, Muscle Weakness, Muscle Disorder
- Trial name
- CASA (NCT04980586)
- Testing
- CASA score protocol to Non-obstructive sleep apnea Group, CASA score protocol to Mild obstructive sleep apnea Group, CASA score protocol to Moderate obstructive sleep apnea Group
- Where
- Brazil
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Premature Ventricular Contractions
Concealed Myocardial Abnormalities by Cardiac Magnetic Resonance Imaging in Idiopathic VT
Idiopathic Ventricular arrhythmia (VAs) refers to VAs that occur in the absence of clinically apparent structural heart disease.
- Trial name
- NCT06146556
- Testing
- catheter based ablation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pelvic Floor Muscle Weakness
What is the Best Verbal Instruction for Contraction the Pelvic Floor Muscles?
The aim of this study is to T to compare the effectiveness of producing a pelvic floor muscle contraction by different verbal instruction.
- Trial name
- NCT03400540
- Testing
- verbal instruction
- Where
- Israel
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Healthy
Influence of Fast and Slow Imagined Muscle Contractions on Muscle Function or Central Nervous System Properties
The goal of this randomized clinical trial is to learn if imagining fast or slow muscle contractions causes different responses for nervous system excitability and muscle function in young, healthy males and females in.
- Trial name
- NCT06627491
- Testing
- Imagined muscle contractions
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Healthy Participants
Pain Inhibition With Neuromuscular Electrical Stimulation
The purpose of this study is to demonstrate the pain relieving effect of neuromuscular electrical stimulation that is applied for the purpose of increasing muscle force output.
- Trial name
- NCT05280522
- Testing
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New England
Preterm Labor
Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor
The purpose of this study is to evaluate the effect of oral progesterone supplementation in preterm labor on the prevention of recurrent uterine contraction and prolonging pregnancy period, and its side effect.
- Trial name
- NCT02262481
- Testing
- dydrogesterone
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Labor
Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE
Labor analgesia is an important component of the care of laboring patients. A known side effect of combined spinal and epidural anesthesia (a type of labor analgesia) is an increased incidence of category II fetal heart rate…
- Trial name
- NCT05873218
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Hemorrhage
Impact of Uterotonic Agents on Isolated Human Myometrium
The purpose of this study is to compare the ability of a sample of uterine muscle tissue to contract in the presence of various drugs.
- Trial name
- NCT00989027
- Testing
- Oxytocin, Ergonovine, Carboprost
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pelvic Floor Muscle Weakness
Comparison of Teaching Methods of Pelvic Floor Muscle Contraction in Women
The aim of our study; To evaluate the effectiveness of different teaching methods on correct pelvic floor muscle contraction in women who have not received pelvic floor muscle training (PFMT) before.
- Trial name
- NCT06306703
- Testing
- group1, group2, group 3
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Duygu Sultan Oge
Muscle Activity, Electromyography
Muscle Activity of the Gastrocnemius and Soleus Muscles by Surface Electromyography.
This cross-sectional, comparative study aims to evaluate and compare the surface electromyographic (sEMG) activity of the gastrocnemius (medial and lateral) and soleus muscles during static and dynamic contraction tasks.
- Conditions
- Muscle Activity, Electromyography, Lower Limb
- Trial name
- NCT06953401
- Testing
- Muscle contraction protocol for electromyographic assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Postpartum Hemorrhage
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
This study will investigate the effects of drugs called "uterotonics" that help with the contraction of the uterus after a baby is born. This uterine contraction is very important to stop the bleeding after delivery.
- Trial name
- NCT06285409
- Testing
- Carbetocin, Oxytocin, Ergonovine
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Physical Activity
Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy
The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults.
- Trial name
- MoTrMito (NCT04799171)
- Testing
- Isometric Contraction Exercise - Young Adults (Age group 18-39), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59), Isometric Contraction Exercise - Old Adults (Age group >60)
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Aging, Muscle Strength
Mental Effort and Muscle Strength
The purpose of this study is to determine the effect of mental effort on improving muscle strength.
- Trial name
- NCT00059436
- Testing
- Mental effort in muscle strengthening
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin Antagonist on Reduction of Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban compared to placebo on uterine contractions on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- EFFORT (NCT01043120)
- Testing
- Barusiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Abdominal Muscles
Abdominal Electromyographic Control in Vojta Therapy
A randomized clinical trial on a cohort of healthy subjects of legal age, both sexes, recruited from the university community and who will be randomly distributed into two groups (experimental and control).
- Trial name
- NCT04818879
- Testing
- Vojta, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Soccer, Performance
Isometric vs. Dynamic Squat Pre-Loading: Acute PAPE Responses
This randomized crossover study compared the acute post-activation performance responses to isometric and dynamic squat-based preconditioning protocols performed with and without electromyostimulation (EMS).
- Conditions
- Soccer, Performance, Contraction
- Trial name
- IPP vs DPP (NCT07696026)
- Testing
- dynamic conraction, isometric contraction, dynamic and EMS contraction
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Uterine Atony, Uterine Tone Disorders
Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Insufficient uterine tone resulting in atony can potentiate hemorrhage and adverse outcomes for the parturient. Oxytocin is the first pharmacologic agent used, followed by methylergonovine, carboprost, and misoprostol.
- Conditions
- Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
- Trial name
- NCT03303235
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University