Clinical trials: Contractions
Postpartum Hemorrhage
Investigating the Effect of Extracellular Calcium on Oxytocin-induced Human Myometrial Contractility In-vitro
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide and is caused most commonly by poor uterine muscle tone after delivery.
- Trial name
- NCT02274454
- Testing
- Oxytocin, Calcium
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy Related, Labor; Poor
Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy
Today it remains a challenge to successfully both halt and induce labor progression. Induction of labor is a common obstetric intervention that 1 in 4 women will experience.
- Conditions
- Pregnancy Related, Labor; Poor, Uterine Contractions Weak
- Trial name
- NCT04521972
- Testing
- Room light/light bulb
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Physical Activity
Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy
The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults.
- Trial name
- MoTrMito (NCT04799171)
- Testing
- Isometric Contraction Exercise - Young Adults (Age group 18-39), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59), Isometric Contraction Exercise - Old Adults (Age group >60)
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Labor Pain, Contraction
Fetal Life: Smart-Device Based Uterine Activity Monitoring
This study will compare the performance of a contraction monitor (tocometer) device developed by Fetal Life with standard tocometer devices.
- Trial name
- NCT03940365
- Testing
- Fetal Life tocometer device
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Fetal Life LLC
Premature Ventricular Contractions
Use of MIBG Scan Images in PVC Ablations
The purpose of this study is to assess if Single Photon Emission Computed Tomography (SPECT) demonstrating cardiac innervation can be integrated into current electrophysiology voltage mapping system and provide improved guidance…
- Trial name
- PVC-MIBG (NCT02279030)
- Testing
- MIBG nuclear scan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Multifidus
Estimation of Muscle Area and Thickness of Deep Cervical Muscle Contraction During Cervical and Limb Movements
The purpose of this study is to investigate the validity and reliability of measurement for cervical multifidus using ultrasonography, and to investigate cervical multifidus muscle function by the change pattern of multifidus…
- Trial name
- NCT00155948
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Whole Body Vibration
Frequency and Voluntary Contraction-Dependent Activation of Tonic Vibration Reflex and Bone Myoregulation Reflex
When vibration is applied, sensors inside the muscle send signals to the nervous system, leading to automatic muscle activation.
- Trial name
- WBV-BMR (NCT07386145)
- Testing
- whole-body vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Premature Atrial Contractions, Premature Ventricular Contractions
The MARY-JANE Cannabis and Heart Rhythm Trial
Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited.
- Trial name
- NCT06021613
- Testing
- Randomized instructions
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin Antagonist on Reduction of Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban compared to placebo on uterine contractions on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- EFFORT (NCT01043120)
- Testing
- Barusiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Healthy Participants
Pain Inhibition With Neuromuscular Electrical Stimulation
The purpose of this study is to demonstrate the pain relieving effect of neuromuscular electrical stimulation that is applied for the purpose of increasing muscle force output.
- Trial name
- NCT05280522
- Testing
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New England
Glenohumeral Internal Rotation Deficits
Effect of a Novel Stretching Technique on Shoulder Range of Motion and Voluntary Contraction in Overhead Athletes With Glenohumeral Internal Rotation Deficits "GIRD"
To examine and compare the effect of a novel stretching technique and traditional stretching on glenohumeral range of motion, strength, maximum voluntary contraction, pain, and subject satisfaction in overhead athletes with…
- Trial name
- GIRD (NCT03044236)
- Testing
- Stretching
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Neurocognitive Dysfunction
Transseptal vs Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli
This study is a prospective, multicenter, randomized (1:1) controlled comparative effectiveness trial of a transseptal approach to left ventricular ablation compared to a retrograde aortic approach to prevent cerebral emboli and…
- Trial name
- TRAVERSE (NCT03946072)
- Testing
- Transseptal Aortic Approach Catheter Ablation Procedure, Retrograde Aortic Approach Catheter Ablation Procedure
- Where
- 21 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Uterine Contractions; Prolonged, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
A Home Telemonitoring System for Wearable Fetal-ECG and EHG Acquisition During Pregnancy
The goal of this observational is to compare in describing fetal health conditions. The main questions it aims to answer are: fetal electrocardiogram (fetal heart rate and fetal rhythm) electrohysterography (uterine…
- Conditions
- Uterine Contractions; Prolonged, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus, Pregnancy Related, Home Range
- Trial name
- AHTSWFEADP (NCT06031142)
- Testing
- use wearable devices to monitoring fetal health conditions.
- Where
- China
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Fudan University
Subacromial Impingement Syndrome, Central Nervous System Sensitization
Muscle Function, Central Nervous System Sensitization, and Pain Profiling in Patients With Subacromial Pain (SAP-CNSS).
In this case-control study, the investigators compare shoulder muscle function, pain, and central nervous system sensitization in patients with Subacromial Pain (SAP) to that in healthy controls.
- Trial name
- NCT03326466
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Abdominal Muscles
Expert vs. Non-expert Abdominal Electromyographic Control in Vojta Therapy
Randomized clinical trial on a cohort of healthy subjects of legal age, of both sexes, recruited from the university community and who will be randomly distributed into two groups (expert therapist vs. non-expert therapist).
- Trial name
- NCT06159426
- Testing
- Vojta Therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Sarcopenia, Stroke
Studying the Impairment of Stroke and Sarcopenia Patients Using Maximum Voluntary Contractions of the Leg Joints.
The goal of this study is to obtain the maximum voluntary torques of the lower-limb joints and to monitor oxygen level in the main lower-limb muscles. This will be done for three joints: i.e.
- Trial name
- NCT07465328
- Testing
- MVC measurements of participants
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Athletic Performance, Volleyball
Acute Effects of Bilateral Versus Unilateral Isometric Conditioning Activity on Jump Performance in Volleyball Players
This randomized crossover trial investigates the acute effects of bilateral and unilateral isometric conditioning activity on bilateral and unilateral jump performance in highly trained male volleyball players.
- Conditions
- Athletic Performance, Volleyball, Isometric Strength Training, Post Activation Potentiation
- Trial name
- BI-UNI ICA (NCT07709104)
- Testing
- Bilateral Isometric Conditioning Activity, Unilateral Isometric Conditioning Activity, Low-Intensity Treadmill Walking
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy Control Subjects
Optimisation of Eccentric Exercises
Regular physical activity is an important public health lever and is recognised as an alternative in the management of certain long-term conditions.
- Trial name
- OPTIMEX (NCT06193824)
- Testing
- Experimental: downhill treadmill walking at -10% and -20% gradient
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Ventricular Premature Complexes, Atrial Premature Complexes
Oral Magnesium Supplementation in Athletes With Premature Ventricular Contractions or Premature Atrial Contractions.
Magnesium is a mineral which is essential to many of the processes which happen in the body. This includes normal function of muscles; including the heart.
- Trial name
- NCT04186728
- Testing
- Magnesium glycinate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postpartum Hemorrhage
Investigating the Effect of Pulsatile Administration of Oxytocin on the Desensitization of Human Myometrium In-vitro
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide and is caused most commonly by poor uterine muscle (myometrium) tone after delivery.
- Trial name
- NCT02338089
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital