Clinical trials: Contrast Agent
COVID 19
B Cell Responses in COVID-19
In this study, we will develop techniques to optimize the in vitro production of human monoclonal antibodies.
- Trial name
- NCT06891170
- Where
- Italy
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Short-Term Renal-Hematologic Safety, Contrast-Enhanced MRI and FDG-PET/CT
Comparative Evaluation of Contrast-Enhanced MRI and FDG-PET/CT in Spinal Pathology: Image Quality and Short-Term Renal-Hematologic Safety
This prospective comparative observational study evaluates image quality characteristics and short-term physiological effects associated with contrast-enhanced magnetic resonance imaging (MRI) and fluorodeoxyglucose positron…
- Conditions
- Short-Term Renal-Hematologic Safety, Contrast-Enhanced MRI and FDG-PET/CT, Spinal Pathology
- Trial name
- NCT07640386
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety, Stress
Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds
The aim of the current study is to analyze the effect of listening to Quran or music or natural sounds on anxiety and stress level among patients undergoing MRI.
- Conditions
- Anxiety, Stress, MRI Contrast Media Adverse Reaction
- Trial name
- NCT06348862
- Testing
- Listening to either Quran, Music, and or Natural sound
- Where
- Palestinian Territories
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Cystic Fibrosis
Exocrine Pancreatic Function Testing in Cystic Fibrosis
Purpose The purpose of this study is to develop and validate multimodal testing of exocrine pancreatic function (EPF). The investigators will be testing exocrine pancreatic function in patients with cystic fibrosis (CF).
- Trial name
- NCT01446861
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Breast Cancer
Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT
The goal of this observational study is to evaluate the feasibility and effectiveness of using non-contrast chest computed tomography scans for opportunistic breast cancer screening, and to further compare its diagnostic…
- Trial name
- OPBCS-CT (NCT07557654)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Cardiac Disease
A Dose Ascending Study to Evaluate the Safety of NH002 as a Contrast Agent in Cardiac Echocardiography
NH002 (Perflutren Lipid Microspheres) Injectable Suspension is an ultrasound contrast agent for use in patients with suboptimal echocardiograms to opacify the left ventricular (LV) chamber and to improve the delineation of the LV…
- Trial name
- NCT04185246
- Testing
- NH002 (Perflutren Lipid Microspheres) Injectable Suspension, Echocardiogram
- Where
- 2 sites in Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Trust Bio-sonics, Inc.
Resistance Training
Contrast Training, Post-activation Countermovement Jump Performance in High Strength Male
The study investigated the effects of three contrast training sessions in a week on post-activation countermovement jump performance in high strength male.
- Trial name
- NCT05987046
- Testing
- Contrast training
- Where
- Taiwan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Myopia, Moderate
To Compare the Clinical Outcomes of FemtoLASIK and ICL Implantation in Treating Moderate Myopia Focusing on Refractive Stability, Contrast Sensitivity and High Order Aberrations.
Compare the clinical outcomes of FemtoLASIK and ICL implantation in treating moderate myopia.
- Trial name
- NCT07291986
- Testing
- FemtoLASIK, ICL implantation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Walid Osama Abdel Rahman Nour El Din
Peripheral Artery Disease
Optical Imaging Measurement of Intravascular Solution Efficacy Trial
Iodinated contrast is the current gold standard for infrainguinal angiography imaging in patients without renal insufficiency and has also been used with intravascular Optical Coherence Tomography (iOCT) to improve image quality…
- Trial name
- OPTIMISE (NCT01743872)
- Testing
- Contrast Injection, Dextran Injection, CO2 Injection
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Thrombosis
Venous Vascularization and Inflammation on Contrast-enhanced Ultrasound (CEUS) in Patients With Thrombosis
Background: Contrast-enhanced ultrasound (CEUS) visualization of the adventitial vasa vasorum. Late phase CEUS detect inflammation by visualizing microbubbles phagocytosed by monocytes.
- Trial name
- NCT01367769
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Clinical CT Abdomen/Pelvic With Oral Contrast and Sedation
CT Residual Gastric Fluid Volume
Hypothesis: The investigators hypothesize that more than 50% of the patients receiving enteric contrast material (ECM) < 2 hours of anesthesia/sedation would have residual gastric fluid volume (GFV) > 0.4 ml/kg.
- Trial name
- NCT02239068
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Dental Caries
Use of Radiographic Contrast to Detect Dental Caries
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT01523509
- Testing
- Radiographic contrast agent. Sodium Iodide.
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Creighton University
Pulmonary Disease
Chest CT Using Low-concentration Iodine Contrast Media
This study aims to evaluate the quality of images when low-concentration iodine contrast agents is used in chest CT with low tube voltage and if they can be used in routine imaging.
- Trial name
- NCT05967117
- Testing
- Iohexol (320mgI/mL) with 120kVp, Iohexol (320mgI/mL) with 100kVp, Iohexol (270mgI/mL) with 100kVp
- Where
- 6 sites in South Korea
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Jung Im Jung
Gingival Recession
Post-operative Blood Flow Measurements of the Oral Mucosa
Our overall goal is to characterize the role of the microcirculation in healing oral mucosa after routinely applied surgery intervention in order to facilitate treatment.
- Trial name
- LASCAM (NCT02540590)
- Testing
- laser speckle contrast imaging of the oral mucosa, wound fluid measurement
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chagas Cardiomyopathy
Microvascular Endothelial Function in a Cohort of Patients With the Cardiac Form of Chronic Chagas Disease.
The present study aims to evaluate the microvascular endothelial function of a single centre cohort of patients with the cardiac form of Chagas disease, and to search for associations with clinical and laboratory variables.
- Trial name
- NCT03524768
- Testing
- skin laser speckle contrast imaging and video-capillaroscopy
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Chronic Kidney Failure
Improved Estimation of GFR by Cystatin C in Preventing Contrast Induced Nephropathy by NAC or Zn
Background Prevention of contrast media (CM) induced nephropathy (CIN) by pharmacological prophylaxis (e.g. N-acetylcysteine; NAC) is controversially discussed.
- Trial name
- NCT00399256
- Testing
- Acetylcysteine, Zinc
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Alzheimer's Disease, Vascular Dementia
Blood-brain Barrier Leakage in Dementia. A Dynamic Contrast-enhanced MRI Study
Alzheimer's disease (AD) and vascular dementia (VaD) are the most common forms of dementia. Yet, the cause of these diseases is still unknown. A potentially important initiating factor is a disrupted blood-brain barrier.
- Trial name
- NCT02018913
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Fibromyalgia
Dynamic Contrast Enhanced (DCE)-MRI in Fibromyalgia
The primary objective of the current pilot study is to analyze MRI contrast-enhancement patterns in the hands of patients with fibromyalgia as compared to the findings in healthy controls.
- Trial name
- NCT01506817
- Testing
- Dynamic contrast-enhanced MRI of the hands
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital