Clinical trials: Contrast-enhanced US
Nephrotoxicity of CT Contrast Agents, CT Scans in Those With Renal Compromise
Can Ultrasound Replace Computed Tomography (CT) Scan in Those Unable to Have Computed Tomography (CT) Contrast Agents
Computed tomography (CT) scan, performed with contrast enhancement, is one of the most commonly requested examinations in diagnostic imaging.
- Conditions
- Nephrotoxicity of CT Contrast Agents, CT Scans in Those With Renal Compromise, Sensitivity to CT Contrast Agents, US With CEUS as Replacement for Unenhanced CT Scan
- Trial name
- CEUS_CT (NCT01151566)
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Foothills Medical Centre
Non Mass Breast Lesions
Diagnostic Accuracy of Multiparametric Dynamic Contrast Enhanced Magnetic Resonance Imaging in Improving Detection of Ultrasound Non-mass Breast Lesions According to ACR BI-RADS v2025
this study aims To evaluate the diagnostic performance of Ultrasound (US) in correlation with Dynamic Magnetic Resonance Imaging (MRI) for the assessment, characterization, and evaluation of non-mass breast lesions.
- Trial name
- NCT07679308
- Testing
- multiparametric DCE- MRI and US for all patients
- Volunteers
- 60 people
- Sponsor
- Sohag University
Renal Transplantation
CE-US in Renal Transplantation
Acute allograft dysfunction is often observed in the first weeks after kidney transplantation. Renal biopsy is universally considered the gold standard procedure for differential diagnosis of acute allograft dysfunction secondary…
- Trial name
- NCT01815320
- Testing
- Contrast-enhanced ultrasound (CE-US), SonoVue
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Magnetic Resonance Imaging, Hepatocellular Carcinoma
Improving Hepatocellular Carcinoma Screening
This is a monocentric, single blind, interventional, single arm study. It is designed to compare the rates of detection of hepatocellular carcinoma (HCC) by ultrasound (US) used in clinical routine vs.
- Conditions
- Magnetic Resonance Imaging, Hepatocellular Carcinoma, Screening, Contrast-enhanced US
- Trial name
- AMRIK (NCT05828446)
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 330 people
- Sponsor
- Naik Vietti Violi
Malaria, Pyelonephritis
Contrast-Enhanced US of Spleen, Liver and Kidney
To evaluate the changes in the microcirculation of the liver, kidney and spleen during acute infection in patients with malaria (cohorts 1 and 3) and other infectious diseases such as acute pyelonephritis at day 0 (within 8 hours…
- Conditions
- Malaria, Pyelonephritis, Bacterial Infections
- Trial name
- NCT00190281
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Cancer
Open-label Pilot Evaluating Renal Lesions w/ Contrast-enhaced US in Patients w/ Renal Cancer
This prospective pilot study is designed to evaluate the accuracy of contrast-enhanced ultrasound when used to evaluate renal lesions in two different populations; patients with known renal tumors (Cohort 1) and patients with a…
- Trial name
- NCT01751529
- Testing
- Contrast-enhanced Ultrasound, Perflutren lipid
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Crohn Disease, Food Allergy
Contrast-enhanced Ultrasound in Patients With Crohn´s Disease and Food Allergy
The purpose of this study is to investigate differences of the bowel wall thickness visible in conventional ultrasound and bowel perfusion using quantitative Contrast-Enhanced Ultrasound in patients with Crohn´s disease in…
- Trial name
- NCT05768971
- Testing
- Mild diet, Provocative diet
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Hepatocellular Carcinoma (HCC)
Contrast (Sonazoid)-Enhanced US as a Screening Tool for Hepatocellular Carcinoma in Cirrhosis: An Exploratory Cross-sectional Study
B-mode ultrasonography (B-US), a standard method of surveillance of hepatocellular carcinoma (HCC), has a fair sensitivity of 63% in detecting early stage HCC.
- Trial name
- NCT02188901
- Testing
- Sonazoid-enhanced ultrasonography
- Where
- South Korea
- Volunteers
- 523 people
- Sponsor
- Yonsei University
Hepatic Malignant Tumors, Hepatic Perfusion Disorders
Correlation Between CEUS Identification of Nodular HPD on CE-MRI and Hepatic Malignant Lesions
Hepatic malignant tumors are a category of diseases with high incidence and mortality rates worldwide, including various types such as primary hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and liver…
- Trial name
- NCT06816212
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Carcinoma
Assessment of Tumor Vascular Effects of Axitinib With Dynamic Ultrasonography in Patients With Metastatic Colorectal Cancer
The purpose of this study is to evaluate and quantify the dynamic modifications of tumor blood perfusion on axitinib therapy in patients with refractory mCRC for each dose of Axitinib.
- Trial name
- AXUS (NCT01486251)
- Testing
- axitinib
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Pancreatic Disease
Contrast-Enhanced Ultrasound vs Conventional US-guided Percutaneous Needle Biopsy for Pancreatic Diseases: Prospective Multicenter Randomized Controlled Trial
According to previous studies, contrast-enhanced ultrasound (CEUS) -guided Core Biopsy(GB) could improve the diagnosis of biopsy in liver and other superficial mass compared to conventional US-GB.
- Trial name
- NCT05743972
- Testing
- Contrast-enhanced ultrasound-guided core biopsy, Conventional ultrasound-guided core biopsy
- Where
- China
- Volunteers
- 196 people
- Sponsor
- xiao-yan xie
Carotid Artery Stenosis, Atherosclerosis
Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation
The first goal of this study is to investigate whether CE-US is able to accurately identify and quantify neovascularisation in carotid artery plaques.
- Trial name
- NCT00677963
- Testing
- sulphur hexafluoride, gadopentate dimeglumine
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University Medical Center
Ovarian Cancer, Adnexal Lesion
Contrast-enhanced Ultrasound Evaluation of Indeterminate Ovarian Lesions: Prospective Multicenter Study
The goal of this clinical trial is to learn how well contrast-enhanced ultrasound (CEUS) can diagnose ovarian cancer in patients with indeterminate or suspicious ovarian/adnexal lesions identified on routine ultrasound or MRI.
- Trial name
- NCT07849543
- Testing
- Contrast-Enhanced Ultrasound (CEUS)
- Volunteers
- 190 people
- Sponsor
- Thomas Jefferson University
Proliferative Breast Disease
Comparison of Three Methods for Early Detection of Breast Cancer
Subjects with suspicious breast lesion (BIRADS category 4/5) who are scheduled to undergo biopsy will be recruited to undergo imaging evaluation with Contrast Enhanced Dual Energy Mammography (CEDM), Contrast Enhanced Breast MR…
- Trial name
- NCT03954015
- Testing
- Contrast Enhanced imaging, Lumason
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Colorectal Cancer
Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer
Various antiangiogenic agents have a modest effect in prolonging overall survival in solid tumours. In colorectal cancer it is clear that there are some patients in whom bevacizumab significantly prolongs survival, but it is not…
- Trial name
- AUSCOR (NCT03264274)
- Testing
- Aflibercept, Dynamic Contrast Enhanced Ultrasound
- Sponsor
- Barts & The London NHS Trust