Clinical trials: Contusions
Tennis Leg, Muscle Contusion
Residual Eccentric Strength Deficits and Deep Scar Tissue Thickness in Patients With Tennis Leg
This study investigates the relationship between the thickness of deep scar tissue and residual weakness in the calf muscles of patients who have recovered from a condition known as "tennis leg." Tennis leg is a common calf…
- Trial name
- NCT07513779
- Testing
- B-mode Diagnostic Ultrasound - Scar Tissue Assessment, Isokinetic Dynamometry - Eccentric Plantar Flexor Strength Assessment
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Al Hayah University In Cairo
CVD - Cardiovascular Disease, Bruise
The Effect of Standardizing Procedures for SC Injections of LMWH on Patients With CVD
Improper subcutaneous administration of LMWH may cause complications at the injection site. Standardized protocol for subcutaneous LMWH injections in patient with cardiovascular diseases is warranted to ensure consistent best…
- Conditions
- CVD - Cardiovascular Disease, Bruise, Pain
- Trial name
- LMWH (NCT06776159)
- Testing
- Active Control, Standardized injection protocol
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The Hong Kong Polytechnic University
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Liposuction, Bruising
Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction
The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction.
- Conditions
- Liposuction, Bruising, Inflammation, Pain, Postoperative
- Trial name
- CO2L001 (NCT06791577)
- Testing
- Carboxytherapy
- Where
- 3 sites in Brazil, Colombia and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Fasciitis, Plantar, Aponeurosis Contusion
Assessment of Pain in Plantar Fasciitis Managed by Histotripsy
Plantar fasciitis or plantar fasciitis is the most commonly reported cause of pain under the heel. Its prevalence varies from 3.6 to 7% in the general population.
- Trial name
- HISTO-APS (NCT06697834)
- Testing
- Histotripsy ultrasound session, VAS questionnaire, AOFAS questionnaire
- Where
- France
- Volunteers
- 31 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Traumatic Brain Injury
Trauma Molecular Processes
The TRAUMAP study will function as a brain tissue repository for biopsy specimens from patients with traumatic brain injury undergoing brain surgery for contusion removal.
- Trial name
- TRAUMAP (NCT07683169)
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Spinal Cord Injury at T1-T12 Level, Traumatic Thoracic Spinal Cord Contusion
Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI)
The purpose of this feasibility study is to compare the impact of Spinal cord stimulation [SCS] for Spinal Cord Injury (SCI) pain and rehabilitation.
- Conditions
- Spinal Cord Injury at T1-T12 Level, Traumatic Thoracic Spinal Cord Contusion, Thoracic Spinal Cord Trauma, Traumatic Thoracic Spinal Cord Laceration
- Trial name
- NCT04894734
- Testing
- EES on, EES off
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nandan Lad, M.D., Ph.D.
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Traumatic Brain Injury, Cerebral Edema
Trial of Dexamethasone for Traumatic Brain Injured Patients With Brain Contusions and Pericontusional Edema
The DEXCON-TBI trial is a multicenter, pragmatic, randomized, triple-blind, placebo controlled trial to quantify the effects of the administration of dexamethasone on the prognosis of TBI patients with brain contusions and…
- Conditions
- Traumatic Brain Injury, Cerebral Edema, Head Injury Trauma
- Trial name
- DEXCON-TBI (NCT04303065)
- Testing
- Dexamethasone Oral
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Jon Pérez Bárcena
Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines
A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A
Botulinum toxin type A (commonly referred to as 'Botox') injections are a treatment that dermatologists regularly use to smoothen wrinkles such as 'Crow's feet', to rejuvenate the skin surrounding the eye (the 'periorbital…
- Conditions
- Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines, Lateral Canthal Lines, LCL
- Trial name
- NCT07388927
- Testing
- Hirudoid (heparinoids) ointment, 3mg/g
- Volunteers
- 48 people
- Sponsor
- DKSH Management (Thailand) Limited
Edema, Bruising
Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of medrol dosepaks (oral corticosteroids) on postoperative outcomes among patients undergoing rhinoplasty by Facial Plastic Surgeons at Vanderbilt.
- Conditions
- Edema, Bruising, Nasal Obstruction, Postoperative Pain
- Trial name
- NCT06483204
- Testing
- Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Contusions
Phase III Trial to Assess the Safety and Efficacy of TK-254RX in Patients With Contusions
This study is an open-label, multi-centric clinical trial to evaluate the safety and efficacy of TK-254RX in patients with contusions. The primary objective of this study is to assess the safety of TK-254RX.
- Trial name
- NCT06871046
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 221 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Lung Trauma, Lung Contusion
Effects of Non-invasive Ventilation Therapies on the Lung in Hypoxemic Chest Trauma Patients
Chest trauma is common in traumatology. Its management is based on ventilatory therapies, among which non-invasive ventilation (NIV) is commonly used.
- Trial name
- VentiChest (NCT06735872)
- Testing
- Non invasive ventilation (NIV), High flow oxygen therapy (HFO)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Liposuction, Bruising
EFFECTS OF TRANEXAMIC ACID IN TUMESCENT SOLUTION FOR LIPOSUCTION PROCEDURES
The goal of this trial is to evaluate the effect of adding Tranexamic Acid (TXA) to the tumescent solution used in arm liposuction on postoperative outcomes.
- Conditions
- Liposuction, Bruising, Inflammation, Skin Condition
- Trial name
- ARMTXA (NCT06648265)
- Testing
- Tranexamic Acid (Topical), Tumescent solution with dilute lidocaine and epinephrine
- Where
- Colombia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
TSA, Bruise
Natural History of Pain After Shoulder Arthroplasty Conducted With Multimodal Analgesia
This study aims to identify the timeline of pain following total shoulder replacement with the goal of developing data for a subsequent randomized trial.
- Conditions
- TSA, Bruise, Pain, Postoperative
- Trial name
- TSA (NCT03021096)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Stroke, Bruises
Prevention and Treatment for Bruises in Patients With Ischemic Stroke
Background Over the past few decades, significant advances have been made in the diagnosis and treatment of strokes. Most studies focus on functional recovery in stroke patients.
- Conditions
- Stroke, Bruises, Skin Lesions
- Trial name
- NCT06823999
- Testing
- Ascorbic acid (Vitamin C)
- Volunteers
- 400 people
- Sponsor
- Chiayi Christian Hospital
Lung Contusion
AI in the Identification of Lung Contusions Through Chest Radiological Examination in Blunt Thoracic Trauma
The observational study focuses on comparing the interpretation of chest radiological examinations performed using a computer-based system with the standard interpretation conducted by a radiologist.
- Trial name
- NCT06777056
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Flail Chest, Rib Fractures
Mortality Causes in Rib Surgery Patients
This study retrospectively investigates the causes of mortality and morbidity in patients undergoing rib fracture surgery due to blunt trauma.
- Conditions
- Flail Chest, Rib Fractures, Thoracic Injuries, Pulmonary Contusion
- Trial name
- NCT06755723
- Testing
- Rib fractures manangement
- Volunteers
- 112 people
- Sponsor
- Caner İşevi, MD
Brain Contusion
A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion
The primary objective is to determine if BIIB093 reduces brain contusion expansion by Hour 96 when compared to placebo. The secondary objectives are to evaluate the effects of BIIB093 on acute neurologic status, functional…
- Trial name
- ASTRAL (NCT03954041)
- Testing
- BIIB093
- Where
- 63 sites in United States, France and 5 more
- Volunteers
- 92 people
- Sponsor
- Remedy Pharmaceuticals, Inc.
Lung Contusion
Lung Ultrasound Guided Fluid Balance Strategy in Patients with Lung Contusion
Lung contusion is caused by blunt chest trauma, explosion injuries or a shock wave associated with penetrating trauma. These injuries damage alveolar capillaries, so blood and other fluids accumulate in the lung tissue.
- Trial name
- NCT06586060
- Testing
- lung ultrasound guided fluid balance strategy, usual care guided fluid balance strategy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University