Clinical trials: Conversion
Mild Cognitive Impairment, Alzheimer's Disease
Multi-modality MRI Study on Prediction for Mild Cognitive Impairment Conversion
The purpose of this study is to find the characteristics of mild cognitive impairment (MCI) using technology of Multi-Modality MRI , including structural MRI, functional MRI and diffusion tensor imaging(DTI).
- Trial name
- NCT02353884
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- XuanwuH 2
Functional Movement Disorder
Study of Sensory Attenuation in Functional Movement Disorders
Functional movement disorders (FMD) are conditions where people experience unusual movements or difficulties with walking, not caused by a specific brain or nerve injury but related to how the brain controls movements.
- Trial name
- NCT06872788
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Metabolic Disease
Characterisation of the Human Carboxylesterase 1 (CES1) Mutations in Thailand
The aim of this study is to evaluate the conversion of OP to OC in individual X and the family member of individual X. The investigators hypothesize that one or more of the single nucleoprotein polymorphisms (SNPs) of the CES1…
- Trial name
- NCT01443806
- Testing
- Oseltamivir
- Where
- Thailand
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Laparoscopic Cholecystectomy in Children
Laparoscopic Cholecystectomy in Children. Risk Factors for Conversion. A Prospective Study .
Cholecystectomy is the most common procedure in biliary surgery which may be open or laparoscopic.laparoscopic cholecystectomy is widely accepted as the gold standard technique in both adults and children .over recent years there…
- Trial name
- NCT06048029
- Testing
- laparscopic Cholecystectomy in children
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Overweight, Hypercholesterolemia
Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in Humans
The objective of this study is to investigate the accumulation of n-3 LC-PUFA (EPA, DPA and DHA) in human lipids by oral supplementation of ALA-rich linseed oil.
- Trial name
- ALA_KK (NCT01317290)
- Testing
- n-3 PUFA free olive oil, linseed oil
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Jena
Globus Pharyngeus, Validation
The Validation of the Turkish Version of the LUMP Questionnaire
Purpose of the study is the validity and reliability of the Turkish version of the Laryngopharyngeal Measure of Perceived Sensation (T-LUMP) Questionnaire, so that it would be used as an assessment tool for Turkish globus…
- Trial name
- NCT04778007
- Testing
- Turkish Version of Laryngopharyngeal Measure of Perceived Sensation Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Poliomyelitis
Sero-conversion Study for a Two-dose Schedule of Sabin IPV in China
This study aims to obtain the direct domestic IPV vaccine monitoring data for the CNBG products, and provide scientific evidence for the National Immunization Program and long-term polio vaccine immunization policy.
- Trial name
- NCT03546634
- Testing
- Sabin IPV
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Physician's Role, Administration, Oral
Switching Medications From Intravenous to Oral
In a recent report, drug spending increased by 23.4 percent annually in the inpatient setting from 2013 to 2015 with the average inpatient drug spending increasing from $714 to $990 per admission.
- Trial name
- NCT03666520
- Testing
- Clinical Decision Support prompted to the clinician to convert drug.
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Educational Problems
PBP vs Traditional Training: the T-REC Trial
This randomized controlled trial aims to compare the effectiveness of traditional training approach to training with the proficiency-based progression (PBP) approach for teaching the technical skills (TS) and non-technical skills…
- Trial name
- T-REC (NCT06147128)
- Testing
- Emergency scenario in a simulated setting where open conversion is necessary due to vessel injury during robotic surgery on a dry lab model
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Orsi Academy
Parkinson Disease, Movement Disorder, Functional
The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls.
- Trial name
- NCT05800470
- Testing
- fNIRS-based neurofeedback with motor imagery, Kinesthetic motor imagery, Motor training
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cutaneous Leishmaniasis
Safety, False-Positive Reactions and Sensitizing Properties of Leishmania Tropica Skin Test Antigen
The efficacy of LtSTA as a skin test antigen depends upon the sensitivity and specificity of the product. This study has been designed to measure the skin test responses to 15, 30, or 50µg doses of LtSTA.
- Trial name
- NCT00633009
- Testing
- Leishmania tropica Skin Test Antigen (LtSTA)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nielsen BioSciences, Inc.
MCI, MCI Conversion to Dementia
Neurocognitive Assessment Platform 4 Alzheimer
The aging population in Europe is leading to an increase in neurodegenerative diseases, such as Alzheimer's disease (AD), which is expected to affect 152 million people worldwide by 2050.
- Conditions
- MCI, MCI Conversion to Dementia, AMCI - Amnestic Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NAP4A2020 (NCT07272811)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Schizophrenia Spectrum and Other Psychotic Disorders
Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia
Schizophrenia (SZ) is a highly debilitating neuropsychiatric disorder of young adulthood onset and a leading cause of disability worldwide.
- Trial name
- NCT03323437
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Healthy
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE)
The variation in extent of isothiocyanate (ITC) excretion in urine from a capsule delivered dose of glucoraphanin will correlate with differences in (a) the gut microbiota, and (b) the genotype of key polymorphic genes (GSTM1…
- Trial name
- ENGAGE (NCT01927666)
- Testing
- 100mg glucoraphanin
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Healthy
Provitamin A Absorption and Conversion With Avocados
Vitamin A is necessary in the human diet. The form of vitamin A found in fruits and vegetables is not "active" and must be converted to the active form in the human body.
- Trial name
- NCT01432210
- Testing
- Post-prandial Feeding Study
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cardiovascular Diseases in Old Age
Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion
The objective of this study was to determine the chronic effects of beetroot juice supplementation on the acute (90-minute post nitrate consumption) efficacy of converting dietary nitrate to plasma nitrate and plasma nitrite in…
- Trial name
- NCT05380167
- Testing
- BRJ Nitrate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
BCG Vaccination Reaction
Safety and Tuberculin Conversion Following BCG Vaccination
The study is an bridging study, observer-blind, randomized, controlled prospective intervention study. The primary objective is evaluate the safety of BCG Vaccine Vial (Bio Farma).
- Trial name
- NCT05124340
- Testing
- BCG vial vaccine, BCG ampoule vaccine
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Functional Movement Disorder
Passive Thoughts in Functional Movement Disorders
Passive thoughts also known as mind-wandering are the thoughts that are not produced from the current task. When we aren't focused on a task that needs our full attention, our minds tend to drift from one thought to another.
- Trial name
- NCT06439017
- Testing
- Questionaire
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Western University, Canada