Clinical trials: Cor Pulmonale
Cardiopulmonary Disease
Effects of Secondhand Smoke on Flight Attendant Health
This is a study on a population of flight attendants who were exposed to occupational secondhand tobacco smoke (SHS). This research will examine associations between flight attendant SHS exposure and development of respiratory…
- Trial name
- FAMRI (NCT01639235)
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sickle Cell Anemia
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine longitudinal changes in exercise capacity over a 2 year period in children and young adults with sickle cell anemia.
- Trial name
- NCT01558076
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN
Cardiopulmonary Disease
SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.
Increasingly, transesophageal echos (TEEs) are being done on high risk patients. A TEE is a short procedure done with deep sedation, but poses an increased risk of apnea/ hypoxemia in those with pulmonary disease.
- Trial name
- SGA-TEE (NCT04939220)
- Testing
- TEE with SGA, TEE with Deep Sedation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Cardiopulmonary Disease
Respiration Validation for CPM Device
This study is designed to be a clinical validation study to ready the CPM System for FDA 510(k) submission. This study will be conducted as a prospective non-randomized.
- Trial name
- NCT05445492
- Testing
- CPM Device
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Analog Device, Inc.
Pulmonary Hypertension, Right Heart Failure Due to Pulmonary Hypertension
Postural Changes During Right Heart Catheterization
Hemodynamic measurements obtained during pulmonary artery catheterization are essential for the diagnosis and classification of pulmonary hypertension.
- Trial name
- NCT03089164
- Testing
- Right heart catheterization
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cardiopulmonary Disease
Clinical Validation Study for Noninvasive Cardiopulmonary Management Device
The ADI At-Home CPM (Cardiopulmonary Management) System is a non-invasive device that measures and trends a variety of biological parameters.
- Trial name
- NCT04865640
- Testing
- Noninterventional and noninvasive
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Analog Device, Inc.
Chronic Lung Disease, Cardiopulmonary Disease
Exercise Strategies to Motivate and Relieve Stress
The goal of this clinical trial is to evaluate exercise strategies that motivate and relive stress in adults with cardiopulomnary conditions.
- Trial name
- NCT05776264
- Testing
- Music Condition, Podcast Condition
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Columbia University
Heart Failure, Chronic Obstructive Pulmonary Disease
Metabolic Changes in Patients With Chronic Cardiopulmonary Disease
This study aims to evaluate prevalence of sarcopenia and cachexia in patients with chronic cardiopulmonary disease. The investigators will also investigate metabolic disorders like glucose metabolism, presence of metabolic…
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Malignancy, Chronic Kidney Disease
- Trial name
- NCT02550808
- Where
- Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- General and Teaching Hospital Celje
Eccentric Cycling Exercise Training
Effectiveness of Eccentric Cycling Exercise in Ambulatory Rehabilitation for Patients With Cardiopulmonary Diseases: A Pragmatic Randomized Controlled Trial
In eccentric cycling exercise (ECC), the cyclist must oppose backwards moving pedals on a specialized motor-driven ergometer. Throughout this process, the force applied on the pedals exceeds the torque generated by the…
- Trial name
- NCT07815366
- Testing
- Eccentric cycling exercise
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cardiopulmonary Disease
Indoor Air and Children Health Study
The objective of this study is to investigate the cardiopulmonary health effects of indoor air purification and different indoor environmental factors among school students in Beijing.
- Trial name
- NCT03319056
- Testing
- Air purifier
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking University
Cardiopulmonary Disease
Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases
Researchers are trying to develop innovative strategies that target the early identification heart and lung imbalances in patients with cardiopulmonary diseases.
- Trial name
- NCT03911856
- Testing
- Echocardiography, Pulmonary Gas Exchange
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiopulmonary Diseases
Indoor Air Filtration and Young Adults Health Study
This study aims to explore the cardiopulmonary health effects of indoor air purification and other indoor environmental conditions among young healthy college students in Beijing, China.
- Trial name
- NCT05172388
- Testing
- Air purifier
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Peking University
Sickle Cell Anemia
Exercise Capacity in Pediatric Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine causes of exercise limitation in children and young adults with sickle cell anemia.
- Trial name
- NCT01527799
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Sleep Disordered Breathing, Sleep Apnea
Sleep Disordered Breathing and Cardiopulmonary Disease in Peruvian Highlanders
Overall objective: To understand the feasibility of performing a randomized trial using a simple, minimally-invasive postural therapy approach to improve sleep disordered breathing (SDB).
- Trial name
- NCT03927547
- Testing
- Inclined Sleep
- Where
- Peru
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Respiratory Tract Diseases, Cardiac Diseases
Cardiopulmonary Effects of Particulate Exposure
The aim of this study is to assess cardiac rate and respiratory responses and rhythm after workplace exposure to combustion particulates.
- Conditions
- Respiratory Tract Diseases, Cardiac Diseases, Bronchitis
- Trial name
- NCT00011310
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Outpatients, Cardiology
Interpretation Performance in Chinese and Japanese Medical Consultation Scenarios
This study aims to compare the translation and interpretation performance of ChatGPT, Google Translate(GT),and UD Talk in cardiopulmonary consultations and analyze their effectiveness in addressing language barriers.The…
- Conditions
- Outpatients, Cardiology, Pulmonology
- Trial name
- NCT06934031
- Testing
- translation software
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction
Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in volunteers with PH in the breakdown of oral nitrate and effect on hemodynamics.
- Conditions
- Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction, Pulmonary Heart Disease and Diseases of Pulmonary Circulation
- Trial name
- NCT03787082
- Testing
- Nitrates, Chlorhexidine Gluconate Mouthwash
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gladwin, Mark, MD