Clinical trials: Corneal Parameters
Tomography
UNITY DX Cornea Study
The purpose of this study is to validate the clinical measurement performance of an investigational biometer. Subjects will undergo multiple measurements of the eye, and the agreement, repeatability, and reproducibility of…
- Trial name
- NCT07768735
- Testing
- UNITY DX, ANTERION
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Corneal Sensation Reduced, Corneal Dystrophy
Defining the Operating Parameters for a Rebound-esthesiometer
The purpose of this study is to define the operating parameters for a new method to measure corneal sensitivity.
- Conditions
- Corneal Sensation Reduced, Corneal Dystrophy, Corneal Degeneration, Corneal Transplant Failure
- Trial name
- NCT04384094
- Testing
- Esthesiometer measurement
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Corneal Biomechanics
Evaluation of the Change in the DA Ratio, IR and SSI as Parameters of Corneal Biomechanics Post Different LVC Procedures
In the study, The Investigators will compare the participates' corneal biomechanical properties including: Deformation Amplitude ratio (Da Ratio) Integrated Radius (IR) Stress strain index (SSI) All measurements will be taken…
- Trial name
- NCT05377099
- Testing
- CORVIS
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cairo University
Keratoconus
Objective and Subjective Diagnostic Parameters in the Fellow Eye of Unilateral Keratoconus
patients with keratoconus in one eye and forme fruste keratoconus in the fellow eye compared to normal subjects .the patients were examined by schemipflug imaging system (Pentacam)
- Trial name
- NCT03288116
- Testing
- Scheimplug imaging and contrast and sensitivity test
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dar Al Shifa Hospital
Scansys, Pentacam, Keratoconus, Subclinical Keratoconus
Evolution of a Novel Optical Coherence Tomography Based Index in Diagnosing Keratoconus
Comparison of corneal topography based on oct OCT principle (CASIA2) with Pentacam and Scheimpflug-based biomechanical devices (Corvis ST) in screening and diagnosing keratoconus; and evaluation of the consistency with Pentacam…
- Trial name
- NCT06152484
- Testing
- Pentacam, Corvis ST and CASIA2
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Corneal Parameters
Measuring Corneal Parameters
The aim of this clinical investigation is to assess the feasibility of the investigational device for measuring corneal parameters of the human eye.
- Trial name
- NCT07629232
- Testing
- Investigational device, Comparator device
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Ectasia
Eye Rubbing and Transient Change in Corneal Parameters
This study addresses the research question: How does eye rubbing affect corneal (clear part of eye) parameters in healthy volunteers The study objectives are: 1. To determine the corneal changes following eye rubbing 2.
- Trial name
- NCT02131740
- Testing
- Eye rubbing, No eye rubbing
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sussex Eye Hospital
Smoking ( Cigarette), Cornea
Acute Ocular Effects of Cigarette Smoking
This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults.
- Conditions
- Smoking ( Cigarette), Cornea, Anterior Eye Segment Measurements
- Trial name
- NCT07580040
- Testing
- Cigarette Smoking Exposure, No Smoking Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Sjogren's Syndrome, Dry Eye
Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye
In this study the investigators plan to enroll three groups of patients: non-Sjogren's dry eye, Sjogren's dry eye and controls. The study has the following primary goals: 1.
- Conditions
- Sjogren's Syndrome, Dry Eye, Neurotrophic Keratitis
- Trial name
- IIR (NCT06364657)
- Testing
- Eye Exam
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hydration Status, Macular Thickness
Hydration Status and Ocular Parameters Study
This study will examine how hydration status (drinking a large amount of water or avoiding water for a short period of time) affects the eye.
- Conditions
- Hydration Status, Macular Thickness, Ocular Biometry
- Trial name
- HYDRI-EYE (NCT07177131)
- Testing
- Relative Dehydration Protocol, Hyperhydration Protocol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ante Kreso
Keratoconus, Corneal Ectasia
Corneal Tomographic Parameters in TGD
The current study involved analysis of the corneal tomographic parameters of patients with thyroid gland dysfunction (hyperthyroidism or hypothyroidism), including those with an autoimmune etiology, in comparison to healthy…
- Conditions
- Keratoconus, Corneal Ectasia, Thyroid Eye Disease
- Trial name
- NCT04433936
- Testing
- Pentacam tomography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ameera Gamal Abdelhameed
Polycystic Ovary Syndrome
Ocular Findings of Polycystic Ovary Syndrome
Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy…
- Trial name
- NCT03896841
- Testing
- Observation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Glaucoma
The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.
The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared.
- Trial name
- NCT06340061
- Testing
- Observational study
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Keratoconus
Assessment of Corneal Stiffness in Keratoconus After Crosslinking by Corvis ST and OCT.
Objectives: Measurement of corneal stiffness parameters { Deformation Amlitude (DAR1), Integrated radius, Stress parameter (SP A1), Stress strain index (SSI) and Corvis biomechanical index (CBI) } in keratoconic corneas before…
- Trial name
- NCT05161052
- Testing
- Corvis ST (dynamic Scheimpflug technology)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pseudoexfoliation Syndrome, Biomechanical Parameters
Corneal Biomechanics, Optical Properties and Anterior Segment Structural Features in Patients With Pseudoexfoliation
The purpose of this study is to assess the effect of pseudoexfoliation syndrome on corneal biomechanics, optical clarity of the cornea, and anterior segment structural features.
- Conditions
- Pseudoexfoliation Syndrome, Biomechanical Parameters, Corneal Densitometry
- Trial name
- CorPEX (NCT06731530)
- Testing
- Pentacam-AXL, HD Analyzer, Corvis ST
- Where
- Greece
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pregnancy Related
Comparing Anterior Segment Parameters During Pregnancy and Post-Pregnancy
The aim of this study is to evaluate anterior segment changes during and after pregnancy, and compare them with non pregnant healty women
- Trial name
- NCT05175729
- Testing
- Comprehensive Ophthalmologic Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University