Clinical trials: Corneal Topography
Keratoconjunctivitis
Corneal Topography in Vernal Keratoconjunctivitis
To evaluate the corneal topographic changes in VKC patients using Pentacam and prevalence of KC development in VKC.
- Trial name
- NCT06746467
- Testing
- pentacam
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Keratoconus
Validation of Innovative Scheimpflug Topography Derived RGP Contact Lens Designs In Optometry Network
The goal of this Prospective, single-site, cohort study is to validate rigid gas permeable corneal contact lens (RGP) designs for keratoconus derived from combining the data from corneal topography scans and contact lenses…
- Trial name
- VISION (NCT06312163)
- Testing
- The contact lens to be investigated in this study (Scheimpflug topography derived corneal RGP contact lens design). A CE (UKCA) marked class 2 medical devices.
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Cataract
Zeiss® IOLMaster 700 Corneal Topography Module Comparison With Schwind's Sirius Corneal Topography®
In order to determine the intraocular lens to be implanted during cataract surgery, keratometry and axial length must be measured in preoperative. The axial length is obtained by ocular ultrasound mode B.
- Trial name
- VIMECT (NCT05414773)
- Testing
- measurement of axial length and keratometry by sonographers with a topographic module
- Volunteers
- 100 people
- Sponsor
- Edouard KOCH
Keratoconus
Astigmatic Vector Analysis of Posterior Cornea - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas
The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.
- Trial name
- NCT02698709
- Testing
- Analysis of anterior and posterior corneal surfaces
- Where
- Brazil
- Volunteers
- 698 people
- Sponsor
- University of Sao Paulo
Corneal Opacity
Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze
This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner.
- Trial name
- NCT00439114
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baskent University
Evaluation of Corneal Stability Post-applanation
Icare Tonometry Effects on Keratometry Readings, Topography Readings, and Corneal Staining
To demonstrate that the Icare tonometer does not alter Keratometry readings, topography, or corneal staining. This would therefore allow intraocular pressure (IOP) testing to be done at any time during an exam, without affecting…
- Trial name
- NCT03275142
- Testing
- Icare tonometer
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Comprehensive EyeCare of Central Ohio
Disorders, Refractive
Comparison of Corneal Stromal Tissue Consumption (LATAC)
In refractive surgery, stromal ablation depth is fundamental because it determines the thickness of the residual posterior wall.
- Trial name
- LATAC (NCT02519673)
- Testing
- Measurement of stromal tissue ablation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Healthy
A Clinical Evaluation of the Next Generation Diagnostic Instrument (NGDI)
The purpose of this study is to measure the aberrations, corneal surface topography and pachymetry of normal human eyes with the NGDI.
- Trial name
- NCT00347594
- Testing
- Next Generation Diagnostic Instrument (NGDI), Zyoptix Diagnostic Workstation (ZDW)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Keratoconus
Topography Versus Non-Topography-Guided PRK With CXL in Keratoconus
To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL)…
- Trial name
- keratoconus (NCT03890718)
- Testing
- Photorefractive keratectomy in mile keratoconus
- Where
- Iran
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Corneal Topography
Comparison Between Bare Scleral Technique and Conjunctival Auto-graft on Corneal Topography After Pterygium Surgery
Aim of the work: To study the corneal topographic pattern changes in patients who have pterygium excision by two surgical techniques (bare sclera, conjunctival autograft).
- Trial name
- NCT05812508
- Testing
- corneal topography
- Volunteers
- 30 people
- Sponsor
- Sohag University
Cataract
Clinical Study - ES 900 - 2020-1
EYESTAR 900 is a device developed by Haag-Streit which utilises 3D OCT for quantitative measurements of the geometry of the entire eye, including ocular biometry and corneal topography.
- Trial name
- NCT05304182
- Testing
- EYESTAR 900, LENSTAR LS 900
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Haag-Streit AG
Keratoconus, Keratoconus, Artificial Intelligence, Support Vector Machine
Predicting Manifest Astigmatism in Keratoconus Patients.
The cornea of the human eye has several functions. It is transparent to allow light into the eye and its shape focuses the incoming light onto the retina.
- Trial name
- NCT06798779
- Testing
- Glasses, Corneal topography
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Keratoconus, Pellucid Marginal Degeneration
T-Cat Laser & Cross-linking for Keratoconus
The purpose of this study is to determine whether excimer laser corneal surface ablation (T-Cat) can be safely combined with simultaneous corneal collagen cross-linking treatment to produce an improved and stable corneal profile…
- Trial name
- T-Cat (NCT00777322)
- Testing
- Excimer laser ablation, and collagen cross-linking
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Corneal Topography, Dry Eye Syndromes
Performance Evaluation of the OCUTOP Hand-held Corneal Topographer
The OCUTOP is a new hand-held camera that photographs the front of the eye to map the shape of the cornea and to assess the tear film.
- Conditions
- Corneal Topography, Dry Eye Syndromes, Keratoconus, Healthy Volunteers
- Trial name
- OCUTOP (NCT07895849)
- Testing
- OCUTOP hand-held corneal topographer with OCUGRAPH software, Reference instrument measurement (corneal topography and tear-film assessment)
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Keratoconus, Keratoconus, Unspecified, Bilateral
Evaluation of Tomographic and Genetic Aspects of Keratoconus Patients Compared to Sounds Corneas
Evaluation of tomographic (Pentacam) parameters and genetic parameters of Visual System Homeobox 1 (VSX1), Superoxide Dismutase (SOD1), Tissue Inhibitors of Metalloproteinases (TIMP3) genes of keratoconus patients diagnosed by…
- Trial name
- NCT03071302
- Testing
- EVALUATION OF VSX1, SOD1, and TIMP3 genes
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Sao Jose do Rio Preto Medical School
Keratoconus, Alteration of Visual Acuity
CHOICE OF SUBJECTIVE OCULAR REFRACTION TECHNIQUE AND CORNEAL TOPOGRAPHY OF KERATOCONUS
Keratoconus is a rare evolving corneal ectasia that alters visual acuity. To improve spectacle-corrected visual acuity, various subjective refraction techniques can be used.
- Trial name
- RE-CON (NCT04174209)
- Testing
- Cylinder, Dial, Slit
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Influence of Artificial Tears on Keratometry and Biometry Measurements With Different Devices
The goal of this clinical trial is to learn about the influence of artificial tears on measurements of healthy eyes with three different devices.
- Trial name
- NCT06358456
- Testing
- Artificial tear, No artificial tears
- Where
- Germany
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Keratoconus
A Clinical Study of Keratoconus in Asian Patients and Assessment of Different Topographic Patterns of Keratoconus in Asian Patients
A clinical study of keratoconus in Asian Patients and assessment of different topographic patterns of keratoconus in Asian patients
- Trial name
- NCT00347074
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Cataract, Refractive Surgery
Refractive Change Induced by 2.8-mm Corneal Incision
The investigators' purpose is to study the induced refractive change caused by different 2.8-mm corneal incision locations in phacoemulsification, because the investigators hypothesize that the effect may be different for nasal…
- Conditions
- Cataract, Refractive Surgery, Astigmatism
- Trial name
- CINPHA (NCT00742950)
- Testing
- Nasal 2.8-mm corneal incision, Temporal 2.8-mm corneal incision, Superior 2.8-mm incision
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Universitario Ramon y Cajal