Clinical trials: Coronary Artery Bypass Surgery
Delirium on Emergence
Efficacy of Dexmedetomidine Versus Clonidine to Control Delirium in Patients Undergoing CABG
This prospective, randomised, double blinded, controlled clinical trial will be conducted in 147 patients between 60 yr and 70 yr , ASA physical status II and III, undergoing CABG.
- Trial name
- NCT03477994
- Testing
- Dexmedetomidine, Clonidine
- Where
- Egypt
- Volunteers
- 147 people
- Sponsor
- Ain Shams University
Chronic Ischemic Heart Disease, Obesity
Results of Coronary Artery Bypass Grafting in Obese Patients
This study is planned to assess the effect of obesity (BMI over 30 kg / m2) on hospital outcomes of isolated coronary artery bypass grafting in patients with chronic ischemic heart disease.
- Trial name
- NCT04916912
- Testing
- coronary artery bypass grafting
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Ischemic Heart Disease
Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG
ADR-002K is administered to heart failure patients with ischemic heart disease who undergo coronary artery bypass surgery (CABG) to investigate its efficacy and safety.
- Trial name
- NCT07192211
- Testing
- Mesenchymal stem cell
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Rohto Pharmaceutical Co., Ltd.
Coronary Artery Disease
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
This is a research study in women to compare the outcomes of two procedures that restore blood flow to the arteries of the heart.
- Trial name
- RECHARGE:W (NCT06399692)
- Testing
- Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI)
- Where
- 18 sites in United States
- Volunteers
- 600 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Bypass Grafting, Acute Normovolemic Hemodilution
Hemodynamic Management in Autologous Blood Collection for CABG Surgery
In this study, investigated the hemodynamic differences between patients who underwent acute normovolemic hemodilution during the Autologous Blood Collection procedure in coronary artery bypass graft surgery and those who did…
- Trial name
- NCT06835257
- Testing
- Acute normovolemic hemodilutions, Vasopressor infusion
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, ICU Hospitalization
The Effect of Parasternal Block on Postoperative Pain in Patients Undergoing Coronary Artery Bypass Graft Surgery
Objective: This study aims to investigate the effects of intraoperative parasternal block on postoperative analgesia in patients undergoing elective coronary artery bypass graft surgery.
- Conditions
- Postoperative Pain, ICU Hospitalization, Extubation Time
- Trial name
- NCT06893601
- Testing
- Parasternal block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Cardiovascular Diseases
The Impact of Altered Arterioventricular Coupling on Central Cardiovascular Energy Delivery
This study will assess the amount of energy that the heart will deliver to the central circulation and the efficiency of that energy transfer, in patients undergoing a coronary artery bypass graft operation.
- Trial name
- NCT03656757
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Norwegian University of Science and Technology
Coronary Artery Bypass Surgery, Right-Sided Heart Failure
The SWEDEGRAFT Right-Heart-Substudy
BACKGROUND Right ventricular dysfunction is a common echocardiographic finding after cardiac surgery. Pericardial disruption has been suggested as the most probable cause as the phenomenon occurs within minutes after pericardial…
- Trial name
- NCT05049421
- Testing
- Echocardiography
- Where
- Denmark
- Volunteers
- 207 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Vascularization
Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery
Heart disease is the leading cause of death globally, accounting for 16% of the world's total deaths. The number of cases is expected to increase as our population ages. Heart disease also results in large economic burden.
- Trial name
- ACT for CABG (NCT06207318)
- Testing
- Acceptance and commitment therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Iowa
Atrial Fibrillation
Effect of Prophylaxy of Amiodarone and Propranolol and Amiodarone With Propranolol in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft
Atrial fibrillation is the most common arrhythmia post coronary bypass surgery, currently B-blockers are the class I indication to prevent AF post CABG.
- Trial name
- NCT00654290
- Testing
- Amiodarone + Propranolol, Amiodarone, Propranolol
- Where
- Iran
- Volunteers
- 240 people
- Sponsor
- Shiraz University of Medical Sciences
Cardiac Surgery
Optimal Timing of Coronary Artery Bypass Grafting in Hemodynamically Stable Patient After Myocardial Infarction and Definition of Poor Prognostic Factors. Pilot Study
Acute coronary syndromes (ACS) represent the leading cause of death in France. Their incidence is increasing due to population aging and to the persistence of cardiovascular risk factors.
- Trial name
- NCT03863158
- Testing
- No intervention
- Volunteers
- 476 people
- Sponsor
- Centre Hospitalier La Chartreuse
Fluid Responsiveness
Combination of Static Echocardiographic Indices for Prediction of Fluid Responsiveness During Cardiac Surgery
In the perioperative or critical care of hemodynamically unstable patients, appropriate fluid resuscitation guided by reliable preload indices is of pivotal importance as only half of them are fluid responsive, and that empiric…
- Trial name
- NCT03222778
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Coronary Artery Bypass Grafting
Arrested Versus Beating Heart Techniques in Coronary Revascularisation
The individual contribution of the specific injuring mechanisms surgical trauma, extracorporeal circulation, and ischemia/reperfusion to clinical outcome in coronary revascularisation remains to be elucidated.
- Trial name
- NCT00999089
- Testing
- Conventional Coronary Artery Bypass, Off-Pump Coronary Artery Bypass, Pump-Assisted Coronary Artery Bypass
- Where
- 2 sites in Germany
- Volunteers
- 616 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Coronary Artery Disease (CAD);, Myocardial Infarction (MI)
A Multicentre Trial on the Effectiveness of Physical Rehabilitation of Patients With Coronary Artery Disease: Aerobic Interval Training Versus Moderate Continuous Training.
Cardiac rehabilitation, including physical training, has become accepted treatment following myocardial infarction, coronary stent implantation and coronary bypass operation.
- Conditions
- Coronary Artery Disease (CAD);, Myocardial Infarction (MI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Grafting (CABG)
- Trial name
- SAINTEX-CAD (NCT01226225)
- Testing
- Aerobic interval training, Moderate endurance training
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Lung Injury, Pulmonary Complication
Intra-operative Fraction of Inspired Oxygen and Lung Injury in Coronary Artery Bypass Grafting Surgery
This study is a prospective observer blinded, central randomization controlled, multi-center clinical trial to assess the relationship between intraoperative FiO2 and postoperative pulmonary complications with lung injury.
- Trial name
- NCT04115501
- Testing
- Fraction of Inspired Oxygen
- Where
- United States
- Sponsor
- University of Louisville
Coronary Artery Bypass Grafting, Secondary Preventions
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Secondary Prevention
The investigators have identified underuse of secondary prevention medications at discharge of patients underwent coronary artery bypass grafting (CABG) in China.
- Trial name
- MISSION-1 (NCT02430012)
- Testing
- Quality improvement strategies
- Where
- China
- Volunteers
- 10,009 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Graft Surgery
Vitamin C in Cardiac Surgery Patients
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery that increases the incidence of stroke, kidney injury and death.
- Trial name
- NCT03123107
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Geisinger Clinic
Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD)
The Effect of Neuromuscular Electrical Stimulation
The effect of neuromuscular electrical stimulation on muscle atrophy in sedated patients on intensive care was studied. The aim of this study was to explore if electrical stimulation could prevent muscle atrophy.
- Conditions
- Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD), Ventilatory Failure
- Trial name
- NCT00442728
- Testing
- ELECTRICAL STIMULATION
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Provinciale Hogeschool Limburg
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