Clinical trials: Coronary Bifurcation Lesion
Coronary Artery Disease
Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
This study is a prospective, randomized, single-center evaluation of the Cypher™ Sirolimus eluting coronary stent system in the treatment of de novo bifurcated coronary lesions comparing provisional modified T stenting with…
- Trial name
- NCT00288535
- Testing
- PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Artery Disease, Bifurcation Lesion
Using 3D Imaging to Optimize Bifurcation Stenting
The primary purpose of this study is to determine whether bifurcation stenting guided by on-line three-dimensional optical frequency domain imaging (3D-OFDI) is superior to that with angiographic guidance by measuring incomplete…
- Trial name
- NCT02972489
- Testing
- 3D OFDI guidance arm, Angio guidance arm
- Where
- 2 sites in Japan, Netherlands
- Volunteers
- 106 people
- Sponsor
- Increase Co., Ltd.
Coronary Artery Disease
H-Side Branch Stent, A New Stent for the Treatment of True Bifurcation Lesions
Intervention for coronary bifurcation lesion is about 10~20% of entire percutaneous coronary intervention (PCI). Bifurcation lesion is difficult to be treated and prognosis of PCI at bifurcation lesion has been poorer compared to…
- Trial name
- NCT02037386
- Testing
- H-side branch stent
- Sponsor
- Yonsei University
Coronary Artery Disease, Coronary Artery Disease (Left Main)
µQFR for Branch Stenosis After Single Stent in Bifurcation Lesions
Murray-law based single-view quantitative flow ratio (µQFR) has been recommended for guiding percutaneous coronary intervention (PCI) in selective patients.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease (Left Main), Obstructive Coronary Artery Disease, Stent Implantation
- Trial name
- NCT07116083
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Shanghai Zhongshan Hospital
Safety Issues, Efficacy, Self
Lower Silesia Culotte Bifurcation Registry (LSCBR).
The study aimed to evaluate the outcomes of bifurcation PCI using two techniques (Culotte vs. DK-Culotte) using data from a retrospective analysis.
- Trial name
- LSCBR (NCT06284057)
- Testing
- Bifurcation PCI with two stent technique Culotte Technique or Double Kiss (DK) Culotte
- Where
- 2 sites in Poland
- Volunteers
- 400 people
- Sponsor
- Miedziowe Centrum Zdrowia SA
Coronary Artery Disease
The BIFSORB Pilot Study II
The purpose of this study is to investigate the feasibility and safety of the Magmaris BRS for treatment of coronary bifurcation lesions.
- Trial name
- BIFSORB P-II (NCT03027856)
- Testing
- Magmaris
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease
Bingo Drug-eluting Balloon Versus a Drug-eluting Stent for Coronary Bifurcation Lesions
Bingo drug-eluting balloon versus a drug-eluting stent for coronary bifurcation lesions: a prospective, multi-center, randomized, non-inferiority trial
- Trial name
- NCT06441539
- Testing
- Bingo® Paclitaxel coated balloon, Xience® Alpine Everolimus Eluting Coronary Stent System
- Volunteers
- 218 people
- Sponsor
- Yinyi(Liaoning) Biotech Co., Ltd.
Percutaneous Coronary Intervention
Short Term and Long Term Effects of Single Stent and Embedded Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesions
At the same time in the side branch stent expansion vessels were embedded and balloon dilatation technique in for Medina1.1.1 type, 1.0.1 type or 0.1.1 type lesions of interventional therapy for bifurcation lesions, the PCI…
- Trial name
- NCT02691819
- Testing
- single stent and embedded balloon angioplasty
- Where
- China
- Volunteers
- 60 people
- Sponsor
- ZhangWenduo
Percutaneous Transluminal Coronary Angioplasty, Coronary Artery Disease
The European Bifurcation Club Left Main Study
The objective of the study is to investigate clinical outcomes following single versus dual stenting strategies for the treatment of true bifurcation distal left main coronary artery lesions.
- Trial name
- EBC MAIN (NCT02497014)
- Testing
- 1 Stent, 2 Stents
- Where
- 24 sites in Denmark, France and 6 more
- Volunteers
- 450 people
- Sponsor
- European Cardiovascular Research Center
Coronary Artery Disease
Balloon-Stent Kissing Technique Versus Jailed Wire Technique for the Coronary Bifurcation Lesions
To compare the immediate and long-term clinical outcomes between Balloon-Stent Kissing Technique (BSKT) and Jailed Wire Technique (JWT) for the interventional treatment of coronary bifurcation lesions.
- Trial name
- NCT03429634
- Testing
- Balloon-Stent Kissing technique, Jailed Wire technique
- Where
- China
- Volunteers
- 89 people
- Sponsor
- Dalian University
Coronary Artery Disease
Modified T-Stenting With Szabo Technique Versus T-Stenting for Bifurcation Lesions in Coronary Heart Diseases
The study will compare clinical outcomes of modified T-stenting with Szabo technique with T-stenting for bifurcation lesions in coronary heart diseases.
- Trial name
- NCT03714802
- Testing
- Szabo T-Stenting Technique, T-Stenting Technique
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease, Bifurcation Lesions
Efficacy Study of Kissing Drug-Eluting Balloons in Coronary Bifurcation Lesions
KISSING DEBBIE's aim at assessing angiographic and clinical outcomes of provisional treatment of coronary bifurca6on lesions according to TAP sten6ng with BMS and final kissing DEB
- Trial name
- KISSING DEBBIE (NCT01009996)
- Testing
- Kissing DEB
- Where
- Italy
- Sponsor
- Ospedale Santa Maria Goretti
Coronary Ostium Stenosis, Myonecrosis
Side Branch Predilatation Strategy in Coronary Bifurcation Lesion Stenting (SBPS)
The role of Side Branch (SB) predilatation during coronary bifurcation lesion percutaneous coronary intervention (PCI) is still not established.
- Trial name
- SBPS (NCT01430377)
- Testing
- SB predilatation, No SB predilatation
- Where
- Bulgaria
- Volunteers
- 120 people
- Sponsor
- Medica Cor Heart Hospital
Coronary Disease
European Bifurcation Club Trial - Two-stent Versus One-stent Technique for Large Bifurcation Lesions
This study will examine use of two-stent versus one-stent techniques for patients with large calibre bifurcation lesions including significant side branch disease.
- Trial name
- EBC TWO (NCT01560455)
- Testing
- single stent, two stent
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Sussex County Hospital
Coronary Disease
"L-Sandwich" Strategy in the True Coronary Bifurcation Lesions
The treatment of coronary bifurcation lesions continue to remain challenges. Due to the complexity of the anatomical structure and the limitations of imaging, there are poor attachment and under-expansion of the stent at the…
- Trial name
- L-Sandwich (NCT04753827)
- Testing
- Drug eluting stent, Durg coated balloon
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Coronary Atherosclerosis
Bifurcation Lesion Analysis and STenting / BLAST
The purpose of this research study is to determine if Intravascular Ultrasound (IVUS) grayscale and VH (Virtual Histology)-IVUS pre-stenting can assess more accurately the location, amount, and type of a blockage than angiogram…
- Trial name
- BLAST (NCT02316782)
- Testing
- Blinded IVUS assessment, Nonblinded IVUS
- Where
- 10 sites in United States, Denmark and 6 more
- Volunteers
- 195 people
- Sponsor
- Volcano Corporation
Coronary Heart Disease
The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions
A Prospective Multi-center Randomized Trial Assessing the Efficacy and Safety of Active Transfer of Plaque vs. Provisional T Stenting for the Treatment of Non-Left-Main Coronary Bifurcation Lesions.
- Trial name
- NCT02768116
- Testing
- Sirolimus Drug-eluting Stent via Active Transfer of Plaque, Sirolimus Drug-eluting Stent implantation via Provisional T Stenting
- Volunteers
- 316 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Angiography
Predilation of Side Branch During Percutaneous Treatment of Bifurcation Lesions With Provisional T Stenting
Percutaneous treatment of bifurcation lesion is a complex procedure. After main vessel stent implantation, the side branch became jailed and the carina can be displaced resulting in complete occlusion of this vessel.
- Trial name
- NCT01090856
- Testing
- Pre-dilation side branch
- Where
- Spain
- Volunteers
- 420 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Coronary Artery Disease
Tryton Post Approval Study (PAS) for the Tryton Side Branch Stent
TRYTON Post Approval Study (PAS) of the Tryton Side Branch Stent
- Trial name
- PAS (NCT03318796)
- Testing
- Coronary Artery Stenting
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Tryton Medical, Inc.
Coronary Artery Disease, Myocardial Ischemia
AngioSculpt® Coronary Bifurcation Study
The purpose of this study is to evaluate a new angioplasty catheter, AngioSculpt® for the treatment of bifurcation lesions (blockages occurring at branch points) in coronary arteries.
- Trial name
- AGILITY (NCT00686647)
- Testing
- AngioSculpt® Scoring Balloon Catheter, AngioSculpt Scoring Balloon Catheter
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- AngioScore, Inc.