Clinical trials: Coronary Ectasia
Coronary Artery Disease, Coronary Artery Ectasia
Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck…
- Conditions
- Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction
- Trial name
- STRAIN-TIMI (NCT02831153)
- Testing
- coronary angiography
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ertan YETKIN
Cardiac Arrest, Post-Anoxic Coma
Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest
Two-thirds of patients admitted to the Intensive Care Unit after a cardiac arrest die in the context of treatment withdrawal after a multimodal evaluation that determines an unfavorable neurological outcome.
- Conditions
- Cardiac Arrest, Post-Anoxic Coma, Anoxic Brain Injury
- Trial name
- CAPPI (NCT04336930)
- Testing
- Pupillary pain index (PPI)
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease (CAD), Ischemic Heart Disease
NC Xperience PMCF Study( rEPIC04B)
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of NC Xperience to meet EU Medical Device regulation (MDR) requirements in all the…
- Trial name
- rEPIC04B (NCT05292105)
- Testing
- NC Xperience
- Where
- 3 sites in Spain
- Volunteers
- 59 people
- Sponsor
- Fundación EPIC
Coronary Artery Disease, Coronary Disease
Sapphire II PRO US Clinical Study
A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device procedural success of the Sapphire II PRO 1.0 and 1.25 mm PTCA dilatation catheters in subjects with…
- Conditions
- Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Heart Diseases
- Trial name
- NCT03052530
- Testing
- Sapphire II PRO
- Where
- 4 sites in United States
- Volunteers
- 61 people
- Sponsor
- OrbusNeich
Coronary Microvascular Dysfunction
A Plant-Based Diet in the Treatment of Coronary Microvascular Dysfunction
This study will evaluate whether a fully provided, unrefined, polyphenol-rich plant-based diet can improve blood vessel function in adults with coronary microvascular dysfunction (CMD), a condition that causes reduced blood flow…
- Trial name
- NCT07821372
- Testing
- Polyphenol-Rich Plant-Based Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Hypertension, Hypertrophy, Left Ventricular
Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
The presence of Left ventricular hypertrophy (LVH) confers high cardiovascular risk in hypertensive patients. LVH remains highly prevalent even when blood pressure (BP) is controlled.
- Trial name
- ALLAY (NCT02237339)
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Dundee
Aortic Stenosis, Ascending Aortic Dilatation
Efficacy of Self-expandable and Balloon-expandable Valves in Patients With Ascending Aortic Dilation
This study evaluated the efficacy of self-expandable valves and balloon-expandable valves in patients with ascending aortic dilation who undergo transcatheter aortic valve replacement.
- Trial name
- NCT06743568
- Testing
- Transcatheter aortic valve replacement
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Heart Failure, Heart Failure, Diastolic
Personalized Atrial Septostomy for Heart Failure
This study aims to investigate the safety and efficacy of personalized atrial septostomy (PAS) with combined use of radiofrequency-ablation and balloon-dilation (CURB) in heart failure with reduced ejection fraction (HFrEF) and…
- Trial name
- PAS (NCT04573166)
- Testing
- Personalized atrial septostomy with combined use of radiofrequency-ablation and balloon-dilation
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- China National Center for Cardiovascular Diseases
Bicuspid Aortic Valve, Aortic Regurgitation
Investigation of Patients With BAV Requiring Valve and/or Aortic Repair (GISSI Outliers VAR)
Prospective longitudinal study on four small groups of surgical patients affected by: BAV with isolated regurgitation, BAV associated with aorta dilatation, or both and BAV with isolated stenosis in over 60 year-old patients.
- Conditions
- Bicuspid Aortic Valve, Aortic Regurgitation, Aortic Dilatation
- Trial name
- VAR (NCT02283970)
- Where
- 10 sites in Italy
- Volunteers
- 62 people
- Sponsor
- Gruppo di Ricerca GISSI
Dilated Cardiomyopathy with Conduction Defect, Left Bundle-Branch Block
Conduction System Pacing Versus Biventricular Pacing for Cardiac ResYNChronization
Cardiac resynchronization therapy (CRT) with biventricular pacing (BiV) is the cornerstone treatment for heart failure patients with ventricular dyssynchrony.
- Conditions
- Dilated Cardiomyopathy with Conduction Defect, Left Bundle-Branch Block, Heart Failure, Resynchronization Therapy
- Trial name
- CSP-SYNC (NCT05155865)
- Testing
- Resynchronization with conduction system pacing, Cardiac resynchronization therapy with biventricular stimulation
- Where
- Slovenia
- Volunteers
- 62 people
- Sponsor
- University Medical Centre Ljubljana
Pain
Pupillary Dilation Reflex (PDR) Evaluation During General Anesthesia
In this study, the pupillary dilation reflex is measured as a nociceptive indicator during elective abdominal surgery under general anesthesia.
- Trial name
- NCT02942316
- Testing
- Pupil dilation reflex measurement
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- University Hospital, Antwerp
Non-Alcoholic Fatty Liver Disease
The Effect of Coenzyme Q10 on Endothelial, Vascular and Myocardial Function
Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular risk. The aim of this study is to investigate the effects of coenzyme Q10 (CoQ10) on endothelial, vascular and myocardial function in patients…
- Trial name
- NCT05941910
- Testing
- Q10
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Coronary Artery Ectasia
Safety And Efficacy Results of Percutaneous Renal Stent Implantation in Ectatic and Aneurysmatic Coronary Arteries
The aim of this study was to evaluate the efficacy and safety of renal stents implanted in ectatic/aneurysmatic coronary arteries.
- Trial name
- NCT05410678
- Testing
- Renal stent
- Volunteers
- 63 people
- Sponsor
- Bursa Postgraduate Hospital
Acute Coronary Syndrome (ACS)
Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome
The investigators' work proposes to evaluate the effectiveness of the Acid Nicotinique (Niaspan®), only molecule currently marketed, ready to raise the plasmatic levels of HDL-c.
- Trial name
- EVANACS (NCT00855257)
- Testing
- Acid Nicotinique
- Where
- France
- Volunteers
- 93 people
- Sponsor
- French Cardiology Society
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation, Cardiac Thrombus
VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management
The investigators aimed to use pharmacogenetic information in clinical practise which may lead to rapid, efficient, and safe warfarin dosing in this observational prospective study.
- Conditions
- Atrial Fibrillation, Cardiac Thrombus, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT00970892
- Testing
- Warfarin dose titration
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara University
Chronic Ischemic-Hypoxic Enteropathy
Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease
This single-center, double-blind, randomized, intra-individual crossover controlled study aims to investigate the efficacy and safety of intestinal oxygen therapy via a deep intestinal catheter as a targeted route for intestinal…
- Trial name
- NCT07621367
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Heart Failure, Myocardial Infarction
A Multinational Trial To Evaluate The Parachute Implant System
The primary objective is to assess the safety of the CardioKinetix Parachute Implant and Delivery System in the partitioning of the left ventricle in patients with heart failure due to ischemic heart disease.
- Trial name
- PARACHUTE (NCT01286116)
- Testing
- Parachute Implant
- Where
- 13 sites in France, Germany and 6 more
- Volunteers
- 59 people
- Sponsor
- CardioKinetix, Inc
Artery; Dilatation
Safety and Tolerability of Nitro for Radial Artery Dilation
Phase 1, single-center, open-label clinical study to assess the safety and efficacy of topical nitroglycerin on dilation of the radial artery.
- Trial name
- RADial (NCT05239013)
- Testing
- Nitroglycerin ointment
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Leukemia
Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload
The goal of this clinical research study is to learn about the safety and level of effectiveness of aquapheresis compared to diuretic drugs. Diuretic drugs are designed to help the kidneys to form more urine.
- Trial name
- NCT01508260
- Testing
- Aquapheresis, Furosemide
- Sponsor
- M.D. Anderson Cancer Center