Clinical trials: Coronary Patient
Coronary Artery Disease
S-FLEX Netherlands Registry: Prospective Evaluation of the Supraflex Family Sirolimus-eluting Coronary Stent System
The primary objective of this registry is to evaluate the safety and efficacy of the Supraflex Family sirolimus-eluting coronary stent system in a 'real-world' patient population requiring stent implantation.
- Trial name
- NCT03443999
- Testing
- Supraflex Family Sirolimus-eluting Coronary Stent System
- Where
- 7 sites in Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Sahajanand Medical Technologies Limited
Coronary Artery Disease
MDCT of the Coronary Arteries in Heart Transplanted Patients
Heart transplanted patients often develop coronary artery disease and therefore have their coronary arteries examined with coronary angiography once a year.The purpose of the study is to validate computer tomography of the…
- Trial name
- NCT00403299
- Testing
- MDCT of the coronary arteries.
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease
HELIOS China Registry: Evaluation of the HELIOS Stent in a 'Real-World' Patient Population
The study aims to evaluate the safety and efficacy of biodegradable polymer sirolimus-eluting coronary stent system (HELIOS) in patients with coronary artery disease .
- Trial name
- NCT03916432
- Testing
- HELIOS biodegradable polymer sirolimus-eluting stents
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Xijing Hospital
Infective Endocarditis
Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
The recommended length of antibiotic treatment to patients with infective endocarditis is 4-6 weeks. All patients receive the same dosis except for those with renal impairment who receive a smaller dose.
- Trial name
- NCT02033421
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Aortic Stenosis
PERIGON Japan Trial
The purpose of this study is to evaluate the safety and effectiveness of the 17mm MDT-2215 aortic valve bioprosthesis.
- Trial name
- NCT02686814
- Testing
- 17mm MDT-2215 aortic valve bioprosthesis
- Where
- 10 sites in Japan
- Volunteers
- 25 people
- Sponsor
- Medtronic Cardiac Surgery
Stable Angina (SA), NSTE-ACS (NSTEMI and UA)
Utilisation of Angiox® in European Practice
The objective of this study is to determine utilisation patterns in patients receiving Angiox® in participating European centres.
- Conditions
- Stable Angina (SA), NSTE-ACS (NSTEMI and UA), STEMI (STE-ACS)
- Trial name
- EURO-vision (NCT01011504)
- Where
- 2 sites in France, Germany
- Volunteers
- 2,019 people
- Sponsor
- The Medicines Company
Congestive Heart Failure, Electric Muscle Stimulation
Electrical Muscle Stimulation in Congestive Heart Failure
This trial is to evaluate two types of electrical muscle Stimulation (EMS) stimulation (low intensity "conventional stimulation" vs.
- Conditions
- Congestive Heart Failure, Electric Muscle Stimulation, Severe Decondition, Elderly Person
- Trial name
- NCT03793647
- Testing
- Electrical muscle devise
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Kantonsspital Olten
Heart Failure, Reduced Ejection Fraction Heart Failure
Personalized IoT-based Physical Activity Monitoring System for Heart Failure Patients
Current literature emphasizes the importance of increasing physical activity, ensuring its continuity, and reducing sedentary behaviors in patients with heart failure (HF).
- Trial name
- IoT-HFActive (NCT07171372)
- Testing
- Device&behavioral
- Volunteers
- 82 people
- Sponsor
- Abant Izzet Baysal University
Acute Myocardial Infarction
MYSTAR-5-YEAR: Long-term Follow-up of Patients With Ischemic Heart Disease Treated With Cell Therapy
The MYSTAR-5-YEAR study controls the patients 5 years after treatment with combined (intramyocardial and intracoronary) delivery of autologous BM-MNCs.
- Trial name
- MYSTAR-5-YEAR (NCT01395212)
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Acute Ischemic Stroke, Atrial Fibrillation
Early Versus Late Initiation of Anticoagulation in Mild-to-moderate AIS Patients With NVAF
The goal of this clinical trial is to compare the effectiveness between early and late initiation of anticoagulation therapy in acute ischemic stroke (AIS) patients with non-valvular atrial fibrillation (NVAF).
- Trial name
- ASAP (NCT06057467)
- Testing
- Anticoagulation Agents
- Where
- 2 sites in China
- Volunteers
- 2,351 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy)
OCT-based DAPT Cessation in HBR Patients
This study investigates whether patients with diabetes mellitus (DM) and a high risk of bleeding can safely stop dual antiplatelet therapy (DAPT) earlier than usual after receiving a special type of stent called a polymer-free…
- Conditions
- High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy), Coronary Artery Disease, Diabetes Mellitus
- Trial name
- NCT07238764
- Testing
- Optical Coherence Tomography-based early DAPT discontinuation
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Postoperative Delirium
Automated Pupillometry in Patients Underwent Cardiac Surgery to Predict Postoperative Delirium
The rate of postoperative delirium in patients who underwent cardiac surgery is very high. Different predictors and/or scores were studied for the prediction of Post Operative Delirium (POD)after heart surgery, but none of them…
- Trial name
- NCT06255132
- Testing
- Automated pupillometer NPi-200
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Unstable Angina Pectoris
Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study
The purpose of this study is to evaluate the differences in pharmacokinetics and pharmacodynamics of ticagrelor and its active metabolite depending on the strategy of the drug administration in patients with unstable angina…
- Trial name
- NCT02612116
- Testing
- Pulverized ticagrelor sublingually, Pulverized ticagrelor orally, Integral ticagrelor
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Heart Failure
Patient-Reported Outcome Measurement in Heart Failure Clinic
This is a randomized study evaluating the effect of routinely collecting a standardized questionnaire of heart failure health status during heart failure clinic visits.
- Trial name
- PRO-HF (NCT04164004)
- Testing
- Kansas City Cardiomyopathy Questionnaire-12
- Where
- United States
- Volunteers
- 1,249 people
- Sponsor
- Stanford University
Atrial Fibrillation
Assessment of Thrombotic Status in Patients With Atrial Fibrillation
Investigators will assess the impact of treatments for atrial fibrillation on participant's thrombotic status
- Trial name
- NCT02583971
- Volunteers
- 500 people
- Sponsor
- East and North Hertfordshire NHS Trust
Consecutive Incident Adult Patients Undergoing Elective Cardiac Surgery
The Diagnostic Role of Cystein-rich Protein 61 (Cyr61) in Acute Kidney Injury: Correlation With the Harmonic Analysis of Arterial Pressure Pulse Waves.
Acute kidney injury (AKI) is a common heterogeneous disease that complicates several medical and surgical conditions. Recent studies have demonstrated that the occurrence of AKI significantly increase the risk of adverse…
- Trial name
- NCT01876134
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Cardiac Surgery, Coronary Artery Bypass Surgery
Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB
The purpose of this study is to examine the safety and efficacy of Angiomax as an alternative anticoagulant to heparin with protamine reversal in patients undergoing off-pump coronary artery bypass graft surgery.
- Trial name
- OPCAB (NCT00073593)
- Testing
- Bivalirudin, Heparin, Protamine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Medicines Company
Infection, Hypervolemia
Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients
The overall goal of this multicenter project is to characterize the expected normal range of Peripheral IntraVenous Volume Analysis (PIVA) values during a euvolemic state, and how those ranges may be altered by comorbidities; the…
- Conditions
- Infection, Hypervolemia, Hypovolemia, Septic Shock
- Trial name
- PIVA (NCT03736421)
- Testing
- Peripheral Intravenous Analysis (PIVA), Non-invasive fluid response measure, Passive leg raise (PLR)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Arrhythmia
To Validate the Specific Patterns of Magnetocardiography, a Non-invasive Non-contact Examination for Patients With Ischemic Heart Disease or Cardiac Arrhythmia
ECG is one of the most important non-invasive method to diagnose CAD and arrhythmia. However, clinically it still has its limitation.
- Trial name
- NCT00965614
- Testing
- MCG
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Renal Impairment
Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes
Patients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood…
- Trial name
- BIOMARKERS (NCT00948116)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Barts & The London NHS Trust
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