Clinical trials: Coronary Patient
Coronary Artery Disease
T-Wave Alternans (TWA) Reproducibility in CAD Patients
Microvolt T-Wave Alternans (MTWA) is a relatively new non-invasive method for identifying patients at increased risk of sudden death from ventricular arrhythmias.
- Trial name
- NCT00644345
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Cardiogenic Shock
Left Ventricular Unloading to Improve Outcome in Cardiogenic Shock Patients on VA-ECMO
Prospective, multi-center, randomized (1:1), controlled trial of Impella for active left ventricular unloading on top of veno-arterial extracorporeal membrane oxygenation vs.
- Trial name
- NCT05577195
- Testing
- Impella, VA-ECMO
- Where
- Germany
- Volunteers
- 198 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atherosclerosis, Type 2 Diabetes Mellitus
Effect of Sitagliptin on Progression of Coronary Intermediate Lesion
This study was to investigate the Effect of Sitagliptin, a dipeptidyl peptidase-4 inhibitor, on Progression of Coronary Intermediate Lesion.
- Trial name
- NCT02655757
- Testing
- Sitagliptin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Li Bo
Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation
Clinical Application of Low-Field Magnetic Resonance Imaging in Patients on Extracorporeal Cardiopulmonary Resuscitation
Timely identification of acute brain injury (ABI) patterns in patients with extracorporeal cardiopulmonary resuscitation (ECPR) is essential for prognostic assessment and optimization of clinical management, particularly…
- Conditions
- Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation, Acute Brain Injury
- Trial name
- NCT07526701
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Capital Medical University
Coronary Artery Occlusive Disease
Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Off-pump Coronary Artery Bypass Graft
High mobility group 1 (HMGB1) protein is both a nuclear factor and a secreted protein, and has recently been identified as a cytokine mediator of systemic inflammation.
- Trial name
- NCT02206412
- Where
- South Korea
- Volunteers
- 255 people
- Sponsor
- Yonsei University
Non-cardiac Chest Pain, Cardiac Anxiety
Internet-delivered CBT for Patients With NCCP
Non-cardiac chest pain (NCCP) is common and has substantial impact on patients' psychological wellbeing, quality of life and healthcare use.
- Trial name
- IKSIT (NCT03336112)
- Testing
- Internet-delivered cognitive behavioral therapy (I-CBT), Information program
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Linkoeping University
Valvular Heart Disease
The Impact of Sleep-disordered Breathing on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Valvular Heart Surgery
Sleep-disordered breathing has a prevalence of 30~80% in patients with heart diseases. Various studies have revealed a correlation between the incidence and various diseases such as heart failure, hypertension, diabetes, and…
- Trial name
- NCT04080219
- Where
- South Korea
- Volunteers
- 414 people
- Sponsor
- Yonsei University
Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF)
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation require treatment with different antithrombotic drugs.
- Conditions
- Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor
- Trial name
- MATRIX-2 (NCT05955365)
- Testing
- P2Y12 inhibitor, Aspirin, DOAC
- Where
- 15 sites in Belgium, France and 7 more
- Volunteers
- 3,010 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Failure, Atrial Fibrillation
Cardiac Contractility Modulation in Patients With Chronic Heart Failure and the Various Forms of Atrial Fibrillation
Chronic heart failure (CHF) is a global pandemic which affects around 26 million people worldwide and develops in 10% of people over 70 years .
- Conditions
- Heart Failure, Atrial Fibrillation, Left Ventricular Ejection Fraction
- Trial name
- NCT05550792
- Testing
- optimizer smart
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Left Ventricular Systolic Dysfunction
3D & Speckle Tracking Together as a Marker for Early Outcome in Cardiac Surgery
Patients presenting with Left Ventricle (LV) dysfunction undergoing cardiac surgery are at increased risk of perioperative morbidity and mortality.
- Trial name
- NCT02642770
- Testing
- Transesophageal echocardiography
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cardiac Valve Replacement Complication
Short Term Effect of Vitamin D Supplementation on the Clinical Outcomes in Patients Undergoing Valve Replacement Surgery
This study evaluates the effect of Vitamin D supplementation on ICU and hospital LOS in patients undergoing valve replacement surgery.
- Trial name
- NCT04085770
- Testing
- Alfacalcidol 1 MCG Oral Capsule
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Ventricular Arrythmias
Home-Monitoring in Implantable Cardioverter Defibrillator (ICD) Patients
The purpose of this study is to investigate the cost-effectiveness and effectiveness of remote-monitoring compared to standard care in patients with implantable cardioverter defibrillator.
- Trial name
- Monitor-ICD (NCT00787683)
- Testing
- Home-monitoring provided by LUMAX ICD device and CardioMessenger II
- Where
- 13 sites in Germany
- Volunteers
- 416 people
- Sponsor
- F. Mueller-Riemenschneider
Heart Failure With Reduced Ejection Fraction, Thoracic Epidural Anesthesia
Thoracic Epidural Anesthesia Reduces Mortality and Rehospitalization for Patients With Heart Failure With Reduced Ejection Fraction
Despite significant scientific breakthrough in management, patients with heart failure with reduced ejection fraction (HFrEF) remain high morbidity and mortality, with a 5-year survival rate of 25% after hospitalization for…
- Trial name
- NCT06068166
- Testing
- TEA plus GDMT, GDMT
- Volunteers
- 1,840 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Elective Percutaneous Coronary Intervention, Ischemic Reperfusion Injury
Cardio-protective Effect of Metformin in Patients Undergoing PCI
This is a two-arm randomized parallel study. Patients who will be meeting the above-mentioned criteria and agree to take part in the study, were asked to sign an informed consent prior conducting the study.
- Trial name
- NCT05708053
- Testing
- Metformin
- Where
- 3 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Atrial Fibrillation
Safety and Effectiveness of Low Dose Edoxaban in Patients With NVAF
The efficacy and safety of edoxaban has not been adequately studied in Asians versus non-Asians, who are quite different physiologically from each other.
- Trial name
- LEDIOS (NCT03554837)
- Where
- South Korea
- Volunteers
- 2,562 people
- Sponsor
- Samsung Medical Center
Pain, Acute, Congenital Heart Disease
Transverse Thoracic Plane Block in the Pediatric Cardiac Patient
Postoperative pain after cardiothoracic surgery can be a significant problem interfering with recovery, yet difficult to manage due to the sedating effects of opiates.
- Trial name
- TTPPCT (NCT04138745)
- Testing
- Transverse Thoracic Plane Block
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Coronary Artery Disease
Effectiveness of Clopidogrel Resinate in PCI(PRIDE)
This study is an open label, multi-center, randomized trial, which is designed to evaluate the efficacy and safety of clopidogrel derivative (Pregrel®) therapy for 12 months in patients undergoing PCI compared to conventional…
- Trial name
- NCT01349777
- Testing
- Pregrel®, Plavix®
- Where
- 3 sites in South Korea
- Volunteers
- 1,056 people
- Sponsor
- Seung-Jung Park
Cardiac Arrest, Frailty
The Impact of Frailty on Cardiopulmonary Resuscitation Adverse Outcomes in Patients Requiring Code Blue Activation
The aim of this study was to determine the independent association of frailty with cardiopulmonary resuscitation and predictive factors in patients triggering code blue response
- Conditions
- Cardiac Arrest, Frailty, Respiratory Arrest
- Trial name
- NCT06405581
- Testing
- Edmonton frailty scale calculation
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Umraniye Education and Research Hospital
Heart Failure With Preserved Ejection Fraction
The Impact of Exercise Training on Functional Capacity in Heart Failure
The purpose of this study is to determine whether exercise training will improve functional capacity in patients with heart failure and preserved ejection fraction.
- Trial name
- NCT01288365
- Testing
- Exercise training
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Acute Myocardial Infarction
Cell Therapy in Myocardial Infarction
The purpose of this study is to determine cell therapy efficacy in patients with ST elevation acute myocardial infarction (STEMI)
- Trial name
- EMRTCC (NCT00350766)
- Testing
- Autologous Bone Marrow Mononuclear Cells (ABMMC) Transplantation
- Where
- Brazil
- Volunteers
- 166 people
- Sponsor
- Ministry of Health, Brazil
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