Clinical trials: Coronary Patient
Chest Pain
A Comparison of the TIMI, GRACE, HEART and HEARTSIL Scores
Chest pain is one of the most common reasons for emergency admission. Chest pain can be caused by many cardiac and noncardiac causes. Acute Coronary Syndrome (ACS) is one of the most im-portant of these etiologies.
- Trial name
- NCT04661722
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Konya Meram State Hospital
Acute Myocardial Infarction
Disparities in the Proportion of Ticagrelor and Prasugrel-eligible Patients with Acute Coronary Syndrome in a Real-world Registry
The primary objective of this study is to compare patients eligible for ASS and Ticagrelor against those eligible for ASS and Prasugrel.
- Trial name
- AZ-DAPT (NCT05774431)
- Testing
- There was no intervention necessary.
- Where
- Germany
- Volunteers
- 6,789 people
- Sponsor
- University Hospital Heidelberg
STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure
Reliability of 3D angio QFR functional evaluation of all non culprit lesions >50% in STEMI patients during first acute procedure
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease
- Trial name
- NCT02998853
- Testing
- QFR measurement by dedicated workstation on xrays angio selected runs
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Sant'Anna e San Sebastiano
Myocardial Infarction
Cardiovascular Medication Use Before First Myocardial Infarction
Large randomised trials have shown that cardiovascular medications prescribed to patients at high cardiovascular risk are effective in reducing the incidence of cardiovascular events.
- Trial name
- NCT01692795
- Where
- United Kingdom
- Volunteers
- 17,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Cardiovascular Surgery, Pain, Postoperative
Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery
The purpose of this study is to find out what effects (good and bad) that the study medicine called "liposomal bupivacaine" has on subjects that are undergoing a sternotomy.
- Conditions
- Cardiovascular Surgery, Pain, Postoperative, Block
- Trial name
- NCT04333095
- Testing
- Liposomal bupivacaine, Normal Saline Flush, 0.9% Injectable Solution_#1
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor Research Institute
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
CABG, Coronary Artery Disease
Study of the Use of a Single Dose of Erythropoietin to Treat Acute Myocardial Ischemia
This is a phase 2 study that evaluates the effect of intravenous administration of a bolus EPO on the activation of EPOR-signal transduction cascades and myocardial apoptosis during cardiopulmonary bypass surgery.
- Trial name
- DREAM (NCT00524901)
- Testing
- Epoetin alpha, NaCl 0.9%
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Coronary Artery Disease, Adherence
Using Feedback Reports to Improve Medication Adherence
The purpose of this research study is to improve statin medication adherence among Veterans with coronary artery disease with poor adherence to medications.
- Trial name
- NCT02480530
- Testing
- Individual Feedback, Feedback Friend
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
SGLT2 Inhibitiors Remodeling Effect, Chronic Heart Disease
Effect of Sodium Glucose Cotransporter 2 Inhibitiors on Left Ventricular Remodeling Among Diabetic and Non Diabetic Patients With Chronic Heart Failure
To evaluate the efficacy of SGLT2 inhibitors on left ventricular global longitudinal strain and diastology parameters among diabetic and non-diabetic patients with chronic heart failure
- Trial name
- NCT06137430
- Testing
- Sodium-glucose cotransporter 2 inhibitor
- Volunteers
- 98 people
- Sponsor
- Assiut University
Chronic Heart Failure
Nurse-Led Education for Heart Failure Self-Care and Stability
Heart failure is a chronic condition that can lead to frequent hospitalizations and reduced quality of life. This study aims to evaluate whether a nurse-led, face-to-face educational intervention can improve clinical stability…
- Trial name
- EDUCATE (NCT07280728)
- Testing
- Nurse-Led Face-to-Face Educational Intervention (Teach-Back Method)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Acute Kidney Injury
Effects of Oral Protein Load on Kidney Function in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) occurs in approximately one-third of patients undergoing cardiac surgery (CS), and represents one of the most significant negative predictors of patient outcome in this population.
- Trial name
- NCT03102541
- Testing
- None intervention
- Volunteers
- 214 people
- Sponsor
- University of Giessen
Cardiac Surgery, Cardioplegia
Evaluation of Clinical Impact of the Type of Cardioplegia Used in the Patient Undergoing Major Cardiac Surgery.
Phase IV clinical trial of a single-blind, prospective and longitudinal randomized intervention comparing patients undergoing major cardiac surgery with extracorporeal circulation who are administered Custodiol crystalloid…
- Conditions
- Cardiac Surgery, Cardioplegia, Heart Arrest
- Trial name
- NCT06530641
- Testing
- Custodiol Htk Soln, Buckberg Cardi-Braun
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Lourdes Montero Cruces
Heart Arrest
Hydrocortisone in Patients of Out-of-hospital Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) is an important issue for the emergency physicians and co-workers. How to improve the return of spontaneous circulation (ROSC) rate and prognosis of these patients challenges the emergency…
- Trial name
- NCT00172354
- Testing
- Hydrocortisone
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Congestive Heart Failure
To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction
This study injects a person's own stem cells into heart muscle tissue after a person has one or more heart attacks. The purpose of the study is whether the stem cells will improve a patient's heart performance.
- Trial name
- MARVEL (NCT00526253)
- Testing
- MyoCell, Hypothermosol
- Where
- 33 sites in United States
- Volunteers
- 170 people
- Sponsor
- Bioheart, Inc.
Congestive Heart Failure, Renal Dysfunction
Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
The purpose of the study is to show that low dose recombinant BNP coupled with phosphodiesterase V inhibition will improve renal dysfunction and promote relief of volume overload in patinets with acute decompensated heart failure…
- Trial name
- BNP+PDEVI (NCT00818701)
- Testing
- low dose Nesiritide, nesiritide, Sildenafil
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Heart Failure, Chronic Kidney Disease
Dapagliflozin Post Marketing Surveillance in HF and CKD
This is an observational, non-interventional, single-arm multicenter study. The objectives of this study are to assess safety and effectiveness of Forxiga in a real world setting in patients who are prescribed with the study drug…
- Trial name
- NCT05134701
- Where
- 26 sites in South Korea
- Volunteers
- 815 people
- Sponsor
- AstraZeneca
Shock, Cardiogenic
Abciximab in Patients Undergoing Percutaneous Coronary Intervention for Cardiogenic Shock
Outcome of patients with myocardial infarction complicated with cardiogenic shock is very poor. Although early mechanical revascularization has been demonstrated superior to conservative medical treatment, mortality range remains…
- Trial name
- NCT00420030
- Testing
- Abciximab
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Medication Adherence
A Mobile Phone Based Medication Reminder Program
This study evaluates the feasibility and acceptability of using mobile applications to improve medication adherence. Participants in the experimental group will receive educational materials and daily reminders through mobile…
- Trial name
- NCT02793830
- Testing
- Daily reminders of taking medications, Educational materials
- Volunteers
- 49 people
- Sponsor
- Duke University
Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
The Effect of Losartan in Bicuspid Aortic Valve Patients
The specific aims of this study are to: Establish baseline levels of circulating MMP-2 and -9 , TIMP-1and- 2 and TGFB levels in individuals with bicuspid aortic valve and ascending aortic or aortic sinus measurements >40mm.
- Trial name
- NCT01390181
- Testing
- Cozaar
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Atrial Fibrillation, Cardiac Rehabilitation
The Application of Internet+ Home-based Cardiac Rehabilitation in Atrial Fibrillation Patients After RFCA
Epidemiological reports show that the incidence of atrial fibrillation continues to increase. AF is the most common arrhythmia with high mortality and disability rate.
- Trial name
- NCT04414007
- Testing
- Internet+ home-based cardiac rehabilitation, Conventional rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing Medical University
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