Clinical trials: Coronary Patient
Chronic Stable Heart Failure
Qishenyiqi for Ventricular Remodeling After Myocardial Infarction
The effects of Qishenyiqi dripping pill on cardiac remodeling in patients with chronic stable heart failure have not been reported.
- Trial name
- NCT06699407
- Testing
- Qishenyiqi dripping pills
- Where
- 3 sites in China
- Volunteers
- 210 people
- Sponsor
- Qilu Hospital of Shandong University
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation.
Atrial The treatment of atrial fibrillation (AF) includes 2 axes: the prevention of the cardio-embolic risk and rhythm control. The possibilities for this control are antiarrhythmic drugs and, above all, catheter ablation, an…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Catheter Ablation, Atrial Cardiomyopathy
- Trial name
- CATS-AF (NCT05565183)
- Testing
- MRI (with injection of contrast product)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
eHealth, Coronary Artery Disease
Effectiveness of eHealth on the Self-management of Health Status and QOL Among CAD Patients
This article uses the smart medical case management tracking system, combined with various terminal devices to fully record the measured data (pulse, blood pressure) for case home care tracking to prevent the occurrence and…
- Conditions
- eHealth, Coronary Artery Disease, Quality of Life, Self-management
- Trial name
- NCT04146766
- Testing
- eHealth
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Defense Medical Center, Taiwan
Coronary Artery Disease
Different Regimen of Aprotinine(Trasylol) Administration in Patients Receiving Antiplatelet Therapy With Clopidogrel (Plavix)
Clopidogrel (Plavix), a platelet ADP receptor antagonist, has become the standard of care to prevent thrombosis in interventional cardiology and is increasingly being used in unstable angina and NSTEMI.
- Trial name
- NCT00257751
- Testing
- Aprotinine
- Volunteers
- 400 people
- Sponsor
- Oslo University Hospital
Chronic Kidney Disease (CKD), Coronary Artery Disease (CAD)
Coronary Artery Disease Screening in Patients With Chronic Kidney Disease
Patients with chronic kidney disease (CKD) have a markedly increased cardiovascular risk, with coronary artery disease being a leading cause of morbidity and mortality.
- Trial name
- EVACKD (NCT07585695)
- Where
- France
- Volunteers
- 283 people
- Sponsor
- University Hospital, Grenoble
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Acute Decompensated Heart Failure; Renal Dysfunction
Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart Failure
The purpose of this study is to determine the efficacy and safety of IV SLV320 in acute heart failure patients with renal dysfunction.
- Trial name
- NCT00744341
- Testing
- SLV320
- Where
- 105 sites in United States, Canada and 9 more
- Volunteers
- 46 people
- Sponsor
- Solvay Pharmaceuticals
Atrial Fibrillation
Short Term Warfarin Therapy for Radiofrequency Catheter Ablation of Atrial Fibrillation
We hypothesized that in patients with low CHADS-VASc score (2 or < 2), there is no difference in thromboembolic or bleeding events between patients with short term warfarin therapy (2 weeks after catheter ablation) and…
- Trial name
- NCT01991951
- Testing
- warfarin
- Where
- South Korea
- Volunteers
- 520 people
- Sponsor
- Korea University Anam Hospital
Coarctation of the Aorta
Statins and Endothelial Function in Patients With Coarctation of the Aorta
Coarctation of the aorta (CoA) accounts for approximately 8% of all congenital heart problems. Patients with CoA are well known to have an increased rates of early heart disease, high blood pressure, heart failure and stroke.
- Trial name
- NCT00767572
- Testing
- atorvastatin, Sugar pill
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Non-valvular Atrial Fibrillation
WAVECREST Post Market Clinical Follow-Up (PMCF) Study
The WAVECREST PMCF Study is a prospective, non-randomized, multicenter study to confirm safety and performance of the Coherex WaveCrest Left Atrial Appendage (LAA) Occlusion System in the current medical practice setting in…
- Trial name
- NCT03204695
- Testing
- Percutaneous LAA Closure, Anticoagulation or Clopidogrel
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- Coherex Medical
Heart Failure
Medico-economic Evaluation of Therapeutic Adaptation Guided by the Soluble Suppression of Tumorigenicity 2 (sST-2) Biomarker in the Management of Patients With Acute Heart Failure
Management of patients with heart Failure remains a major health concern because of the high rate of rehospitalization, mortality and induced-cost.
- Trial name
- ICAME (NCT04554277)
- Testing
- Biomarker guided therapy
- Where
- 12 sites in France
- Volunteers
- 154 people
- Sponsor
- University Hospital, Montpellier
Postoperative Pain
Efficacy of Erector Spinae Plane Block in Caridac Surgery
Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT05312957
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pulmonary Hypertension, Left Heart Disease
A Multiple Dose Titration Study of MK-8892 in Participants With Pulmonary Hypertension and Left Heart Disease (MK-8892-007)
This study will assess multiple doses of MK-8892 administered to participants with pulmonary hypertension "out of proportion" (PHOOP) and heart failure with reduced left ventricular ejection fraction (rEF).
- Trial name
- NCT02078557
- Testing
- MK-8892
- Volunteers
- 4 people
- Sponsor
- Merck Sharp & Dohme LLC
Insufficiency;Cardiac, Cancer
Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment
New therapies for cancer increased patient survival, but led to the recognition of adverse effects associated with cancer treatment, such as the use of chemotherapy.
- Conditions
- Insufficiency;Cardiac, Cancer, Cardiotoxicity, Heart Failure
- Trial name
- NCT04047901
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Pain, Post Operative
Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients
The study will be designed to compare the analgesic effect of ultrasound-guided pectointercostal fascial plane block versus tansversus thoracic plane block in adult cardiac surgery.
- Trial name
- NCT05323305
- Testing
- ultrasound guided regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Acute Coronary Syndrome
Effect of Free Ticagrelor Fraction on Platelet Membrane Post MI
The purpose of this study is to assess: the population pharmacokinetics of unbound ticagrelor and its metabolite in acute coronary syndrome patients treated by ticagrelor ticagrelor and its metabolite levels by LC-MS/MS
- Trial name
- PLATIME (NCT03658005)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Right Bundle-Branch Block
Adaptive Cardiac Resynchronization Therapy in Patients With RBBB
This study will address whether acute adaptive RV pacing in sinus rhythm patients with severe LV systolic dysfunction and RBBB is superior to no ventricular pacing, and is as effective as echocardiographically optimized…
- Trial name
- NCT05936294
- Testing
- Optimization of CRT Device
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Henry Ford Health System
COVID-19, Myocardial Reperfusion Injury
Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19
The study will analyze the incidence, clinical outcomes and predictors of myocardial injury in a large patient population with COVID-19 treated in Mount Sinai Hospital (MSH) system.
- Conditions
- COVID-19, Myocardial Reperfusion Injury, Cardiovascular Diseases
- Trial name
- NCT04397939
- Where
- United States
- Volunteers
- 4,695 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Kidney Disease, Heart Rate Variability
Heart Rate Variability in Chronic Kidney Disease Patients
Use 24hr Holter ECG, ultrasound and cardiac fibrosis markers in the chronic kidney disease patients
- Trial name
- NCT00824577
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation, Recurrence
Stepwise Approach Versus Linear Ablation in Patients With Recurrence of Persistent Atrial Fibrillation
Catheter ablation of persistent atrial fibrillation (AF) remains a challenging procedure. Even in experienced centres, repeat interventions are necessary in up to 70 of patients to achieve sinus rhythm at a long-term follow-up.
- Trial name
- REDO-AF (NCT01229475)
- Testing
- Ablation with stepwise approach, Linear ablation
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Deutsches Herzzentrum Muenchen
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