Clinical trials: Coronary Patient
Diabetes Mellitus, Coronary Disease
Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease
This trial evaluates the effects of Empagliflozin versus Sitagliptin, in addition to standard of care, on global myocardial perfusion reserve using dynamic single-photon emission computed tomography (SPECT) images.
- Trial name
- ELITE (NCT03208465)
- Testing
- Empagliflozin, Sitagliptin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- CHEOL WHAN LEE, M.D., Ph.D
Chronic Obstructive Pulmonary Disease
Effects of Breathing Retraining in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Conventional pulmonary rehabilitation programs improve exercise tolerance, peripheral muscle strength, and health related quality of live but not pulmonary function in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01175265
- Testing
- respiratory biofeedback
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital, Essen
Coronary Artery Disease
Traditional Tibetan Medicine for Patients With Coronary Artery Disease
Coronary artery disease has a high death toll in the Western world. Changes in lifestyle, particularly in nutrition and physical activity may significantly reduce a severe coronary atherosclerosis within one year without the use…
- Trial name
- TTM in CAD (NCT00810992)
- Testing
- Nutritional and behavioral program A, Nutritional and behavioral program B
- Where
- Germany
- Volunteers
- 524 people
- Sponsor
- University Hospital Tuebingen
Hemorrhage, Soft Tissue Bleeding
The EVARREST® Paediatric Mild/Moderate Liver and Soft Tissue Bleeding Study
The objective of this study is to evaluate the safety and effectiveness of EVARREST™ Sealant Matrix (EVARREST™ Fibrin Sealant Patch) (EVARREST™) in controlling mild or moderate soft tissue \& parenchymal bleeding during open…
- Conditions
- Hemorrhage, Soft Tissue Bleeding, Hepatic Parenchyma Bleeding
- Trial name
- NCT02227992
- Testing
- EVARREST™ Sealant Matrix, SURGICEL®
- Where
- 10 sites in Belgium, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.
Cardiac Diseases Requiring Surgery
Investigating the Related Factors and Outcome of Kinesiophobia and the Effects of Multidimensional Interventions in Cardiac Surgery Patients
The primary objective of this two-year research project is to investigate the status of activity fear, its related factors, and prognosis in cardiac surgery patients in the first year.
- Trial name
- NCT06625892
- Testing
- the multidimensional interventions
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- Ai-Ling Chang
Hypertrophic Cardiomyopathy
Study of Myocardial Deformation Parameters in Patients With Hypertrophic Cardiomyopathy
The purpose of the study is to investigate the potential correlations of global longitudinal strain and peak left atrial strain, measured by speckle tracking echocardiography with the severity of hypertrophic cardiomyopathy and…
- Trial name
- NCT04112511
- Where
- Greece
- Volunteers
- 250 people
- Sponsor
- AHEPA University Hospital
Acute Coronary Syndromes, Heart Failure
Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting
Suspected acute or subacute cardiovascular diseases-including chest pain, dyspnea, and palpitations-are among the most common reasons for unscheduled emergency department visits and pre-hospital referrals.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Embolism, Deep Vein Thrombosis, HTN-Hypertension
- Trial name
- CESAR (NCT07675434)
- Volunteers
- 25,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Valve Regurgitation, Mitral Valve Regurgitation
Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse…
- Conditions
- Aortic Valve Regurgitation, Mitral Valve Regurgitation, Left Ventricle Dilated, Left Atrium Dilated
- Trial name
- ORMIX (NCT06805253)
- Testing
- Not applicable - observational study
- Where
- 2 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Atrial Fibrillation
The Use of Flecainide for Treatment of Atrial Fibrillation
This prospective observational study will include patients with atrial fibrillation that has indication for treatement with flecainide. Included patients are followed during a 12 month period.
- Trial name
- NCT05084495
- Testing
- Global peak atrial longitudinal strain and ECG
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University
Cardiac Arrest
Pediatric Intubation During CPR
We hypothesized that the video-laryngoscopes are beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of two video-laryngoscopes (the Coopdech video Laryngoscope…
- Trial name
- ETICPR (NCT02289677)
- Testing
- ATMOS Scope, COOPDECH, AirTraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Thyroid Disorders With Acute Coronary Syndrome
Investigate Relationship Between Thyroid Disorders and Acute Coronary Syndrome.
Study Of Thyroid Disorders In Patients With Acute Coronary Syndrome At Sohag University Hospitals.
- Trial name
- NCT07082712
- Testing
- Thyroid profile
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Sohag University
Dexmedetomidine, General Anesthesia
Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period
Perioperative stress may increase the incidence of adverse events in the cardiovascular system and lead to poor prognosis. Dexmedetomidine is a highly selective α2 adrenergic receptor agonist, which can inhibit stress response…
- Conditions
- Dexmedetomidine, General Anesthesia, Cardiac Electrophysiology, Cardiac Function
- Trial name
- NCT04577430
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Coronary Artery Disease, Stable Angina
MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease
The purpose of this study is to determine if MR Perfusion Imaging is non-inferior to coronary angiography with measurement of Fractional Flow Reserve (FFR) in guiding management of patients with stable chest pain.
- Conditions
- Coronary Artery Disease, Stable Angina, Myocardial Ischaemia
- Trial name
- NCT01236807
- Testing
- MR perfusion guidance, FFR guidance
- Where
- United Kingdom
- Volunteers
- 915 people
- Sponsor
- King's College London
Heart Failure
A Crossover Study of Patients With HF to Compare Natriuretic Effects of IR Torsemide vs. ER Torsemide Over 12 Hrs
This is a randomized double-blind crossover study of the patients with stable heart failure, who are taking a loop diuretic. During the study period, the participants' loop diuretics will be replaced by the equivalent dose of…
- Trial name
- EXTOR-HF (NCT06708611)
- Testing
- torsemide
- Where
- United States
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Tricuspid Valve Regurgitation, Tricuspid Valve Disease
VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
Pivotal trial to evaluate the safety and clinical efficacy of the VDyne System for the treatment of symptomatic severe or greater tricuspid regurgitation.
- Conditions
- Tricuspid Valve Regurgitation, Tricuspid Valve Disease, Cardiovascular Diseases (CVD), Heart Valve Diseases
- Trial name
- TRIVITA (NCT07516444)
- Testing
- Transcatheter Tricuspid Valve Replacement (TTVR) with VDyne System, Transcatheter Tricuspid Valve Replacement (TTVR) with Edwards EVOQUE System
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- VDyne, Inc.
Acute Myocardial Infarction (AMI)
Effectiveness of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor Initiation Before Percutaneous Coronary Intervention on Acute Myocardial Infarction Patients
The goal of this clinical trial is to learn if drug tafolecimab works to treat participants with acute myocardial infarction (AMI) scheduled for primary percutaneous coronary intervention (PCI).
- Trial name
- IMPROVE-AMI (NCT06683131)
- Testing
- Tafolecimab
- Where
- 13 sites in China
- Volunteers
- 1,160 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Heart Failure
Safety and Efficacy Study of Istaroxime in Acute Decompensated Heart Failure Patients
The purpose of this study is to assess the safety and efficacy of istaroxime in patients hospitalized for Acute Decompensated Heart Failure (ADHF) not requiring inotropic therapy.This will be done by comparing the hemodynamic…
- Trial name
- NCT00838253
- Testing
- Istaroxime
- Sponsor
- Debiopharm International SA
Heart Failure
Effect of Physical Training Combined Cardiac Resynchronization Therapy in Heart Failure Patients
The investigators hypothesis that exercise training would potentiate the effects of cardiac resynchronization therapy in heart failure patients.
- Trial name
- NCT01939795
- Testing
- exercise training and/or CRT
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
End Stage Heart Disease
Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation
The aim of the study is to assess whether, in patients who are listed for cardiac transplantation in transplantable (T) status, early implantation of a left ventricular assist device is superior to the current therapeutic…
- Trial name
- NCT02387112
- Testing
- Early VAD implantation
- Where
- 18 sites in Germany
- Volunteers
- 102 people
- Sponsor
- German Heart Institute
Coronary Artery Disease, Myocardial Infarction
WENBIT - Western Norway B Vitamin Intervention Trial
PURPOSE OF STUDY Observational studies have demonstrated that elevated levels of plasma total homocysteine is a risk factor for cardiovascular disease.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke
- Trial name
- WENBIT (NCT00354081)
- Testing
- folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine), folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine)
- Where
- 2 sites in Norway
- Volunteers
- 3,096 people
- Sponsor
- Haukeland University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.