Clinical trials: Coronary Stent Occlusion
Coronary Artery Disease
DEBSCAN-IVL. Drug Eluting Balloon or Drug Eluting Stent to Treat CAlcified Nodules After IntraVascular Lithotripsy.
International, investigator-driven, multicenter, open-label, prospective randomized controlled trial where patients with de novo lesions due to calcified nodules (CN) were randomized to drug eluting balloon (DEB) or drug eluting…
- Trial name
- DEBSCAN-IVL (NCT06657833)
- Testing
- Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting balloon, Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting stent
- Where
- 15 sites in Netherlands, Spain
- Volunteers
- 128 people
- Sponsor
- Fundación EPIC
Coronary Artery Disease
A Study of the TAXUS Liberté Stent for the Treatment of de Novo Coronary Artery Lesions in Small Vessels
TAXUS ATLAS Small Vessel is a global, multi-center, single-arm, trial of patients with coronary arteries less than 2.5 mm in diameter who are treated with the TAXUS Liberté stent versus an historical TAXUS Express control derived…
- Trial name
- NCT00371748
- Testing
- TAXUS Liberté-SR, TAXUS™ Express2, Express2
- Where
- 25 sites in United States, New Zealand and 1 more
- Volunteers
- 261 people
- Sponsor
- Boston Scientific Corporation
Arterial Occlusive Diseases, Cardiovascular Diseases
IRIS-BVS AMI Registry
The purpose of this study is to evaluate the relative effectiveness and safety of Bioresorbable Vascular Scaffold in acute myocardial infarction compared to other (drug eluting stents) DES.
- Conditions
- Arterial Occlusive Diseases, Cardiovascular Diseases, Coronary Artery Disease
- Trial name
- IRIS BVS AMI (NCT02699671)
- Testing
- Bioresorbable Vascular Scaffold
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Duk-Woo Park, MD
Coronary Artery Disease
Treatment of Coronary Artery Disease (CAD) With Bare Metal Stent (BMS) Followed by Paclitaxel-Coated Balloon Catheter Versus Paclitaxel-Eluting Stent
The purpose of this study is to compare the one-time application of Paclitaxel from SeQuent Please (Paclitaxel-coated Balloon Catheter) after using the Coroflex Blue (Cobalt Chromium Stent) with the slow releasing of small dose…
- Trial name
- NCT01166711
- Testing
- Coroflex Blue (BMS) followed by SeQuent Please (DEB), Coroflex Please (DES)
- Where
- Poland
- Volunteers
- 202 people
- Sponsor
- Aesculap AG
Coronary Artery Disease
Optical Coherence Tomography for Drug Eluting Stent Safety
Increasing lesion complexity in percutaneous coronary interventions (PCI) has warranted the use of overlapping drug-eluting stents.
- Trial name
- ODESSA (NCT00693030)
- Testing
- sirolimus drug eluting coronary stent Cypher™ (Cordis Corp, Johnson & Johnson Co), paclitaxel polymer drug eluting stent Taxus Libertè™ (Boston Scientific, Natick MS), zotarolimus drug eluting coronary stent Endeavor™ (Medtronic, Santa Rosa, CA)
- Where
- Italy
- Volunteers
- 77 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Coronary Artery Diseases
BIOFLOW III Satellite-Italy Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). 500 subjects will be enrolled in this registry.
- Trial name
- NCT02028728
- Where
- 18 sites in Italy
- Volunteers
- 609 people
- Sponsor
- Biotronik Italia S.p.A.
Acute Coronary Syndrome, Stable Chronic Angina
Angiographic Control Vs. Ischemia-driven Management of Patients Treated with PCI on Left Main with Drug-eluting Stents
The present study aims to compare a planned angiographic control (PAC) follow-up strategy vs. conservative management for patients treated with drug-eluting stents on unprotected left main artery in a prospective, randomized…
- Conditions
- Acute Coronary Syndrome, Stable Chronic Angina, Coronary Artery Disease, Left Main Coronary Artery Disease
- Trial name
- PULSE (NCT04144881)
- Testing
- coronary computed tomography
- Where
- 3 sites in Italy
- Volunteers
- 606 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Coronary Artery Disease, Optical Coherence Tomography
Efficacy and Safety of Zotarolimus-eluting Stent Overexpansion With OCT
Investigators aimed to evaluate efficacy and safety of expansion capacity of zotarolimus-eluting Stent assessed by optical coherence tomography (OCT) in vivo study.
- Conditions
- Coronary Artery Disease, Optical Coherence Tomography, Stent
- Trial name
- ONYSOVER (NCT05340361)
- Testing
- Optical coherence tomography-guided percutaneous coronary intervention, Optical coherence tomography-guided Onyx family stent expansion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Type 2 Diabetes, Coronary Heart Disease
Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics
The TUXEDO-India is a prospective, single blind, multi-center randomized clinical trial to assess the TAXUS Element™ in a consecutive population of diabetic patients with coronary artery disease undergoing coronary…
- Trial name
- Tuxedo (NCT03125772)
- Testing
- TAXUS Element™ Paclitaxel-Eluting Stent System, Xience PRIME Everolimus-Eluting Stent System
- Where
- India
- Volunteers
- 1,830 people
- Sponsor
- Fortis Escorts Heart Institute
Coronary Artery Disease, Multivessel Coronary Artery Disease
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative…
- Trial name
- ROBOT RCT (NCT06378775)
- Testing
- Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention
- Volunteers
- 80 people
- Sponsor
- Cardiology Research UBC
Coronary Artery Disease, Coronary Artery Stenosis
To Evaluate the Performance and Safety of RisoR Crest Everolimus Eluting Coronary Stent System
The study will evaluate the performance and safety of RisoR Crest Everolimus Eluting Coronary Stent System. A total of 2000 participants will be included in the study from India and Italy.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Percutaneous Coronary Intervention, de Novo Lesions in Native Coronary Arteries
- Trial name
- PACIFIER (NCT07098195)
- Testing
- Coronary Stent
- Volunteers
- 2,000 people
- Sponsor
- Poly Medicure Limited
Coronary Artery Disease
Tailored Anti-platelet Therapy After DES Implantation in High-risk Patients
Clopidogrel monotherapy has been found effective in reducing ischaemic cardiovascular and haemorrhagic complications in patients with drug-eluting stent (DES) placement.
- Trial name
- NCT05936606
- Testing
- Clopidogrel monotherapy, Tailored anti-platelet therapy
- Where
- South Korea
- Volunteers
- 3,434 people
- Sponsor
- Yonsei University
Cardiovascular Diseases, Coronary Artery Disease
ABSORB: Postmarketing Surveillance Registry to Monitor the Everolimus-eluting Bioresorbable Vascular Scaffold in Patients With Coronary Artery Disease
The registry aims to evaluate the safety, performance and efficacy of the Everolimus-eluting bioresorbable vascular scaffold (BVS) system in patients with de novo native coronary artery lesions in all-day clinical practice.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Myocardial Ischemia, Coronary Disease
- Trial name
- ASSURE (NCT01583608)
- Where
- 6 sites in Germany
- Volunteers
- 183 people
- Sponsor
- Medical Care Center Prof. Mathey, Prof. Schofer, Ltd.
Coronary Artery Disease (CAD)
Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
To determine the efficacy of prasugrel versus clopidogrel for the reduction of adverse cardiovascular outcomes in patients with high platelet reactivity on clopidogrel after successful implantation of coronary drug-eluting…
- Trial name
- TRIGGER-PCI (NCT00910299)
- Testing
- Prasugrel, Clopidogrel
- Where
- 27 sites in United States, Germany
- Volunteers
- 423 people
- Sponsor
- Eli Lilly and Company
Coronary Artery Bypass, Atherosclerosis
Study of the Xience V Everolimus-eluting Stent in Saphenous Vein Graft Lesions
The specific aim of the SOS-Xience V study is to examine the 12-month incidence of binary angiographic in-stent restenosis after implantation of the Xience V stent in aortocoronary saphenous vein bypass graft lesions.
- Trial name
- SOS-Xience V (NCT00911976)
- Testing
- Xience V coronary stent
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Coronary Artery Disease
Drug Elution and Distal Protection During Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction
The purpose of this study is to evaluate the clinical, echocardiographic and angiographic outcome of distal protection in the infarct related coronary artery and implantation of drug eluting versus bare metal stents in patients…
- Trial name
- NCT00192868
- Testing
- Distal protection and drug eluting stent
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease Aggravated, Myocardial Ischemia
Biofreedom Prospective Multicenter Observational Registry
LEADERS-FREE trial demonstrated the safety and efficacy of polymer-free drug-coated stent (Biofreedom, Biosensors International Technologies, Singapore) in patients with high bleeding risk.
- Conditions
- Coronary Artery Disease Aggravated, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT03045848
- Testing
- Biofreedom drug-coated stent
- Where
- 16 sites in South Korea
- Volunteers
- 194 people
- Sponsor
- Wonju Severance Christian Hospital
Coronary Arteriosclerosis, Angina Unstable
Stents, Drug Eluting Stents, and CABG- Financial and Clinical Impact.
Options for coronary revascularization include stent implantation and coronary bypass surgery. Both modalities have their unique advantages and disadvantages in terms of clinical outcomes as well as financial impact on the…
- Conditions
- Coronary Arteriosclerosis, Angina Unstable, Myocardial Infarction
- Trial name
- NCT00394680
- Volunteers
- 700 people
- Sponsor
- Shaare Zedek Medical Center
Coronary Artery Disease
Post-marketing Registry of Inspiron Sirolimus Eluting Coronary Stent
Post-marketing, prospective, multicentric, non-randomized registry to evaluate the safety and efficacy of Inspiron Sirolimus Eluting Coronary Stent at the treatment of "real-world" patients.
- Trial name
- Inspiron RL II (NCT03263260)
- Testing
- implant
- Where
- Brazil
- Volunteers
- 2,504 people
- Sponsor
- Scitech Produtos Medicos SA
Coronary Artery Disease
SMart Angioplasty Research Team: CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 3
This study is a prospective, open-label, two-arm, randomized multicenter trial to compare the efficacy and safety of clopidogrel versus aspirin monotherapy beyond the standard duration of dual antiplatelet therapy (DAPT) (more…
- Trial name
- SMART-CHOICE3 (NCT04418479)
- Testing
- Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 5,506 people
- Sponsor
- Joo-Yong Hahn