Clinical trials: Coronary Stent Occlusion
Coronary Artery Disease, Coronary Stent Occlusion
Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation
It is universally accepted that high-pressure balloon inflation is required to most effectively deploy a coronary balloon-expandable stent.
- Trial name
- INFLATION/DE (NCT01952873)
- Testing
- Prolonged inflation, Rapid inflation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Central Arkansas Veterans Healthcare System
Coronary Artery Disease
Intracoronary Stenting and Additional Results Achieved by ShockWAVE Coronary Lithotripsy
The clinical trial is intended to evaluate the efficacy, safety and economic benefit of coronary lithotripsy compared to other additional procedures (cutting or super high pressure balloon angioplasty, ablative procedures) in…
- Trial name
- ISAR-WAVE (NCT06369142)
- Testing
- Intravascular lithotripsy (IVL), Standard non-IVL methods
- Where
- 22 sites in Germany
- Volunteers
- 666 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease
Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent and Platelet AggregatioN studIeS for TreatMent of Acute Myocardial InfarctionTreatment of ST-elevation Acute Myocardial Infarction
To treat patients with acute myocardial infarction, primary percutaneous coronary intervention (PCI) will be performed with the use of an everolimus-eluting cobalt- chromium stent (everolimus-eluting stent: EES, Xience Prime…
- Trial name
- MECHANISM-AMI (NCT02014753)
- Testing
- cobalt-chromium everolimus-eluting stent (CoCr-EES)
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Iwate Medical University
Coronary Artery Occlusive Disease
A Trial Comparing the Effect of Pravastatin and Rosuvastatin on Atherosclerosis Progression Measured by Carotid Intima Media Thickness in Patients With Coronary Artery Disease After Biolimus Eluting Stent (Nobori®) Implantation: CPR IMT
Current consensus papers recommend statin medication to reduce Low density lipoprotein (LDL) cholesterol level less than 100mg/dL (optional 70mg/dL) in patients with coronary artery disease.
- Trial name
- NCT01872845
- Testing
- Pravastatin 40mg, Rosuvastatin
- Where
- South Korea
- Volunteers
- 671 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Coronary Stent Occlusion
DXR Stent for Vascular Healing and Thrombus Formation: OCT Study
The purpose of this study is to evaluate the efficacy of a novel dual drug-eluting stent (DXR stent), which slowly releases both cilostazol and paclitaxel, for strut coverage, malapposition, and thrombus formation, assessed by an…
- Trial name
- NCT02932995
- Where
- 6 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Chung-Ang University
Pulmonary Stenosis
Pulmonary Arteriopathy-Diagnostics and Therapy
Postoperative stenoses of the pulmonary artery vascular system seldom occur alone; they are frequently found in connection with congenital heart defects or malformation syndromes.
- Trial name
- NCT00266175
- Where
- 5 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Competence Network for Congenital Heart Defects
Coronary Artery Disease, Percutaneous Coronary Intervention
Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy
The primary aim of this study is to evaluate the efficacy and safety of novel P-CAB (tegoprazan 50 mg once daily) as compared with standard PPI (rabeprazole 20 mg once daily) for protection of GI events in patients with known…
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- PROTECT-HBR (NCT04416581)
- Testing
- PPI, P-CAB 50
- Where
- 45 sites in South Korea
- Volunteers
- 3,320 people
- Sponsor
- Duk-Woo Park, MD
Coronary Artery Disease
FFR vs. icECG in Coronary Bifurcations
The study hypothesis: it is possible to use icECG recorded from regular PCI wire to predict significance of SB ostial stenosis after main vessel stenting in coronary bifurcation lesions.
- Trial name
- FIESTA (NCT01724957)
- Testing
- Intracoronary ECG
- Where
- 2 sites in United States, Bulgaria
- Volunteers
- 37 people
- Sponsor
- University National Heart Hospital
Coronary Artery Disease
Vascular Response of Orsiro vs. Xience Drug-Eluting Stents for Treating Coronary Bifurcation Lesions
This study aims to compare vessel response and clinical outcomes of a biodegradable-polymer, ultra-thin strut, drug-eluting stent (Orsiro, Biotronik) and a durable-polymer, thin-strut, drug-eluting stent (Xience, Abbott) for the…
- Trial name
- NCT05200637
- Testing
- Orsiro stent, Xience stent, Any drug-eluting stent
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Coronary Artery Disease, Acute Coronary Syndrome
A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
PCI is considered as the reperfusion strategy of choice for patients with acute STEMI. Data from RCTs and meta-analyses demonstrate a consistent and strong signal towards a significant reduction in MACE among patients with STEMI…
- Trial name
- BIOSTEMI (NCT02579031)
- Testing
- Orsiro, Xience
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Stenosis, Coronary Arteriosclerosis
XIENCE V: SPIRIT WOMEN Sub-study
The purpose of this Clinical Evaluation is the continued assessment of the XIENCE Everolimus Eluting Coronary Stent System (XIENCE V® and XIENCE PRIME™ EECSS) with the primary focus on clinical outcomes in the treatment of female…
- Conditions
- Coronary Artery Stenosis, Coronary Arteriosclerosis, Coronary Artery Disease, Coronary Artery Restenosis
- Trial name
- NCT01182428
- Testing
- XIENCE V®/ XIENCE PRIME™, CYPHER SELECT
- Where
- 25 sites in Argentina, Austria and 13 more
- Volunteers
- 455 people
- Sponsor
- Abbott Medical Devices
Atherosclerosis
PE PREMIER CHINA CLINICAL TRIAL
PE PREMIER China: A Prospective, Multicenter Trial to Assess the Promus PREMIERTM Everolimus-Eluting Platinum Chromium Coronary Stent System for the Treatment of Atherosclerotic Lesion(s)
- Trial name
- NCT02230254
- Testing
- Percutaneous coronary intervention PROMUS PREMIER
- Volunteers
- 101 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease
Aroxxen® Inhalation for Cardioprotection After Elective PCI With Stent Implantation
This is an open-label, randomized, multicenter Phase II clinical study designed to evaluate the cardioprotective effect, to determine the optimal dosages and duration of inhalation, and to assess the clinical safety of the…
- Trial name
- NCT07397351
- Testing
- Aroxxen
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- Research Institute of Geroprotective Technologies
Coronary Artery Disease, Acute Myocardial Infarction
Drug-coated Balloon Versus Drug-eluting Stent in Acute Myocardial Infarction
Rationale: Compared with balloon angioplasty, implantation of bare metal stents (BMS) and drug eluting stents (DES) have shown to reduce repeat target lesion revascularization in primary percutaneous coronary intervention (PPCI).
- Trial name
- REVELATION (NCT02219802)
- Testing
- Treatment according arm
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Coronary Artery Disease
Study of the 2.25mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions
The main objective of this study is to assess the safety and effectiveness of the sirolimus-eluting Bx VELOCITYTM stent in reducing in-lesion restenosis in patients with de novo native coronary artery lesions.
- Trial name
- NCT00232739
- Testing
- CYPHER Sirolimus-eluting Coronary Stent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cordis US Corp.
Coronary Artery Disease, Stents
P2Y12 Inhibitor Monotherapy Versus Extended DAPT in Patients Treated With Bioresorbable Scaffold
This study aimed to compare the efficacy and safety of P2Y12 inhibitor monotherapy versus extended dual antiplatelet therapy (DAPT) following 12-month of DAPT in patients undergoing percutaneous coronary intervention (PCI) with…
- Conditions
- Coronary Artery Disease, Stents, Atherosclerosis
- Trial name
- SMART-CHOICEII (NCT03119012)
- Testing
- Clopidogrel, Ticagrelor, Aspirin
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Comparison Between P2Y12 Antagonist Monotherapy and Dual Antiplatelet Therapy After DES
To compare the efficacy and safety of clopidogrel monotherapy versus aspirin plus P2Y12 antagonist following 3-month of DAPT in patients undergoing PCI with DES.
- Trial name
- SMART-CHOICE (NCT02079194)
- Testing
- P2Y12 antagonist monotherapy, aspirin plus P2Y12 antagonist
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Optical Coherence Tomography
Efficacy and Safety of Zotarolimus-eluting Stent Overexpansion With OCT
Investigators aimed to evaluate efficacy and safety of expansion capacity of zotarolimus-eluting Stent assessed by optical coherence tomography (OCT) in vivo study.
- Conditions
- Coronary Artery Disease, Optical Coherence Tomography, Stent
- Trial name
- ONYSOVER (NCT05340361)
- Testing
- Optical coherence tomography-guided percutaneous coronary intervention, Optical coherence tomography-guided Onyx family stent expansion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Compare the Safety and Effectiveness of Genoss® DCB and SeQuent® Please NEO in Chinese Patients with Coronary ISR
The purpose of this study is to evaluate the safety and effectiveness of Genoss® DCB by demonstrating non-inferiority in patients with in-stent restenosis (ISR) compared with a product of the same category (Sequent® Please NEO).
- Trial name
- NCT04767022
- Testing
- Paclitaxel Coated PTCA Balloon Catheter(Genoss® DCB), Paclitaxel Coated PTCA Balloon Catheter(SeQuent® Please NEO)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Genoss Co., Ltd.