Clinical trials: Corticosteroid Injection
Asthma
Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate
This study is to find out if an Extra Virgin Olive-Oil-based Water (EVOOW) mix, removes more Fluticasone Propionate (FP) from the mouth than Water alone.
- Trial name
- EVOOW (NCT07664527)
- Testing
- Fluticasone Propionate, Water Mouthwash, EVOOW Mouthwash
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Full-thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections
The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study.
- Trial name
- NCT04895280
- Testing
- Ketorolac, Marcaine, Kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Khazzam
Degenerative Joint Disease
Platelet-Rich Plasma vs Corticosteroid Injection as Treatment for Degenerative Pathology of the Temporomandibular Joint
1.0 BACKGROUND AND HYPOTHESES 1.1 Osteoarthritis is a continuous and entirely physiologic adaptive process that occurs in every joint.
- Trial name
- NCT01920373
- Testing
- Group A (corticosteroid injection group), Group B (platelet rich plasma injection group)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Full Thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial
The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study.
- Trial name
- NCT04115644
- Testing
- Ketorolac, Kenalog
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Michael Khazzam
Physical Activity
Effects of Hyaluronic Acid vs. Hyaluronic Acid on Knee Osteoarthritis
Using double blind, randomized controlled design to study the immediate, short-term and intermediate-term therapeutic effects of ultrasound guided hyaluronic acid injection and hyaluronic acid combined corticosteroid injection to…
- Trial name
- NCT02625727
- Testing
- hyaluronic acid, hyaluronic acid combined corticosteroid
- Where
- Taiwan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Preterm Pregnancy, Antenatal Corticosteroid
The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the…
- Conditions
- Preterm Pregnancy, Antenatal Corticosteroid, Perinatal Problems
- Trial name
- NCT06164080
- Testing
- participants receiving Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Atrial Fibrillation
Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery
Atrial fibrillation is the most common arrhythmia to occur after cardiac surgery. Inflammatory response may be one etiological factor.
- Trial name
- NCT00442494
- Testing
- intravenous hydrocortisone
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Acute Respiratory Distress Syndrome
Corticosteroid Treatment for Acute Respiratory Distress Syndrome
It is acknowledged that IL-18, as a product of the inflammasome, is involved in host defence against viral and bacterial stimuli by modulating the immune response.
- Trial name
- NCT02819453
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
AZD8871 is a new chemical entity possessing long-acting effect in a single molecule which presents a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an…
- Trial name
- NCT02814656
- Testing
- AZD8871
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gonarthrosis; Primary
Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis
Methodology: Randomized double-blind clinical trial comparing intra-articular injection of Platelet-Rich Fibrin (PRF) versus intra-articular injection of corticosteroids in mild to moderate arthrosis of the knee.
- Trial name
- iPRF (NCT06905860)
- Testing
- Platelet-rich fibrin (PRF), Corticosteroid
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Allergic Asthma
House Dust Mite Induced Inflammasome Activation on Corticosteroid Resistance
In this project, PBMCs will be isolated from HDM allergic and non allergic patient and then stimulated with HDM crude extract. The expression of inflammasome and the correlation of inflammasome activation and steroid resistance…
- Trial name
- NCT03307278
- Testing
- House dust mite
- Volunteers
- healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Osteoarthritis Knee, Corticosteroid
Intra-articular Platelet Rich Plasma vs Corticosteroid in Treatment of Knee Osteoarthritis Patients
Knee osteoarthritis is the most common type of osteoarthritis in the lower extremity and constitutes 23% of all arthritis cases, about 13% of females and 10% of males aged above 60 years have symptomatic knee OA.
- Conditions
- Osteoarthritis Knee, Corticosteroid, Platelet Rich Plasma
- Trial name
- NCT05742061
- Testing
- Corticosteroid, Platelet Rich Plasma
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Arthroscopic Shoulder Surgery, Intra-articular Debridement
Intra-Operative Corticosteroid Injection During Arthroscopic Shoulder Surgery
The purpose of this study is to assess the efficacy of intra-operative subacromial corticosteroid injections in patients undergoing arthroscopic shoulder surgery on quality of life scores and activity level when compared to a…
- Conditions
- Arthroscopic Shoulder Surgery, Intra-articular Debridement, Subacromial Decompression, Acromioplasty
- Trial name
- NCT02867904
- Testing
- Methylprednisolone (40 mg depomedrol, 1ml, injection), Marcaine (4ml 0.5%, injection)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Peter Chang
Trigger Finger, Pain
Using the Gate Control Theory of Pain to Decrease Pain During Trigger Finger Corticosteroid Injections
The goal of this clinical trial is to investigate a new noninvasive technique that patients may use to help reduce the pain that they experience during cortisone injections for trigger fingers.
- Trial name
- TFGCT (NCT06401473)
- Testing
- Ipsilateral Scratch Task, Motor Distraction Task
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Grand Canyon University
Asthma
Inflammation and Corticosteroid Responsiveness in Severe Asthma
Some patients with mild asthma may develop severe asthma. It is not known what makes patients with mild asthma become severe, and we plan to find out why this happens.
- Trial name
- SARP (NCT00180661)
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma
Molecular Mechanism of Asthma
The aim of this study is to investigate the mechanisms whereby lung function is decreased in asthma and sensitivity to treatment.
- Trial name
- NCT00180726
- Testing
- Blood sampling, Endoscopic Bronchoscopy, Spirometry
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Psoriasis
Conditioning, the Placebo Effect, and Psoriasis
This study uses the psychological principle known as classical conditioning to try to improve the standard treatment of psoriasis.
- Trial name
- NCT00005922
- Testing
- Partial schedule of pharmacotherapeutic reinforcement, Dose control for Arm B, Standard pharmacotherapeutic protocol
- Where
- 2 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Patients With Systemic Inflammatory Diseases Receiving for the First Time a Protracted General Corticostroid Therapy
Impact of Systemic Corticosteroid Therapy on Lens Transparency and Quantification of Lens Autofluorescence.
Corticosteroid therapy is usually regarded as a risk factor for the development of posterior subcapsular cataracts but prospective studies on this topic and accurate assessment of this potential adverse effect are lacking.
- Trial name
- NCT00337623
- Testing
- Prednisolone
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Asthma
Asthma Biomarkers for Predicting Response to Therapy
Novel asthma biomarkers to predict the response to inhaled corticosteroid Brief description: This will be a single center study of asthmatic subjects and healthy controls which will investigate mechanisms underlying different…
- Trial name
- NCT01973751
- Testing
- Budesonide
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Knee Osteoarthritis
Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
Knee osteoarthritis (OA) causes patients considerable joint pain and leads to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03379168
- Testing
- Microfragmented Adipose Tissue (Lipogems), Corticosteroid injection, Saline
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dustin L. Richter, MD