Clinical trials: Cost Effectiveness
Oral Cancer, Psychological Distress
Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer
The goal of this clinical trial is to develop and evaluate an Artificial Intelligence Assisted Prehabilitation Program (AI APP) for returning to work and cost-effectiveness analysis in patients with oral cancer (OC).
- Conditions
- Oral Cancer, Psychological Distress, Communication Aids for Disabled, Physiotherapy
- Trial name
- NCT07562100
- Testing
- Prehabilitation application, Conventional physiotherapy, Scar management
- Where
- 5 sites in Taiwan
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Mental Health, Stress Disorders, Post-Traumatic
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
The primary study objective is to conduct a prospective, randomized controlled clinical trial that compares the effectiveness of two approaches for delivering smoking cessation treatment for veterans with posttraumatic stress…
- Conditions
- Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
- Trial name
- NCT00118534
- Testing
- Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Scar
Comparison of Lasers in the Treatment of Scars
The purpose of this study is to compare the 1550-nm non-ablative Fraxel laser (referred to as Fraxel Laser in this application) to the ablative 10,600-nm carbon dioxide fractional laser (referred to as CO2 Laser in this…
- Trial name
- NCT02988622
- Testing
- Fraxel Laser, CO2 Laser
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marta Hemmingson-Van Beek
Primary Infertility, Secondary Infertility
Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF
The purpose of this study to evaluate a low cost minimal stimulation protocol combined with Intravaginal Culturing, to make IVF affordable and available across the large infertile/subfertile population
- Conditions
- Primary Infertility, Secondary Infertility, Low Responders, Mild to Moderate Male Factor Infertility
- Trial name
- MSP-INVO IVF (NCT01058252)
- Testing
- INVOCell, Letrozole 2.5 mg, recFSH 75 IU, STEP-3: LH Suppression & Monitoring, STEP-4: HCG Timing
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galaxy Pharma (Pvt) Limited
Ectopic Tooth Eruption, Palatal Expansion Technique
The Effectiveness of Early Intervention to Correct the Position of PDC:s
Approximately 2-3% of children will have problems with one or both of their permanent or 'adult' canine teeth in the upper jaw. These canine teeth sometimes fail to erupt properly, because they are displaced into the roof of the…
- Conditions
- Ectopic Tooth Eruption, Palatal Expansion Technique, Randomized Clinical Trial
- Trial name
- PDC (NCT06267989)
- Testing
- Extraction of the primary canine teeth, Expansion
- Where
- 3 sites in Germany, Sweden and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Göteborg University
HIV Infections
Use of HIV Self-Test Kits to Increase Identification of HIV-Infected Individuals and Their Partners
This study comprises two trials to evaluate the feasibility and cost-effectiveness of HIV self-testing strategies compared to standard of care among clients in outpatient departments (OPD; Aim 1) and the sexual partners of…
- Trial name
- NCT03271307
- Testing
- Optimized PITC, Facility HIVST, Index HIVST
- Where
- Malawi
- Volunteers
- 6,369 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Malaria
Spatial Repellents for Malaria Control
The primary objective of the study is to demonstrate and quantify the effectiveness of a spatial repellent (SR) product, in reducing malaria infection in humans under operational program conditions in a humanitarian assistance…
- Trial name
- AEGIS Uganda (NCT06122142)
- Testing
- Transfluthrin - delivery by paid study personnel, Transfluthrin - delivery by voucher system, Transfluthrin - delivery by village health teams
- Where
- 2 sites in Uganda
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Notre Dame
Perineal Infection, Maternal Infections Affecting Fetus or Newborn
Different Perineal Preparations Before Vaginal Birth to Maternal/Neonatal Infections and Cost Effectiveness
The vaginal microbiome plays a crucial role in women's health, primarily composed of beneficial bacteria such as Lactobacillus, which help maintain an acidic environment in the vagina, preventing the growth of pathogens.
- Conditions
- Perineal Infection, Maternal Infections Affecting Fetus or Newborn, Cost Effectiveness
- Trial name
- NCT06880445
- Testing
- Povidone-Iodine (PVP-I), Water
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tzu-Ying Huang
Neoplasms, Communication
My Team of Care: a Pilot Randomized Controlled Trial of an Online Communication Tool for Collaborative Care
This project will pilot and test a new online communication tool, Loop, developed within a research framework with participatory and user-centred design. This pilot trial focuses on advanced cancer as an example of complex care.
- Trial name
- Loop (NCT02372994)
- Testing
- Loop
- Where
- 2 sites in Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Vaccination Behavior
Child Vaccination Scheduling in China
This study aims to optimize pediatric vaccine scheduling in China . The first objective is to gather information on current vaccine schedules in China.
- Trial name
- NCT07141875
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Rehabilitation, Spinal Fusion
Effect of a Case Manager to Assist the Rehabilitation for Lumbar Spinal Fusion Patients. A Randomised Controlled Trial.
The aim of the current study is to examine the effect of a case manager-assisting rehabilitation program compared to usual physical rehabilitation for patients undergoing a lumbar spinal fusion on functional disability, pain, and…
- Conditions
- Rehabilitation, Spinal Fusion, Case Managers
- Trial name
- NCT03433443
- Testing
- Case manager assisted rehabilitation, Usual physical rehabilitation
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diarrhoea;Infectious;Presumed, Diarrhea, Infantile
Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa
This project is a community-based randomized controlled trial designed to test the effectiveness of two point-of-use water treatment technologies to improve clean drinking water access, reduce enteropathogen burden, and improve…
- Conditions
- Diarrhoea;Infectious;Presumed, Diarrhea, Infantile, Diarrhea Tropical, Environmental Exposure
- Trial name
- NCT03012048
- Testing
- Silver-impregnated ceramic tablet, Silver-impregnated ceramic water filter, Safe-storage water container
- Where
- South Africa
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Frailty, Ageing Well
Healthy Older Adults Through Movement and Engagement
The HOME Project evaluates the effects of structured health dialogues with individuals aged 67-84 years in the municipality of Borgholm, Sweden.
- Conditions
- Frailty, Ageing Well, Prevention Intervention, Health Related Quality of Life
- Trial name
- HOME (NCT07136168)
- Testing
- Health dialogue
- Where
- Sweden
- Volunteers
- 2,952 people, healthy volunteers welcome
- Sponsor
- Linkoeping University