Clinical trials: Cost-Effectiveness
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda
The use of insecticide-treated bed nets (ITNs) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance in mosquito populations to commonly used insecticides.
- Trial name
- NCT04230161
- Testing
- Standard long-lasting insecticidal net, Chlorfenapyr insecticide treated net, Indoor residual spraying
- Where
- Rwanda
- Volunteers
- 3,502 people, healthy volunteers welcome
- Sponsor
- PATH
Lung Cancer
Respiratory Distress Symptom Intervention (RDSI) Trial
This study aims to determine the effects of adding the Respiratory Distress Symptom Intervention (RDSI) to usual care for the self management of the Respiratory Distress Symptom Cluster (breathlessness-cough-fatigue) for patients…
- Trial name
- RDSI-LC (NCT03223805)
- Testing
- Respiratory Distress Symptom Intervention
- Where
- 7 sites in United Kingdom
- Volunteers
- 263 people
- Sponsor
- The Christie NHS Foundation Trust
Resuscitation
Out-of-Hospital Resuscitation in Winterthur - an Outcome Study
The investigators will retrospectively examine all patients with out-of-hospital resuscitation by the emergency medical Team (EMT) from the Kantonsspital Winterthur in the year 2013 with a two year follow-up and a structured…
- Trial name
- NCT02625883
- Testing
- Interview
- Volunteers
- 151 people
- Sponsor
- Kantonsspital Winterthur KSW
Oral Hygiene, Intensive Care
Effect of Toothbrushing Without Chlorhexidine on Oral Hygiene Indices in Patients With Orotracheal Intubation
The oral hygiene method commonly used in intubated patients orotracheal is tooth brushing (mechanical removal) and washing the oral cavity and the orotracheal tube (TOT) with digluconate solution chlorhexidine (CLX).
- Conditions
- Oral Hygiene, Intensive Care, Chlorhexidine
- Trial name
- NCT06453122
- Testing
- Oral care
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Heart Failure
SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.
- Trial name
- SAFE-HOME (NCT03156686)
- Testing
- HOME-based hospitalization
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- French Cardiology Society
Lung Cancer
Paclitaxel With or Without Carboplatin in Treating Patients With Advanced Non-small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003117
- Testing
- carboplatin, paclitaxel
- Where
- 35 sites in United States
- Volunteers
- 584 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Safety, Efficacy
Misodel or Angusta for Induction of Labour?
In Denmark, every 4 birth induced, most often due to prolonged pregnancy, up til 10-12 days after term. A group (RADS) set up by the Danish Regions has recently recommended induction with prostaglandins in tablet form (Angusta®).
- Conditions
- Safety, Efficacy, Cost, Experience
- Trial name
- NCT02693587
- Testing
- Misodel and Angusta
- Where
- Denmark
- Volunteers
- 420 people
- Sponsor
- Holbaek Sygehus
Type 2 Diabetes Mellitus
Cost Effectiveness of Glargine Insulin Versus NPH Insulin
Glycemic control is fundamental in the management of diabetes mellitus .If lifestyle intervention and full tolerated doses of one or two oral glucose lowering drugs (OGLDs) fail to achieve or sustain glycemic goals, insulin…
- Trial name
- NCT01832935
- Testing
- insulin glargine, Insulin NPH
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Tehran University of Medical Sciences
Cancer Survivors, Return to Work
Enhancing Work Participation of Unemployed and Work-Disabled Cancer Survivors
The primary objective of this study is to evaluate the effectiveness of the PLACES intervention on paid employment re-entry in unemployed and work-disabled cancer survivors, compared to CAU.
- Trial name
- PLACES (NCT06028048)
- Testing
- PLACES
- Where
- 2 sites in Netherlands
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Malaria
Cost-effectiveness Evaluation of Vector Control Strategies in Mozambique
This study aims to provide National Malaria Control Programs (NMCP), international donors and other key stakeholders with clear evidence on the impact and cost-effectiveness of using indoor residual spraying (IRS) with a…
- Trial name
- COST (NCT02910934)
- Testing
- Actellic CS
- Where
- 2 sites in United States, Mozambique
- Volunteers
- 3,915 people, healthy volunteers welcome
- Sponsor
- PATH
Visceral Leishmaniasis, Kala Azar
Efficacy, Acceptability and Cost-effectiveness of Long Lasting Insecticide Nets (LLIN) in the Prevention of Kala Azar
A cluster-randomized vector control trial in Bihar, India, and neighboring Nepal, will test the efficacy of long-lasting impregnated bednets (LLINs, Permanets) for reducing visceral leishmaniasis incidence.
- Trial name
- KALANET (NCT00318721)
- Testing
- Long Lasting Impregnated Nets (LLIN)
- Where
- 2 sites in India, Nepal
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Diabetes Mellitus, Type 2
Scripps Digital Diabetes: Cloud-Based Continuous Glucose Monitoring (CB CGM)
Individuals with diabetes in the hospital often experience poor glycemic control, which places them at greater risk for infection, neurological and cardiac complications, mortality, longer lengths of stay, readmissions, and…
- Trial name
- NCT04269655
- Testing
- Cloud-Based Continuous Glucose Monitoring
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Scripps Whittier Diabetes Institute
Ventilator Acquired Pneumonia
Cost Effectiveness Of Linezolid In Central America
The therapy with Linezolid (LIN) represents better cost-effectiveness vs. Vancomycin (VAN) for the treatment of nosocomial Pneumonia associate to ventilator (VAP).
- Trial name
- NCT01040585
- Testing
- Linezolid
- Sponsor
- Pfizer
Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorder
Randomized Controlled Trial of Comet Via the Internet or in Group Format.
The Comet-program is a Swedish parent training program developed to target externalizing behaviors in children between 3-11 years.
- Trial name
- NCT03465384
- Testing
- Comet
- Where
- 7 sites in Sweden
- Volunteers
- 161 people
- Sponsor
- Karolinska Institutet
Posttraumatic Stress Disorder (PTSD), Depression
Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial
The overall objective of this study is to test the effectiveness of a systems-level approach to primary care recognition and management of PTSD and depression in the military health system.
- Trial name
- STEPS UP (NCT01492348)
- Testing
- STEPS UP, OUC
- Where
- 6 sites in United States
- Volunteers
- 666 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Graves Disease
The Impact of Person Centred Care (PCC) in Grave's Disease
Mental fatigue (MF) is prevalent after Graves' disease (GD), which is the most common form of hyperthyroidism. We have reported that 38% of patients, compared to 11% of control subjects, suffer from MF more than 1 year after…
- Trial name
- NCT06309316
- Testing
- Person-centred care (PCC)
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Vastra Gotaland Region
Hypertension
A Comparison of Telemedical and Conventional Antihypertensive Treatment
The aim of the study is to compare telemedical antihypertensive treatment based on home blood pressure monitoring and conventional antihypertensive treatment based on monitoring of blood pressure in the doctor's office.
- Trial name
- NCT00282334
- Testing
- Telemedical blood pressure monitoring
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Regional Hospital Holstebro
Caregiver Burden, Financial Stress
CONFIDENCE Financial Education for Caregivers
The purpose of this study is to determine how feasible it is to deliver an online course to reduce out-of-pocket costs of caregiving and reduce financial stress among Latino family caregivers to a family member living with…
- Conditions
- Caregiver Burden, Financial Stress, Dementia, Alzheimer Disease
- Trial name
- CONFIDENCE (NCT05292248)
- Testing
- Confidently Navigating Financial Decisions and Enhancing Financial Wellbeing in Dementia Caregiving
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Pneumonia - Bacterial
Impact of BioFire FilmArray Pneumonia Panel vs Routine Diagnostics on Antimicrobial Outcomes (DOOR-MAT)
Multidrug-resistant bacterial infections are a growing global health concern. Hospital-acquired pneumonia is one of the most common infections occurring during hospitalization and can be associated with high mortality, reaching…
- Trial name
- NCT07585604
- Testing
- Multiplex PCR-based pneumonia panel (BIOFIRE® FILMARRAY® Pneumonia Panel)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
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