Clinical trials: Cost-effectiveness
Frail Older Adults
Is Multifactorial Nutritional Treatment for Undernutrition in Older Adults in Primary Care Cost-effective?
The hypothesis is that there is a profit potential by implementing a multifactorial nutritional intervention among frail elderly since this will result in an improved nutritional status, functional capacity and improved quality…
- Trial name
- CES (NCT01873456)
- Testing
- multifactorial nutritional intervention
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Obesity
Evaluation of an Enhanced Delivery Model for Go NAPSACC
This study will compare the effectiveness and cost of Basic and Enhanced delivery models for Go NAPSACC on child care centers' use of evidence-based nutrition and physical activity practices.
- Trial name
- NCT03938103
- Testing
- Enhanced Go NAPSACC, Basic Go NAPSACC
- Where
- 2 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hepatitis C
Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil)
Up to 650,000 people in Brazil are living with chronic hepatitis c virus (HCV) infection. Hepatitis C is a silent disease, and up to 20% of cases can progress to liver cirrhosis and its complications.
- Trial name
- HCVPCL05/20 (NCT06306300)
- Testing
- Specialist - Epclusa 400Mg-100Mg Tablet, Non- specialist - Epclusa 400Mg-100Mg Tablet, HCV Self-Testing kit (Ora-Quick HCV ST or Wond-Foo HCV ST)
- Where
- 2 sites in Brazil
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Breast,Hypertrophy, Cost-effectiveness
Cost-effectiveness of Reduction Mammaplasty
Several works show breast hypertrophy as pain cause, postural alterations, dermatitis and decrease of the functional capacity and of the self-esteem.
- Trial name
- NCT00992368
- Testing
- reduction mammaplasty
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cholera
Cholera Vaccine Investment Strategy in Bangladesh
To evaluate the preventive impact, demand, acceptability, uptake, feasibility, and cost-effectiveness of a two-dose regimen of the OCV Shanchol in children living in urban slums in Bangladesh, Investigators will conduct a…
- Trial name
- CVIS (NCT02727855)
- Testing
- Shanchol
- Where
- Bangladesh
- Volunteers
- 75,170 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Primary Infertility, Secondary Infertility
Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF
The purpose of this study to evaluate a low cost minimal stimulation protocol combined with Intravaginal Culturing, to make IVF affordable and available across the large infertile/subfertile population
- Conditions
- Primary Infertility, Secondary Infertility, Low Responders, Mild to Moderate Male Factor Infertility
- Trial name
- MSP-INVO IVF (NCT01058252)
- Testing
- INVOCell, Letrozole 2.5 mg, recFSH 75 IU, STEP-3: LH Suppression & Monitoring, STEP-4: HCG Timing
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galaxy Pharma (Pvt) Limited
Schizophrenia
Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia
Schizophrenia is a severe psychotic illness of unknown cause that affects 1% of the population worldwide. Currently, there is no diagnostic test for schizophrenia.
- Trial name
- NCT03781115
- Testing
- Ziprasidone, Olanzapine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Human Immunodeficiency Virus
Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
Having health workers assist HIV-infected persons with the recruitment and testing of their sexual contacts and biological children is an effective and efficient way of identifying additional HIV-infected persons in need of HIV…
- Trial name
- PRACTICE (NCT05343390)
- Testing
- Enhanced implementation package, Standard implementation package
- Where
- 33 sites in Malawi
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Uterine Cervical Neoplasms
Economic Evaluation of Three Populational Screening Strategies for Cervical Cancer
The aim of this study was to compare the effectiveness and the costs of three types of population interventions to increase the number of female participants in the screening programmes for cancer of the cervix carried out by…
- Trial name
- CRICERVA (NCT01373723)
- Testing
- Different alternatives to improve the coverage of the populational screening programmes of cervical cancer
- Where
- Spain
- Volunteers
- 20,994 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cost, Problem-based Learning
Efficacy of Near-Assisted Learning (NAL) in Improving Students' Objective Structured Clinical Examination (OSCE) Grades
This study aims to evaluate the impact of near-assisted learning (NAL) on first-year medical students' objective structured clinical examination (OSCE) grades in a problem-based learning (PBL) environment.
- Conditions
- Cost, Problem-based Learning, Peer Group
- Trial name
- SRMC (NCT04177979)
- Testing
- Near-assisted learning through trained peers
- Where
- Saudi Arabia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sulaiman AlRajhi Colleges
Pregnancy
Home Based Life Saving Skills Training in a Rural Area in Tanzania
Background The maternal mortality ratio in Tanzania has been persistently high for ten years with no signs of the ratio going down.The Tanzania Demographic and Health Survey (TDHS) of 1999 and 2005 estimate the maternal mortality…
- Trial name
- HBLSS (NCT01192646)
- Testing
- HBLSS
- Where
- Tanzania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Muhimbili University of Health and Allied Sciences
Dental Caries
Cost-effectiveness of Four Methods in Preventing Fissure Caries in Permanent Teeth
The aim of this proposed study is to investigate the cost-effectiveness of four methods in preventing fissure caries in permanent teeth, which is the most prevalent dental disease in primary school children in China.
- Trial name
- NCT01829334
- Testing
- ART dental sealant, Resin dental sealant, Sodium fluoride varnish
- Where
- China
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Carious Primary Molars
Clinical And Cost- Effectiveness of Allium Sativum Oil (Garlic Oil ) Versus Mineral Trioxide Aggregate in Primary Molars Pulpotomy in Group of Egyptian Children : A Randomised Clinical Pilot Study.
Allium Sativum oil is advocated to prove the capability of new natural products in replacing higher cost pharmacological materials, while achieving the same successful clinical and radiographic long-term results.
- Trial name
- NCT04903808
- Testing
- Allium Sativum Oil, Mineral Tri-Oxide Aggregate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Cancer
Using Technology to Scale-Up an Occupational Sun Protection Policy Program
Comprehensive approaches that combine sun protection policy and education for outdoor workers can reduce their risk for skin cancer by reducing their exposure to solar ultraviolet radiation on the job.
- Trial name
- SSW-T (NCT03278340)
- Testing
- Sun Safe Workplaces - Technology, Sun Safe Workplaces -In Person
- Where
- 2 sites in United States
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Smoking Cessation
A Cost-effectiveness Study of Nicotine Patches Distributed Through a Quitline
The study is to understand whether distribution of two different supplies of nicotine patches through a telephone quitline has an effect on quit rates. The two different supplies are four vs.
- Trial name
- NCT01889771
- Testing
- Nicotine Patch
- Volunteers
- 1,495 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Glass Ionomer Cement, Cost-effectiveness
Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant
Eruption of the first permanent molar is the earliest in our oral cavity, leading to a high occurrence of dental caries in its pits and fissures.
- Conditions
- Glass Ionomer Cement, Cost-effectiveness, Pit and Fissure Caries (Disorder)
- Trial name
- NCT03034837
- Testing
- resin sealant, ART sealant
- Where
- 2 sites in China
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Zhengzhou University
Cost Effectiveness
Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant (Part 2)
The aim of the present study is determine the cost-effectiveness, clinical- effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted…
- Trial name
- NCT04793256
- Testing
- Fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride)., Resin based fissure sealant (3M Clinpro Sealant)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cairo University
Self Efficacy, Loneliness
Putting Life in Years (PLINY): Telephone Friendship Groups Research Study
The National Institute for Health Research commissioned this research with the following research question: "What is the relative effectiveness and cost effectiveness of home based support programmes in improving the mental…
- Trial name
- PLINY (NCT01754753)
- Testing
- Telephone Friendship groups
- Where
- United Kingdom
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Sheffield