Clinical trials: Cough Variant Asthma
Asthma
Prospective Clinical Study on the Clinical Efficacy and Prognostic Outcome of ICS/LABA Combined With Liqin Zhike Formula in the Treatment of Cough Variant Asthma
To investigate the impact of the combination of ICS/LABA and Liqin Zhike Formula on the clinical efficacy and prognostic outcomes of cough variant asthma.
- Trial name
- NCT07272278
- Testing
- ICS+LABA, Chinese Medicine Formula
- Volunteers
- 236 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bronchial Asthma
Treatment Efficacy of Budesonide/Formoterol in Cough Variant Asthma and Typical Asthma Patients
Bronchial asthma is a common respiratory disease characterized by chronic airway inflammation, which have been affecting about 1-18% of the population in the world, causing tremendous economic burden for the patients and…
- Trial name
- NCT02934945
- Testing
- budesonide 160μg/formoterol 4.5μg
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhujiang Hospital
Cough Variant Asthma
Non-Interventional Study of Cough Variant Asthma Treatment With Pulmicort®Respules® in Children Outpatients
This open label, non-interventional study is to show the efficacy of Pulmicort®Respules® in cough variant asthma in patient aged 5-year old or younger in outpatient department
- Trial name
- PUL NIS (NCT00660114)
- Where
- 32 sites in China
- Volunteers
- 914 people
- Sponsor
- AstraZeneca
URTI, Cough
Acoustic Analytic Apps for Smart Telehealth Screening - Creating a Big Data
To develop and validate a library of cough spectrum from a target of 1000 cough acoustics. Coughs arising from upper respiratory infection, lower chest infections, asthma, allergic conditions are included in the study.
- Conditions
- URTI, Cough, Cough Variant Asthma, Cough; Bronchial, With Grippe or Influenza
- Trial name
- NCT03169699
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Asthma, Cough Variant Asthma
Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge Tests
Cough is a common, disruptive and at times disabling symptom which often prompts patients to seek medical attention. Determining the cause(s) of chronic cough can be challenging, and costly.
- Trial name
- NCT01064245
- Testing
- high-dose methacholine challenge test, mannitol challenge test
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Dr. Diane Lougheed
Asthma
Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma
This study aims to observe the therapeutic effect of Su-Huang antitussive capsule on cough variant asthma. The investigators hypothesize: Cough score and cough reflex sensitivity will be improved after treatment with Su-Huang…
- Trial name
- NCT01584804
- Testing
- Su-Huang antitussive capsule, Sugar pill
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Asthma, Cough Variant Asthma
Optimal Type of Inhaler in Cough Variant- or Cough Predominant Asthma
Asthma management is based on inhaled therapy, mainly on inhaled glucocorticosteroids (ICS). The efficacy of inhaled therapy depends on type of inhaler and proper inhalation skills.
- Trial name
- NCT04203472
- Testing
- Budesonid or budesonide/fomoterol administered by DPI, Budesonid or budesonide/fomoterol administered by MDI
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Medical University of Warsaw
Cough Variant Asthma
Validity of Fractional Exhaled Nitric Oxide and Impulse Oscillometry in Patients With Cough Variant Asthma
The aim of the research is to evaluate the clinical value of fractional exhaled nitric oxide(FeNO) ,impulse oscillometry(IOS) and mid-expiratory flow (MEF) in patients with cough variant asthma.
- Trial name
- NCT03573284
- Testing
- fractional exhaled nitric oxide(FeNO), impulse oscillometry(IOS)
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Zhujiang Hospital
Asthma, Cough
Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol
The objectives of this study are to determine the sensory-mechanical responses to Eucapneic Voluntary Hyperventilation (EVH) and Mannitol in individuals with cough variant asthma (CVA) and methacholine-induced cough with normal…
- Conditions
- Asthma, Cough, Cough Variant Asthma
- Trial name
- NCT03105843
- Testing
- Methacholine (MCh) Challenge Testing, Eucapneic Voluntary Hyperventilation (EVH), Mannitol Inhalation Kit
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dr. Diane Lougheed
Cough Variant Asthma
The Efficacy of Budesonide/Formoterol in Cough Variant Asthma
Cough variant asthma (CVA), subtype of bronchial asthma, is considered to be one of the most common causes of chronic cough in different cough guidelines of United States, Europe, China and other countries.
- Trial name
- NCT04171180
- Testing
- budesonide/formoterol
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cough, Cough Variant Asthma
MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough
The aim of the study is to assess the prevalence of bronchial hyperresponsiveness (BHR) in non-smoking adults with chronic cough and the prevalence of BHR in patients with upper airway cough syndrome (UACS) and gastroesophageal…
- Conditions
- Cough, Cough Variant Asthma, Upper-Airway Cough Syndrome, GERD
- Trial name
- NCT03363698
- Testing
- Cough variant asthma treatment
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Medical University of Warsaw
Asthmatic Bronchitis
Gene Expression Profile and Inflammation Profile of Classic Asthma, Cough Variant Asthma and Eosinophilic Bronchitis
This study aims to identify and validate the gene expression differentials of peripheral blood mononuclear cells and differential inflammation profiles and other aspects in classic asthma, cough-variant asthma and eosinophilic…
- Trial name
- NCT02555345
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Eosinophilic Bronchitis, Cough Variant Asthma
The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma
This study aim is to observe the response to Bambuterol Hydrochloride tablets treatment in subjects with eosinophilic bronchitis .
- Trial name
- NCT02002754
- Testing
- Bambuterol Hydrochloride tablets
- Where
- China
- Volunteers
- 45 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Asthma, Cough
Bronchodilating and Bronchoprotective Effects of Deep Inspirations
The objectives of this research are to compare (i) the bronchodilating and (ii) the bronchoprotective effects of deep inspirations (DIs) in individuals with: (a) asthma, (b) CVA, (c) methacholine-induced cough but normal airway…
- Trial name
- NCT01659476
- Testing
- Methacholine(MCh) Challenge Testing
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cough-Variant Asthma
Establish FeNO Cut-off Value for Predicting Budesonide-formoterol Response in Chronic Cough Suggestive of CVA Patients.
This is a multicenter, prospective, single-arm, interventional clinical study to predict the response to budesonide-formoterol treatment in patients with chronic dry or nocturnal cough by determining a cut off value of FeNO.
- Trial name
- EFFICIENCY (NCT06590740)
- Testing
- Budesonide-Formoterol treatment
- Where
- 39 sites in China
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Asthma
Effects of Leukotriene Modulator Montelukast on Cough Variant Asthma
This study aims to observe the therapeutic effect of leukotriene modulator montelukast alone or combined with inhaled corticosteroid(ICS) on cough variant asthma(CVA). The investigators hypothesize: 1.
- Trial name
- NCT01404013
- Testing
- ICS/LABA, Montelukast, ICS/LABA and Montelukast
- Where
- China
- Volunteers
- 99 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cough Variant Asthma
Observation of Cough Variant Asthma Treated in Combination of Chanqin Granules.
This single-center, randomized, double-blind, placebo-controlled trial was undertaken at an outpatient clinic in Shuguang Hospital. Newly diagnosed cough variant asthma adult patients with the T.C.M.
- Trial name
- NCT03319043
- Testing
- Chanqin granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Cough Variant Asthma
Multicenter Clinical Study on the Optimal Treatment Protocol and Outcome of Cough Variant Asthma With Chinese and Western Medicine
To explore the disease outcome prognosis of cough variant asthma by observing the outcomes of cough variant asthma and the effects of Chinese and Western medicine interventions, and to provide a scientific basis for optimizing…
- Trial name
- NCT05459805
- Testing
- traditional chinese medicine Xuanfei-Zhike formula, inhaled corticosteroids (ICS) and long-acting β2-agonist (LABA)
- Where
- 4 sites in China
- Volunteers
- 164 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Asthma
A Case-control Study on the Differentiation Between Cough Variant Asthma and Chronic Cough
this study aimed to compare characters in pulmonary function of patients with cough variant asthma and chronic cough and establish a diagnostic model.
- Trial name
- NCT06199830
- Testing
- positive bronchial provocation test
- Where
- China
- Volunteers
- 645 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Cough Variant Asthma
Efficacy and Safety Study of Procaterol Hydrochloride to Treat Patients With Cough Variant Asthma (CVA)
The purpose of this study is to investigate the efficacy and safety of procaterol hydrochloride with inhaled glucocorticoid in treatment patients with cough variant asthma (CVA).
- Trial name
- NCT01170429
- Testing
- Procaterol hydrochloride
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine