Clinical trials: Covid-19 Pneumonia
Pneumonia, Viral, Cytokine Storm
Ultra Low Doses of Therapy With Radiation Applicated to COVID-19
The host response against the coronavirus 2 (SARS-CoV-2) appears to be mediated by a 'cytoquine storm' developing a systemic inflammatory mechanism and an acute respiratory distress syndrome (ARDS), in the form of a bilateral…
- Trial name
- ULTRA-COVID (NCT04394182)
- Testing
- Ultra-Low-dose radiotherapy, ventilatory support with oxygen therapy, Lopinavir/ritonavir
- Where
- 2 sites in Spain
- Volunteers
- 15 people
- Sponsor
- Fundacion GenesisCare
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Brain Imaging in Babies Study
The aims of the BIBS Study The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Conditions, COVID-19
- Trial name
- BIBS (NCT04443179)
- Where
- United Kingdom
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- King's College London
Wellbeing of Healthcare Providersin Frontline COVID-19 Departments
Integrative Medicine Impact on Frontline COVID-19 Personnel Wellbeing
Treating COVID-19 hospitalized patients incurred heavy burden of physical and emotional stress. The present study is taking place at Carmel Medical Center in collaboration with the integrative oncology and the internal medicine…
- Trial name
- NCT05104827
- Testing
- Complementary Integrative Medicine
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Carmel Medical Center
Acute Respiratory Distress Syndrome, SARS-CoV-2
Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease
Rationale: The current SARS-CoV-2 pandemic has a high burden of morbidity and mortality due to development of the so-called acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, SARS-CoV-2, COVID, COVID-19
- Trial name
- NCT04335786
- Testing
- Valsartan (Diovan)
- Where
- 7 sites in Netherlands
- Volunteers
- 23 people
- Sponsor
- Radboud University Medical Center
Covid-19
Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With Covid-19
Describes the cohort of patients receiving ECMO-VV or ECMO-VA in the management of severe ARDS refractory to SARS-CoV-2 in the Strasbourg and Louvain centres
- Trial name
- ECMO-SL-CoV-2 (NCT04446286)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Cerebral Palsy, Covid19
Rehabilitation Status of Children With Cerebral Palsy and Anxiety of Their Caregivers During the Covid19 Pandemic
Rehabilitation status of children with cerebral palsy (CP) and anxiety of their caregivers during the covid19 pandemic were explored.
- Conditions
- Cerebral Palsy, Covid19, Anxiety
- Trial name
- CP (NCT04916873)
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
COVID-19 Pneumonia
Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314
A Double-blind, Multi-center, Multi-regional, Randomized controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed with COVID-19
- Trial name
- NCT04871646
- Testing
- CKD-314+SOC
- Where
- South Korea
- Volunteers
- 586 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Covid19
Impact of Moderate Exercise Training on Vitals and Peak VO2 in Different Age Categories of Adult in COVID-19.
To determine the impact of moderate exercise training on vitals (BP, HR) in different age categories of adult in COVID-19. To determine the Impact of moderate exercise training on Peak VO2 in different age categories of adult in…
- Trial name
- NCT04927182
- Testing
- Moderate Exercise Training (Age Group 1; Young adult 17 -30 years), Moderate Exercise Training (Age Group 2; 31 to 45 years), Moderate Exercise Training (Age Group 3; Above 45 years)
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Riphah International University
Covid19, Cancer
Antibodies Production After Covid-19 Vaccination Among Patients With Medical History of Cancer and Anti-CD-20 Treatment
This is a Phase II study designed to investigate if the Covid 19 vaccines are capable of eliciting production of antibodies against S protein of Sar-S-Cov-2 virus among patients with medical history of cancer previously treated…
- Conditions
- Covid19, Cancer, HIV Infections
- Trial name
- NCT04779996
- Testing
- Laboratory Samples
- Where
- Puerto Rico
- Volunteers
- 250 people
- Sponsor
- Auxilio Mutuo Cancer Center
COVID-19, SARS-CoV-2
Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults
The aim of the study is to assess the safety, efficacy, and immunogenicity of AZD1222 for the prevention of COVID-19.
- Trial name
- NCT04516746
- Testing
- AZD1222
- Where
- 84 sites in United States, Chile and 1 more
- Volunteers
- 32,450 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Covid19
Physical Activity and the Risk of COVID-19 Infection and Mortality
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no cure for COVID-19, except for supportive treatments.
- Trial name
- NCT04631861
- Volunteers
- 132,069 people
- Sponsor
- Wonju Severance Christian Hospital
Stress, Anxiety
Cereset Research Long-Term Healthcare Worker Study
Randomized, controlled study of long-term maintenance Cereset Research after an initial 4-session intervention bolus versus usual care control following an initial 4-session intervention bolus.
- Conditions
- Stress, Anxiety, Autonomic Dysregulation, Acoustic Stimulation
- Trial name
- LT-HW (NCT05994261)
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
SARS-CoV-2
A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19
The mRNA-1273 vaccine is being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) infection.
- Trial name
- NCT04470427
- Testing
- mRNA-1273
- Where
- 100 sites in United States
- Volunteers
- 30,415 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19
A Multicentre Open-label Two-arm Randomised Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID19 (ATOMIC2)
A multi-centre open-label two-arm randomised superiority clinical trial of two weeks of oral Azithromycin 500mg once daily versus usual care in adult patients presenting to secondary care with clinically-diagnosed COVID-19 but…
- Trial name
- ATOMIC2 (NCT04381962)
- Testing
- Azithromycin Capsule
- Where
- 5 sites in United Kingdom
- Volunteers
- 298 people
- Sponsor
- University of Oxford
Pregnancy Related, COVID
Hydroxychloroquine Efficacy and Safety in Preventing SARS-CoV-2 Infection and COVID-19 Disease Severity During Pregnancy and Postpartum
It still unclear how SARS-CoV-2 affects pregnant women and their offspring, as well as which factors may influence obstetrical disease and outcomes, including the timing of maternal viral exposure by gestational age, the effects…
- Conditions
- Pregnancy Related, COVID, Covid-19
- Trial name
- COVID-Preg (NCT04410562)
- Testing
- Hydroxychloroquine
- Where
- 9 sites in Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Covid19
Changing of Trace Element, Homocysteine, Oxidative Stress Parameters and Physical Activity Levels in Covid-19
With the rapid spread of COVID-19 (SARS-CoV-2) disease all over the world and the announcement of a pandemic, researches on many different drug approaches have begun and these researches continue today.
- Trial name
- NCT04694703
- Testing
- Covid-19 group
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Izmir Bakircay University
COVID-19, SARS-CoV2 Infection
Asymptomatic and Pre-symptomatic Transmission of SARS-CoV-2 in a Community Congregant Setting
The overall aim of this study is to measure how transmission of COVID-19 occurs in communities - including the role of super spreaders and/or identifying conditions that may increase transmission risk, with a focus on congregant…
- Trial name
- NCT05145803
- Testing
- Polyvinylalcohol strip [diagnostic]
- Where
- 6 sites in United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Colorado School of Public Health
Sars-CoV2
Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19
No optimal antiviral intervention has been yet validated to treat COVID-19 disease. Comorbidities, such as older age, obesity, diabetes, history of cardiovascular diseases are associated with poor prognosis.
- Trial name
- HYdILIC (NCT04372082)
- Testing
- Standard of care (SOC), Hydroxychloroquine, Association of diltiazem and niclosamide
- Sponsor
- University Hospital, Lille
SARS CoV 2 Infection, COVID-19
Diagnosis of Respiratory Viruses in Children With Rhinoswab Junior
A study to investigate Rhinoswab as an alternative method to combined throat and deep nasal (CTDN) swab for respiratory sample collection in children who present to the Royal Children's Hospital (RCH) for viral testing.
- Trial name
- NCT05043623
- Testing
- Rhinoswab Junior, Combined nose and throat swab, Saliva swab
- Where
- Australia
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
COVID-19
Tocilizumab for Prevention of Respiratory Failure in Patients With Severe COVID-19 Infection
The purpose of this study is to find out whether the study drug tocilizumab is an effective treatment for COVID-19 infection.
- Trial name
- NCT04377659
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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