Clinical trials: Covid-19 Pneumonia
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
COVID-19
Chemoprophylaxis of SARS-CoV-2 Infection (COVID-19) in Exposed Healthcare Workers
Since December 2019, the emergence of a new coronavirus named SARS-Cov-2 in the city of Wuhan in China has been responsible for a major epidemic of respiratory infections, including severe pneumonia.
- Trial name
- COVIDAXIS (NCT04328285)
- Testing
- Hydroxychloroquine, Lopinavir and ritonavir
- Where
- 9 sites in France
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Covid19
Clinical Study to Evaluate the Effects of Disulfiram in Patients With Moderate COVID-19
This clinical trial evaluates the safety, efficacy, and biomarker levels of FDA-approved drug disulfiram in the treatment of adult subjects hospitalized with moderate COVID-19.
- Trial name
- NCT04594343
- Testing
- Disulfiram
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- ETICA
COVID-19
#StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
BACKGROUND Despite drastic quarantine measures, COVID-19 continues to propagate and threatens global healthcare systems by saturating their capacity with high transmissibility and the particularly protracted length of stay needed…
- Trial name
- #StayHome (NCT04385264)
- Testing
- Hydroxychloroquine, Mannitol
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Stroke, Mild Cognitive Impairment
Telerehabilitation of Balance Clinical and Economic Decision Support System
This study follows the successfully completed HOLOBalance project which was funded by the EU Horizon 2020 scheme. TheHOLOBalance platform delivers exercises demonstrated via a hologram of the physiotherapist and corrected in real…
- Conditions
- Stroke, Mild Cognitive Impairment, Vestibular Diseases, Long Covid19
- Trial name
- TeleRehab DSS (NCT06534164)
- Testing
- Full/High Tech Telerehabilitation decision support system, Basic/Low Tech Telerehabilitation decision support system, OTAGO Home exercise program
- Where
- 5 sites in Germany, Greece and 3 more
- Volunteers
- 460 people
- Sponsor
- University College, London
COVID-19
Socio-economic, Meteorological and Environmental Factors Associated With the Incidence of COVID-19
Socio-demographic factors in relation to the diagnosis of COVID cases are increasingly mentioned in the role of transmission, but unfortunately with a small number of conclusive publications on French data.
- Trial name
- NCT05379621
- Testing
- COVID-19 infection
- Where
- France
- Volunteers
- 28,377 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
COVID-19 Pandemic
Maternal and Fetal Outcomes in Pregnant Women With COVID -19,a Cross Sectional Study
The spread of a new coronavirus (SARS-CoV-2) from Wuhan, China, has been fast, and the World Health Organization (WHO) declared a pandemic on March 11th, 2020 .It has now spread worldwide and is one of the most severe public…
- Trial name
- NCT05608616
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
COVID19
Study of the Spread of COVID-19 in Saint Petersburg, Russia
Seroprevalence study of COVID-19 in Saint Petersburg, Russia is a regional longitudinal cohort study aiming to evaluate the spread dynamics of the COVID-19 disease in the population of Saint Petersburg.
- Trial name
- NCT04406038
- Where
- Russia
- Volunteers
- 1,038 people
- Sponsor
- European University at St. Petersburg
COVID-19
BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19
To evaluate the role of N terminal pro B type natriuretic peptide (NTproBNP), D-Dimer, and Troponin - I as risk factors in COVID-19 patients and to correlate these markers with in-hospital death in patients with COVID-19
- Trial name
- NCT04433026
- Testing
- N terminal pro B type natriuretic peptide (NTproBNP), D-Dimer, and serum Tropinin - I
- Volunteers
- 90 people
- Sponsor
- Assiut University
SARS-CoV-2 Infection, COVID-19
To Evaluate the Safety, Tolerability, Efficacy and Immunogenicity of BNT162b2 Boosting Strategies Against COVID-19 in Participants ≥12 Years of Age.
Substudy A: The study will evaluate the safety, tolerability, and efficacy of a booster dose of BNT162b2 when administered to participants having previously received 2 doses of BNT162b2 at least 6 months prior to randomization.
- Trial name
- NCT04955626
- Testing
- BNT162b2, BNT162b2 OMI, Combination BNT162b2 and BNT162b2 OMI
- Where
- 154 sites in United States, Brazil and 3 more
- Volunteers
- 16,372 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
COVID, Corona Virus Infection
Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia
CCAP is an investigator-initiated multicentre, randomized, double blinded, placebo-controlled trial, which aims to assess the safety and efficacy of treatment with convalescent plasma for patients with moderate-severe COVID-19.
- Conditions
- COVID, Corona Virus Infection, Viral Pneumonia
- Trial name
- CCAP (NCT04345289)
- Testing
- Convalescent anti-SARS-CoV-2 plasma
- Where
- 12 sites in Denmark
- Volunteers
- 147 people
- Sponsor
- Thomas Benfield
Infection Viral
COVID-19 Biological Samples Collection
The coronavirus disease 2019 (COVID-19) outbreak is now considered as a public health emergency of international concern by the World Health Organization.
- Trial name
- COLCOV19-BX (NCT04332016)
- Testing
- biological samples collection
- Where
- France
- Volunteers
- 615 people
- Sponsor
- University Hospital, Bordeaux
COVID-19 Pandemic, ICU
Chronic Pain in COVID-19 Patients Discharged From Intensive Care Unit
More than six million French were affected by SARS-COV2 epidemic. About 20% of infected peoples were hospitalized, and about 5% were admitted to the intensive care units (ICU) for severe SARS-COV2 acute respiratory distress…
- Conditions
- COVID-19 Pandemic, ICU, Pain, Chronic, Post Intensive Care Unit Syndrome
- Trial name
- NCT04940208
- Testing
- Pain and neuropsychological questionnaires, Quantitative Sensory testing
- Where
- 3 sites in France
- Volunteers
- 143 people
- Sponsor
- Mikhail Dziadzko, MD, PhD
COVID-19, Sars-CoV-2 Infection
Phase 3 Booster Vaccination Against COVID-19
The inactivated Booster Phase 3 study aims to determine the efficacy, safety, and immunogenicity of inactivated COVID-19 vaccines in subjects with a minimum of 90 days and a maximum of 270 days after the second dose of CoronaVac…
- Trial name
- NCT05077176
- Testing
- CoronaVac, Turkovac
- Where
- 41 sites in Turkey (Türkiye)
- Volunteers
- 4,340 people, healthy volunteers welcome
- Sponsor
- Health Institutes of Turkey
COVID-19 Infections
Monitoring the IgG/IgM Antibodies in COVID-19 Patients
The COVID-19 was declared a global pandemic by WHO more than a year ago, and the world is still experiencing a state of global emergency.
- Trial name
- NCT04810117
- Testing
- Serodiagnosis of IgG and IgM
- Where
- 2 sites in Pakistan
- Volunteers
- 373 people
- Sponsor
- University of Sargodha
Covid19
Diagnostic Performance of the ID Now™ COVID-19 Screening Test Versus Simplexa™ COVID-19 Direct Assay
Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), first appeared in China, and then spread around the world.
- Trial name
- COVID-IDNow (NCT04785898)
- Testing
- ID Now™ COVID-19 Screening Test
- Where
- France
- Volunteers
- 1,265 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Covid19, Coronavirus
Investigation of the Characteristics of Chronic Pain Developing After COVID-19
Data on pain after COVID-19 were generally collected from hospitalized patients and only include information on acute pain conditions. However, the characteristics of the chronic pain experienced after COVID-19 are unknown.
- Conditions
- Covid19, Coronavirus, Chronic Pain
- Trial name
- NCT04883216
- Where
- Turkey (Türkiye)
- Volunteers
- 776 people
- Sponsor
- Istanbul University
COVID-19
Phase I-II Trial of Dendritic Cell Vaccine to Prevent COVID-19 in Adults
This is an adaptive Phase I-II trial of a vaccine consisting of autologous dendritic cells previously loaded ex vivo with SARS-CoV-2 spike protein, with or without GM-CSF, to prevent COVID-19 in adults.
- Trial name
- NCT04386252
- Testing
- AV-COVID-19
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aivita Biomedical, Inc.
COVID-19
Effect of H2 Receptor Antagonist and Proton Pump Inhibitor on the Positivity Rates and Clinical Outcomes of COVID-19
This retrospective cohort study aims to evaluate the effect of proton pump inhibitor (PPI) or histamine-2 receptor antagonist (H2RA) on the clinical outcomes and positivity rates of Coronavirus Disease-19 (COVID-19).
- Trial name
- NCT04834752
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- South Korea
- Volunteers
- 400,000 people
- Sponsor
- Seoul National University Hospital
Coronavirus Infections, Pneumonia, Viral
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection
The scientific community is in search for novel therapies that can help to face the ongoing epidemics of novel Coronavirus (COVID-19) originated in China in December 2019.
- Conditions
- Coronavirus Infections, Pneumonia, Viral, Dyspnea
- Trial name
- NoCovid (NCT04290858)
- Testing
- Nitric Oxide
- Sponsor
- Xijing Hospital
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