Clinical trials: Covid19 Vaccination
Myocarditis, Myocarditis Acute
MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study
Myocarditis is inflammation of the heart muscle. Pericarditis is inflammation of the lining surrounding the heart muscle. Symptoms of these conditions can include pain in the chest and rapid or irregular heartbeat.
- Conditions
- Myocarditis, Myocarditis Acute, Pericarditis, Pericarditis Acute
- Trial name
- MYCOVACC (NCT06103123)
- Testing
- Stand of care ECG, Holter, MRI, ECHO, Quality of life questionnaire, Baseline Quality of Life questionnaire
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Cardiology Research UBC
SARS-CoV-2 Vaccination
Adaptive Immune Response to COVID-19 Vaccination
AICOVI (Adaptive Immune Response to COVID-19 Vaccination) is a prospective clinical cohort study aiming at studying the kinetics of vaccine-specific antibody production after COVID-19 vaccination in health care workers.
- Trial name
- AICOVI (NCT04826770)
- Testing
- BNT162b2, AZD 1222, mRNA-1273
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
SARS-CoV-2 Infection, Active Immunization
Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff
To investigate short- (3 and 8 weeks) and long-term (6, 9, 12, and 18 months) immune protection or response at the humoral and cellular levels before and after SARS-CoV-2 infection or vaccination in patients with moderately…
- Conditions
- SARS-CoV-2 Infection, Active Immunization, Immune Response, Immunosuppression
- Trial name
- DIA-Vacc (NCT04799808)
- Where
- Germany
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
COVID-19
The Phase Ⅱ/Ⅲ Trial of LYB001
The study will be conducted in two phases using a randomized, double-blind, placebo-controlled design. A phase II trial will be initiated to assess the safety of LYB001 as booster shots, and then proceed to a phase III trial to…
- Trial name
- NCT05602558
- Testing
- LYB001
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Yantai Patronus Biotech Co., Ltd.
Covid19
Neutralizing Antibody Level After COVID-19 Vaccination
1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2. investigate the factors on antibody titer.
- Trial name
- NCT05083026
- Testing
- COVID-19 neutralizing antibody
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Kyungpook National University Hospital
COVID-19
Mix and Match of the COVID-19 Vaccine for Safety and Immunogenicity
The main goals of this study are to assess the immune response and safety of two different vaccines for first, second, third and fourth doses as well as for differing intervals between the first and second dose of two-dose…
- Trial name
- MOSAIC (NCT04894435)
- Testing
- mRNA-1273 SARS-CoV-2 vaccine, BNT162b2, ChAdOx1-S [recombinant]
- Where
- 8 sites in Canada
- Volunteers
- 669 people, healthy volunteers welcome
- Sponsor
- Canadian Immunization Research Network
COVID-19
A Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cell, NVSI-06-09) and Inactivated COVID-19 Vaccine (Vero Cell)
A total of 516 healthy subjects aged 18 years and above who have been vaccinated with 2 doses/3 doses of inactivated COVID-19 vaccine, will be enrolled, and randomly assigned to experimental group and control group in a 1:1…
- Trial name
- NCT05293548
- Testing
- Recombinant COVID-19 Vaccine (CHO cell，NVSI-06-09), Inactivated COVID-19 vaccine (Vero cells)
- Where
- United Arab Emirates
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Vaccine Refusal
Clinic-based HPV and COVID-19 Vaccine Promoting Intervention for AfAm Adolescents in Alabama
In this 30-month study, the investigators propose to develop a culturally appropriate vaccine confidence intervention, targeting positive change related to HPV vaccine uptake behavior and reducing sentiments of hesitancy towards…
- Trial name
- NCT04604743
- Testing
- Intervention, TBN
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vaccine Hesitancy, COVID-19 Testing
A CHW Intervention to Identify and Decrease Barriers to COVID 19 Testing & Vaccination
The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and…
- Conditions
- Vaccine Hesitancy, COVID-19 Testing, Community Health Workers
- Trial name
- NCT05473936
- Testing
- Community Health Worker led curriculum
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
COVID-19
Immunogenicity and Safety of Fractional Booster Dose of COVID-19 Vaccines Available for Use in Pakistan/Brazil: A Phase 4 Dose-optimizing Trial
Since the emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen in late 2019, millions of people around the world have fallen ill and died from coronavirus disease 2019 (COVID-19), with…
- Trial name
- NCT05343871
- Testing
- Sinovac, AZD1222, BNT162b2
- Where
- 2 sites in Brazil, Pakistan
- Volunteers
- 2,354 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Vaccine Hesitancy, Climate Change
Messaging Strategies to Increase Peer Education on COVID-19 Vaccination and Climate Change
The primary objective of this protocol is to develop and evaluate peer communication interventions to encourage peer education around COVID-19 vaccination and climate change.
- Trial name
- NCT05530044
- Testing
- Social diffusion intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19
THEMBA II T-Cell Vaccine: Vaccination With saRNA COVID-19 Vaccines
This is a phase 1/2 open-label study assessing the safety, reactogenicity, and immunogenicity of saRNA COVID-19 boost vaccines in participants that have been previously vaccinated against or previously infected with COVID-19.
- Trial name
- NCT05370040
- Testing
- AAHI-SC2 Vaccine, AAHI-SC3 Vaccine, EUA or approved vaccine
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ImmunityBio, Inc.
COVID-19
Post Authorization Safety Profile of Booster IndoVac COVID-19 Vaccination
This study is Post Authorization Safety Study (PASS) Phase IV of Booster IndoVac COVID-19 Vaccination
- Trial name
- NCT06690502
- Where
- 28 sites in Indonesia
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Covid-19 Vaccination
The Effect of Covid-19 Vaccination in Patients Undergoing IVF
Since emerging in the last months of 2019, over 127 000 000 individuals have suffered severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and the documented death toll from coronavirus disease 2019 (COVID-19)…
- Trial name
- Covid-19 (NCT05063942)
- Volunteers
- 712 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
SARS CoV 2 Infection, COVID-19
I VACCIN Hospitalization of COVID-19 Patients
A REALLIFE evaluation of rate of hospitalized patients in Intensive Care Units and in medical Units of non -vaccinated patients vs vaccinated patients
- Trial name
- NCT05244343
- Where
- Tunisia
- Volunteers
- 1,096 people
- Sponsor
- Eshmoun Clinical Research Center
Vaccination Hesitancy, COVID-19
Using Text Messages to Boost COVID-19 Vaccine Booking Rate
This study is a nationwide randomised controlled trial (RCT) to test the impact of behavioural science-informed text messages notifying patients of their eligibility for the COVID-19 vaccine on vaccination rates.
- Trial name
- NCT05993260
- Testing
- Behavioural science-informed text messages, Control
- Where
- United Kingdom
- Volunteers
- 1,825,937 people, healthy volunteers welcome
- Sponsor
- The Behavioural Insights Team
Pregnancy
Observational Maternal COVID-19 Vaccination Study
This is a prospective, observational study. During the study, pregnant women will be followed post COVID-19 vaccination. Injection-site (local) and systemic reaction data will be assessed on vaccination day and during the 7 days…
- Trial name
- NCT04826640
- Testing
- Observational
- Where
- 4 sites in United States
- Volunteers
- 146 people
- Sponsor
- Duke University
Generation of Anti COVID-19 Antibodies in a Fetus, Whose Mother Was Exposed to COVID or Was Vaccinated During Pregnancy
COVID 19 ANTOBODIES IN PREGNANT WOMEN AND THEIR CONNECTION TO BETA CELL FUNCTION IN THE FETUS
The aim of this study is to check for the presence of COVID 19 antibodies [Covid-19, GAD-65, IA-2, ICA] in the blood of laboring women who have been exposed to either the virus itself or to the vaccine during pregnancy .
- Trial name
- NCT04860908
- Testing
- no intervention, observation only
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maaynei Hayesha Medical Center
Rheumatoid Arthritis, Spondyloarthritis
Vaccination Against SARS-Cov2 (COVID-19) in Chronic Inflammatory Rheumatism and Factors Determining Its Decision.
Rheumatoid arthritis and spondyloarthritis (ankylosing spondylitis and psoriatic arthritis mainly) are chronic inflammatory rheumatism (RIC), frequently onset in young adults. The prevalence is respectively 0.3 to 0.8% and 0.4%.
- Trial name
- VACCI-RIC (NCT04970550)
- Testing
- Non intervention
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hopital Nord Franche-Comte
COVID-19, Influenza
Effectiveness of An Influenza/COVID-19 Vaccine (mCombriax [mRNA-1083]) in Adults ≥ 65 Years
The purpose of this pragmatic randomized trials is to evaluate the comparative vaccine effectiveness (cVE) of mCombriax® (mRNA-1083) versus same day co-administration of the active comparators (i.e., high-dose influenza…
- Trial name
- DAN-COMBO (NCT07790523)
- Testing
- mCombriax® (mRNA-1083), Efluelda® (TIV-HD) and Spikevax® (mRNA-1273)
- Where
- 3 sites in Denmark, Spain
- Volunteers
- 410,000 people, healthy volunteers welcome
- Sponsor
- Tor Biering-Sørensen