Clinical trials: Covid19- Coronavirus- Sars-cov-2
Covid19
Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients
This double blind, randomized study is aiming to evaluate the efficacy of three doses (1gr/day) of methylpredisolone added to standard therapy in patients, with documented COVID-19 pneumonia, requiring hospitalization but not…
- Trial name
- NCT04673162
- Where
- 20 sites in Italy
- Volunteers
- 260 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Covid19, Corona Virus Infection
SPI-1005 Treatment in Moderate COVID-19 Patients
The study is a randomized, double-blind, placebo-controlled, dose escalation, multi-center clinical trial (RCT) of SPI-1005 in adult subjects with positive PCR test for novel SARS-CoV-2 (nCoV2) and moderate symptoms of COVID-19…
- Conditions
- Covid19, Corona Virus Infection, Coronavirus, Coronavirus Infection
- Trial name
- NCT04484025
- Testing
- Ebselen
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Aging, SARS-CoV-2 Infection
Impact of the COVID-19 Pandemic on the Health Status of People Aged 75 and Over and Their Caregivers
The measures to control the transmissibility of the Covid-19 pandemic have changed the daily routines of the population, increasing sedentary lifestyles, decreasing outdoor physical activity and limiting contact with neighbors…
- Conditions
- Aging, SARS-CoV-2 Infection, Caregivers, Frailty
- Trial name
- CUIDAMOS+75 (NCT05249868)
- Testing
- Exposure SARS-CoV-2 Infection
- Where
- 2 sites in Spain
- Volunteers
- 1,035 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
COVID-19 Pneumonia
Treatment of Coronavirus COVID-19 Pneumonia (Pathogen SARS-CoV-2) With Cryopreserved Allogeneic P_MMSCs and UC-MMSCs
Assessment of the clinical effects of infusions of cryopreserved allogeneic multipotent mesenchymal stem cells of the placenta and umbilical cord for COVID-19 patients with acute respiratory distress syndrome.
- Trial name
- NCT04461925
- Testing
- Placenta-Derived MMSCs; Cryopreserved Placenta-Derived Multipotent Mesenchymal Stromal Cells, Antibiotics, Hormones
- Where
- Ukraine
- Volunteers
- 30 people
- Sponsor
- Institute of Cell Therapy
COVID19
Evaluation of the AudibleHealth Dx AI/ML-Based Dx SaMD Using FCV-SDS in the Diagnosis of COVID-19 Illness
The AudibleHealth Dx is a diagnostic software as a medical device (Dx SaMD) consisting of an ensemble of software subroutines that interacts with a proprietary database of Signal Data Signatures (SDS), using Artificial…
- Trial name
- NCT05175690
- Testing
- Diagnostic Software as Medical Device
- Where
- United States
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- AudibleHealth AI, Inc.
Sars Cov 2
Outpatient Treatment With CoVid-19 With Prexablu
Within the epidemic context of phase 3 in Mexico, the implementation of new treatments that have been shown to be beneficial for patients in other countries is an urgent need.
- Trial name
- NCT04619290
- Testing
- Sublingual Methylene blue, Control patients
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Hospital Reg. Lic. Adolfo Lopez Mateos
Coronavirus
Factors Associated With a Positive SARS-CoV-2 Serology in Contact Subjects at High/Moderate Risk of Coronavirus SARS-CoV-2 Infection. COVID-19.
In December 2019, a pneumonia due to a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, in China. In a few weeks, the number of confirmed cases of SARS-CoV-2 infection has dramatically increased, with almost 150'000…
- Trial name
- NCT04322279
- Testing
- Serology, Sequencing
- Where
- 16 sites in France, French Guiana
- Volunteers
- 81 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Infection, COVID-19
COVID 19-Caregivers IGg Seroconversion
According to recent publications, the percentage of caregivers infected with COVID 19 is evaluated between 10 and 30% . This great variability is due, on the one hand to the intensity of the influx of covid plus patients and, on…
- Trial name
- CoSigS (NCT04353323)
- Testing
- Blood sampling
- Where
- France
- Sponsor
- University Hospital, Limoges
Anosmia, Asymptomatic COVID-19
Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19).
- Conditions
- Anosmia, Asymptomatic COVID-19, COVID-19 Respiratory Infection, Influenza
- Trial name
- NCT05040659
- Testing
- AROMHA Longitudinal Smell Test
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
COVID-19
Characterizing the Perioperative Epidemiology of SARS-CoV-2 (COVID-19) Spread for Quality Improvement of Perioperative Infection Control Program
In a case-series analysis, up to 20 patients undergoing elective or urgent/emergent surgery that are COVID-19 positive will be approached for patient consent.
- Trial name
- NCT04443803
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Randy Loftus
SARS-CoV-2, Vaccine
COVID-19 Vaccine Induced Adaptive Immune Responses
The coronavirus disease 2019 (COVID-19) caused by the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)，resulting in more than 82 million confirmed cases and caused around 1.8 million deaths, as of 2…
- Conditions
- SARS-CoV-2, Vaccine, COVID-19
- Trial name
- NCT04729374
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
COVID 19
Comparison of Cardiopulmonary Fitness Level With Normal Values After COVID-19
COVID-19 (Coronavirus disease 2019) is a new infectious disease caused by a virus named as SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2).
- Trial name
- NCT04753346
- Testing
- Physical Activity Level, Anxiety and Depression Assessment, Exercise Capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Ankara University
COVID-19, SARS-CoV-2 Infection
Novel Experimental COVID-19 Therapies Affecting Host Response
The overarching goal of the Master Protocol is to find effective strategies for inpatient management of patients with COVID-19. Therapeutic goals for patients hospitalized for COVID-19 include hastening recovery and preventing…
- Conditions
- COVID-19, SARS-CoV-2 Infection, Coronavirus Infection
- Trial name
- NECTAR (NCT04924660)
- Testing
- TXA127, TRV027, Fostamatinib
- Where
- 51 sites in United States
- Volunteers
- 1,060 people
- Sponsor
- Sean Collins
Covid19
SARS-CoV-2 IgG and IgM Serologic Assays
The primary objective is to assess and validate the ability of the Beckman Coulter Access COVID-19 IgG and IgM assays to detect immunity in COVID-19 patients in the Henry Ford Hospital Health System.
- Trial name
- NCT04562246
- Testing
- Serologic assays for antibodies to SARS-CoV-2
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Henry Ford Health System
Multiple Osteochondroma, Osteogenesis Imperfecta
Resilience and Coping in a Rare Skeletal Disease Population to Face Coronavirus (COVID-19) Outbreak Distress: a Longitudinal Study
In the COVID-19 outbreak context, people living with rare diseases have been highly troubled with anxiety, loneliness, and depression.
- Conditions
- Multiple Osteochondroma, Osteogenesis Imperfecta, Ollier Disease, Maffucci Syndrome
- Trial name
- RELOAD (NCT04844697)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
COVID19, Thrombosis
Prasugrel in Severe COVID-19 Pneumonia
Inflammatory diseases favour the onset of venous thromboembolic events in hospitalized patients. Thromboprophylaxis with a fixed dose of heparin/low molecular weight heparin (LMWH) is recommended if concomitant inflammatory…
- Trial name
- PARTISAN (NCT04445623)
- Testing
- Prasugrel Hydrochloride 10 MG Oral Tablet
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
COVID-19
Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older
The primary objectives of the study are: To assess the safety profile of the study vaccines in each study intervention group. To assess the neutralizing antibody profile after primary series vaccination in SARS-CoV-2-naïve…
- Trial name
- NCT04762680
- Testing
- SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 1, SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 2, SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 3
- Where
- 66 sites in United States, Australia and 5 more
- Volunteers
- 3,159 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Covid19, Pregnancy Related
Evaluation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19
Longitudinal prospective study in pregnant women withpositive serology or PCR for SARS-CoV-2 and indicationinvasive technique (amniocentesis or chorionic biopsy) that has the objective to evaluate the possible vertical…
- Trial name
- NCT04598347
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
SARS-CoV2 Infection
Novel SARS-CoV-2 Point-of-care Testing
The aim of the project is to study the feasibility of implementing a novel point-of-care test (POCT) for rapid detection of SARS-CoV-2 infection.
- Trial name
- NCT05034978
- Testing
- no intervention
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Olfactory Disorder
Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19)
The study will be a randomized controlled trial, involving patients with hyposmia/anosmia of onset immediately after an upper respiratory viral illness, assigned to three distinct study arms.
- Trial name
- NCT04374474
- Testing
- Olfactory retraining, corticosteroid nasal irrigation, smell household Items
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.