Clinical trials: Covid19- Coronavirus- Sars-cov-2
Pregnancy, Covid-19
Impact of COVID-19 Infection During Pregnancy on Newborns and Young Children
This study aim is to assess impact of COVID-19 infection during pregnancy on outcome of pregnancy, and on developement of the child in early life.
- Trial name
- ELIKYA COVID (NCT04432779)
- Testing
- no intervention
- Where
- Belgium
- Volunteers
- 1,362 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
COVID-19, Coronavirus Disease 2019
SARS-CoV-2 Nucleic Acid Detection Kit Clinical Performance Study
SARS-CoV-2 Nucleic Acid Detection Kit is an In Vitro Diagnostic (IVD) medical device intended for RNA detection of SARS-CoV-2 in human specimens using multiplex real-time polymerase chain reaction (RT-PCR) technology.
- Conditions
- COVID-19, Coronavirus Disease 2019, COVID-19 Pandemic, Diagnoses Disease
- Trial name
- CPS CW008 (NCT05492227)
- Testing
- Left-overs
- Where
- Spain
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- TransGen Biotech Co., LTD
Coronavirus
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2（COVID-19） Phase I Clinical Trial (3~17 Years Old)
Popular topic: Phase I clinical trial of recombinant new coronavirus vaccine (CHO cell) (3~17 years old) Research purpose:Main purpose:To evaluate the safety and tolerability of recombinant New Coronavirus vaccine (CHO cells) in…
- Trial name
- NCT04961359
- Testing
- Recombinant new coronavirus vaccine (CHO cell) group
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
COVID-19 Pandemic, Endocrine System Diseases
Hormonal Contributors to COVID-19 Infection (COV-ENDO)
The goal of this observational study is to measure the changes in the parameters of endocrine function and tissue sensitivity to hormones induced by SARs-CoV-2 infection.
- Trial name
- COV-ENDO (NCT05749770)
- Testing
- blood testing
- Where
- Italy
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
COVID-19 Pandemic
External Validation of Simplified 4C Mortality Score by Deleting CRP
The (Coronavirus Clinical Characterisation Consortoum) 4C mortality score is an accessible risk stratification score developed by the International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) based on…
- Trial name
- 4Cs (NCT06354946)
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Covid19, Bronchoscopy
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection
Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a…
- Conditions
- Covid19, Bronchoscopy, Narrow-band Imaging
- Trial name
- SARS-CoV2-NBI (NCT04884061)
- Testing
- NBI images and/or videos
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Covid19, SARS-CoV-2
Feasibility and Analytic Performance of TestNPass (IVDMD) for CoViD-19 Diagnosis on Saliva Sample
COVID19 pandemic and SARS-CoV-2 rapid progression worldwide are already historical landmarks of the 21st century owing to the magnitude of the event and the collective response that populations have adopted to face such threat.
- Trial name
- GraphealNpas (NCT04654442)
- Testing
- TestNPass
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Myeloma, Long COVID
Understanding Patterns of Fatigue in Health and Disease
Fatigue is a common symptom and can be the most distressing symptom of a range of medical conditions. This Ecological Momentary Assessment study will investigate lived experiences of fatigue in detail in individuals with myeloma…
- Conditions
- Myeloma, Long COVID, Heart Failure
- Trial name
- FATIGUE (NCT05622669)
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
SARS-CoV-2 Infection, COVID-19
Safety, Tolerability and Efficacy of Molnupiravir (EIDD-2801) to Eliminate Infectious Virus Detection in Persons With COVID-19
This was a phase IIa, double-blind, placebo-controlled, randomized trial, designed to compare the safety, tolerability, and antiviral activity of EIDD-2801 (molnupiravir) versus placebo as measured by SARS-CoV-2 viral RNA…
- Trial name
- NCT04405570
- Testing
- Molnupiravir 200 mg, Molnupiravir 400 mg, Molnupiravir 800 mg
- Where
- 10 sites in United States
- Volunteers
- 204 people
- Sponsor
- Ridgeback Biotherapeutics, LP
COVID-19
Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention
The purpose of the study is to assess safety and immunogenicity of heterologous booster vaccine containing combination of AZD1222 and rAd26-S (one of components of Gam-COVID-Vac vaccine) in adult subjects aged ≥ 18 years old to…
- Trial name
- NCT04686773
- Testing
- AZD1222, rAd26-S
- Where
- Azerbaijan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- R-Pharm
Ovarian Reserve, SARS-CoV-2 Infection
Effect of Sars-cov-2 on Donor Oocyte Quality and Quantity, a Multicenter Retrospective Study.
Purpose: To determine the impact of SARS-CoV-2 infection and immunization on ovarian response to controlled ovarian stimulation (COS) and embryo development after in vitro fertilization (IVF) Methods: A retrospective multicentric…
- Conditions
- Ovarian Reserve, SARS-CoV-2 Infection, Blastocyst
- Trial name
- NCT05562479
- Testing
- Sars Cov 2 infection, Sars Cov 2 vaccination
- Where
- Colombia
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Novafem
SARS-CoV-2 Infection, COVID-19
COVID-19 iCura SARS-CoV-2 Ag OTC: Clinical Evaluation
SARS-CoV-2 rapid antigen over the counter clinical performance evaluation.
- Trial name
- NCT05555030
- Testing
- iCura COVID-19 Antigen Rapid Home Test, RT-PCR Test
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New Day Diagnostics
COVID-19, ARDS
Respiratory and Hemodynamic Changes Induced in Mechanically Ventilated Patients for COVID-19
In the present context, it seems necessary to try to describe as precisely as possible the physiological alterations due to COVID-19.
- Conditions
- COVID-19, ARDS, Sars-CoV2
- Trial name
- PHYSIO-COVID (NCT04347928)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Lille
COVID19
Effectiveness of Hydroxychloroquine in Covid-19 Patients
To find the effectiveness of hydroxychloroquine alone and adjuvant with azithromycin in mild to severe Covide-19 pneumonia patients admitted to Coronavirus cell/ward of Ayub Teaching hospital, Abbottabad Pakistan.
- Trial name
- Covid (NCT04328272)
- Testing
- Hydroxychloroquine 200 Mg Oral Tablet, Azithromycin 500Mg Oral Tablet, Glucose tablets
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- Prof. Dr. Umar Farooq
COVID-19, Vaccine Reaction
Immunogenicity and Reactogenicity Following a Booster Dose of COVID-19 mRNA Vaccine (Pfizer-BioNtech) and Two Adjuvanted Sub-unit Vaccines (SP/GSK) Administered in Adults Who Received 2 Doses of Pfizer-BioNTech mRNA Vaccine as a Primary Vaccination
The vaccination campaign in France began in early 2021 and was declared mandatory for all French people in July 2021. The efficacy of COVID-19 vaccines has since been widely demonstrated, as well as their safety, and now 60% of…
- Trial name
- COVIBOOST (NCT05124171)
- Testing
- BNT162b2, CoV2 preS dTM adjuvanted vaccine (D614), Sanofi/GSK, CoV2 preS dTM adjuvanted vaccine (B.1.351), Sanofi/GSK
- Where
- France
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-COVID-19 Syndrome
Physical Functions and Lifestyle Behaviours in Post-COVID-19 Syndrome Based on Circadian Rhythms
Post-COVID-19 syndrome is associated with persistent symptoms such as fatigue, reduced physical activity, and impaired respiratory function.
- Trial name
- NCT07545499
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Birth, First, COVID-19
Online Childbirth Preparation Education in Covid-19 Pandemic
Today, pregnancy and childbirth are important life events that involve many difficulties and changes that must be overcome for both men and women.
- Conditions
- Birth, First, COVID-19, Fear of Childbirth
- Trial name
- NCT05115071
- Testing
- Childbirth preparation education
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Covid19, SARS-CoV-2
Changes in Cellular Immune Profile During COVID-19 Infection
Clinical specimens are collected from individuals either recovered from or with active SARS-CoV-2 infection to support process and analytical development for a potential cell-based immunotherapy in preclinical research…
- Trial name
- NCT04470999
- Testing
- Leukapheresis
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Serhat Gumrukcu, MD PhD
SARS-COV2, Severe Acute Respiratory Syndrome
Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2
The goal of this study is to evaluate if CT (Computerized Tomography) can effectively and accurately predict disease progression in patients with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Conditions
- SARS-COV2, Severe Acute Respiratory Syndrome, COVID-19
- Trial name
- NCT04320511
- Testing
- CT-V
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
SARS-CoV-2 Acute Respiratory Disease, Covid19
Pandemic Triage Score in Patients With Known or Suspected Severe Acute Respiratory Syndrome (SARS) CoronaVirus (CoV) 2 Infection
During this pandemic period, the goal of the health care system is to optimize the use of intensive care services for patients infected with SARS-CoV-2, given the frequency of complications that can lead to high mortality.
- Trial name
- STC-19 (NCT04371471)
- Testing
- STC-19 score
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
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