Clinical trials: Creatine
Exercise, Physical Performance
Examination of Certain Blood Parameters Following Performance and Acute Exercise at Specific Times of the Day
This study aims to investigate whether the time of day at which acute exercise is performed influences physical performance and acute hormonal and biochemical responses in healthy young male soccer players.
- Conditions
- Exercise, Physical Performance, Circadian Rhythm
- Trial name
- Acute & Blood (NCT07825740)
- Testing
- Standardized Acute Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Firat University
Muscle Weakness
Delivra Topical Creatine for Improving Muscular Power
Creatine is a nutritional supplement that is often ingested to improve exercise performance. The advent of a new product that is applied to the skin overlying muscle offers potential benefit, if the creatine can be targeted to…
- Trial name
- NCT02960425
- Testing
- Delivra TM Livsport preworkout cream
- Where
- 3 sites in Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Healthy
Creatine Timing on Resistance Training Adaptations in College Athletes
While the use of creatine monohydrate supplementation and its associated benefits are well researched and supported, the impact of the timing of when creatine is ingested is a highly nuanced topic.
- Trial name
- NCT05451498
- Testing
- Creatine, Maltodextrin
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Rocky Mountain University of Health Professions
Postmenopausal Women
Creatine on Bone Mass in Postmenopausal Women
Animal, in vitro and small-scale studies have suggested that creatine supplementation may augment bone mass. This clinical trial aims to investigate the effects of a 2-year creatine supplementation protocol on bone mass in…
- Trial name
- NCT01472393
- Testing
- Creatine supplementation
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cardiac Function and Hemodynamics
Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
The purpose of this study is to investigate the impact of creatine supplementation alone or in combination with a moderate session of physical activity on vascular reactivity and heart hemodynamics in elderly men.
- Trial name
- NCT05329480
- Testing
- Creatine Monohydrate, Maltodextrin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Radford University
Chronic Kidney Disease 5D
Intradialytic Exercise Combined With Creatine Monohydrate in Patients With Chronic Kidney Disease Undergoing Hemodialysis.
This study aims to evaluate the effects of creatine monohydrate supplementation and an intradialytic exercise program on body composition, biochemical parameters, and functional capacity in patients with chronic kidney disease…
- Trial name
- NCT07666815
- Testing
- Group A with creatine monohydrate, Group C Intradialytic Exercise Program, Comparison group D Hemodialysis
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
Healthy
Effects of Ischemic Preconditioning on Muscle Damage Induced by Excentric Exercise
Introduction: eccentric exercise (EE) has been widely used in rehabilitation and in improving physical fitness due to its mechanical advantage and less metabolic demand, however, EE can induce muscle damage providing structural…
- Trial name
- NCT04420819
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Paulista University
Healthy
High-resolution Phosphocreatine and Creatine Mapping of Human Muscle and Brain
In this study, we aim to develop and validate a noninvasive approach for quantifying and imaging energy metabolism, without contrast agents, on widely available clinical MRI scanners.
- Trial name
- NCT04234880
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Muscle Weakness
Delivra Topical Creatine Combined With Oral Creatine for Improving Muscular Power
Creatine is a nutritional supplement that is often ingested to improve exercise performance. The advent of a new product that is applied to the skin overlying muscle offers potential benefit, if the creatine can be targeted to…
- Trial name
- NCT03006861
- Testing
- 3.5 mL/d topical creatine, 21 g/d Oral creatine
- Where
- 3 sites in Canada
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Healthy, Deficiency Diseases
Creatine Kinase Levels and Clinical and Functional Parameters in Parajiu-jitsu Athletes
Introduction: Evidence indicates that muscle damage caused by exercise can lead to functional, biochemical and clinical damage. Therefore, it is pertinent to perform investigations related to the muscle damage marker, creatine…
- Trial name
- NCT03698578
- Testing
- combat fight
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Dihydrotestosterone, Testosterone
Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments
This study is a randomized, double-blind, placebo-controlled trial examining the effects of creatine monohydrate supplementation on androgens and hair loss in free-living adult males.
- Conditions
- Dihydrotestosterone, Testosterone, Hair Loss
- Trial name
- NCT04298840
- Testing
- Creatine Monohydrate Supplementation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University
Creatine Deficiency, X-linked, Creatine Deficiency Syndrome Due to Gamt Deficiency
Optical Imaging as a Tool for Monitoring Brain Function in Creatine Deficiency Syndromes
The objective of this project is to explore the potential of functional near-infrared spectroscopy (fNIRS) as innovative functional biomarker for clinical trial readiness in Creatine Deficiency Syndromes (CDS), a group of rare…
- Trial name
- NCT06292884
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Oxygen Deficiency
Creatine and GAA for Brain Oxygenation
The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of…
- Trial name
- CREGAA-OXY (NCT06371651)
- Testing
- Supplement
- Where
- Serbia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Creatine Absorption in Healthy Adults
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
The study aims to evaluate the novel OptiCreatine formulation, which combines creatine with other bioactive compounds purported to enhance absorption and reduce gastrointestinal (GI) discomfort.
- Trial name
- NCT07225335
- Testing
- OptiCreatine, Creatine Monohydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TSI Group LTD
Sarcopenia
Creatine Supplementation During GLP-1a Therapy
GLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of…
- Trial name
- NCT07625202
- Testing
- Dietary supplementation during a 12 week resistance-training program (creatine)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Muscle Development
Photobiomodulation On Muscle Recovery In Professional Soccer Players
Background: Photobiomodulation with low-level laser therapy (LLLT) has been widely used in clinical practice for diverse purposes, such as modulation of the inflammatory process, acceleration of the tissue repair process, pain…
- Trial name
- NCT03416998
- Testing
- phototherapy
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Depression
The Effect of Oral Bifidobacterium on Exogenous Creatine Absorption in Adult Subjects
The purpose of this clinical trial is to learn if Bifidobacterium has antidepressant-like effects by enhancing creatine absorption in adults.
- Trial name
- NCT06594406
- Testing
- Creatine, Bifidobacterium and creatine
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Strength, Muscle
Strategic Ingestion of Creatine Supplementation and Resistance Training in Trained Young Adults
Creatine supplementation improves measures of muscle accretion and performance compared to placebo during a resistance training program.
- Trial name
- NCT06438887
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Regina