Clinical trials: Creatine
Major Depressive Disorder
Creatine as a New Therapeutic Strategy in Depression
Creatine as a new therapeutic strategy in depression: A double-blind, parallel, randomized, add-on clinical trial of creatine versus placebo added to antidepressant treatment of patients with major depressive episode.
- Trial name
- NCT00313417
- Testing
- Creatine monohydrate
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Herzog Hospital
Frail Elderly Syndrome
Protein Intake and Resistance Training in Aging
Resistance training combined with protein or amino acids supplementation has been shown to be promising for mitigating age-related disabilities and comorbidities.
- Trial name
- NCT01890382
- Testing
- Whey protein, whey plus creatine, leucine supplementation
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Creatine Kinase, Muscular Diseases
Diagnoses Associated With Persistent Elevation of Creatine Kinase
Serum creatinine kinase (CK) level varies with age, gender, race and physical activity. For these reasons there is no normal serum CK level.
- Trial name
- NCT04838509
- Testing
- no intervention
- Where
- France
- Volunteers
- 148 people
- Sponsor
- Central Hospital, Nancy, France
Osteoarthritis, Knee
Creatine, Exercise and Inflammatory Markers in Knee Osteoarthritis
The goal of this research project is to determine the effectiveness of creatine supplementation and supported low-load walking exercise for managing systemic inflammatory biomarkers and joint symptoms in individuals diagnosed…
- Trial name
- NCT02290275
- Testing
- Creatine, Walking Exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Body Mass Index, Physical Exertion
Is The Level of Muscle Damage After The Drop Jump Protocol Affected By Body Weight and BMI?
This study investigated whether muscle damage induced by a drop jump protocol varies based on participants' body weight and BMI. Fifty healthy adults were divided into normal-weight and overweight groups.
- Conditions
- Body Mass Index, Physical Exertion, Muscle Damage, Creatine Kinase
- Trial name
- NCT07046598
- Testing
- Drop Jump Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Melike Nur Eroğlu
Supplement
Multi-ingredient Supplement for Strength and Power
It has been suggested that high amounts of total serum testosterone levels correlate with higher lean body mass, lowered fat mass, greater muscle strength, and faster recovery.
- Trial name
- NCT01971723
- Testing
- T+ Supplement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Florida State University
Juvenile Systemic Lupus Erythematosus, Juvenile Dermatomyositis
Creatine Supplementation in Pediatric Rheumatology
Creatine supplementation may improve strength, muscle mass, bone mass and muscle function in healthy and elderly people. The investigators speculate that creatine supplementation could have therapeutic effects in pediatric…
- Trial name
- NCT01217320
- Testing
- creatine
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Dietary Supplementation
Physiological Effects of Creatine Supplementation in Active Males
This study was designed to examine how different forms of creatine impact active males.
- Trial name
- NB4 (NCT03003988)
- Testing
- Creatine monohydrate, Creatine nitrate
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Creatine Absorption in Healthy Adults
Acute Pharmacokinetics of Create Wellness Gummies in Healthy Adults
The purpose of this study is to compare blood creatine levels following acute oral supplementation of Create Wellness creatine gummies to creatine monohydrate powder.
- Trial name
- NCT07579455
- Testing
- Create Wellness Creatine Gummies, Creatine Monohydrate Powder
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Diabetes, Renal Function
Creatine Supplementation and Diabetes
Creatine supplementation is capable of improving glucose tolerance in healthy subjects. The researchers aim to investigate whether this supplement can affect metabolic control in diabetic patients.
- Trial name
- NCT00992043
- Testing
- creatine, Exercise training
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Young Healthy Adults (no Medical Condition/Disease)
Creatine and Motor Skill Acquisition
The investigators will conduct a double-blind, placebo-controlled, repeated measures study of the effects of oral creatine monohydrate supplementation on motor skill acquisition and neurophysiology in young healthy adults.
- Trial name
- NCT05201651
- Testing
- Creatine Monohydrate
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Gastrointestinal Cancer, Gastrointestinal Neoplasms
A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer
This is a Phase 1 study currently evaluating PO administered ompenaclid in combination with FOLFIRI and bevacizumab in patients with advanced (i.e., locally advanced and unresectable, or metastatic) previously treated colorectal…
- Conditions
- Gastrointestinal Cancer, Gastrointestinal Neoplasms, Colorectal Cancer, Colorectal Neoplasms
- Trial name
- NCT03597581
- Testing
- ompenaclid, FOLFIRI, Bevacizumab
- Where
- 17 sites in United States
- Volunteers
- 89 people
- Sponsor
- Inspirna, Inc.
Iron-deficiency, Inflammation
Iron and Muscular Damage: FEmale Metabolism and Menstrual Cycle During Exercise
This project is an observational controlled randomized counterbalance study. One hundred and three physically active and healthy women were selected to participate in the IronFEMME Study, of which 57 were eumenorrheic, 30 were…
- Conditions
- Iron-deficiency, Inflammation, Exercise Induced Iron-deficiency, Exercise Induced Muscle Damage
- Trial name
- IronFEMME (NCT04458662)
- Testing
- Interval running protocol / eccentric-based resistance exercise protocol
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Exercise Recovery, Exercise-induced Muscle Damage
Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes
Athletes frequently perform high-intensity exercise to improve physical performance and aerobic capacity. However, such training can induce exercise-induced muscle damage, oxidative stress, and inflammatory responses that may…
- Conditions
- Exercise Recovery, Exercise-induced Muscle Damage, Oxidative Stress, Sports Performance
- Trial name
- CORD-RECOV (NCT07664345)
- Testing
- Pre-Exercise Cordyceps Sinensis, Post-Exercise Cordyceps Sinensis
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Local Anesthetic Complication, Local Anesthetic Drug Adverse Reaction
Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty
The aim of this study was to describe the postoperative "baseline" magnetic resonance imaging (MRI) appearance of the ipsilateral thigh musculature after total knee arthroplasty (TKA).
- Trial name
- NCT04821245
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Benaroya Research Institute
Congestive Heart Failure
Prospective Study on Prognosis of Cardiac Resynchronized Therapy (CRT), Implantable Cardioverter Defibrillator (ICD) Implantation in Patients With Congestive Heart Failure (CHF)
CRT and ICD has known as decreasing cardiac mortality in patient with heart failure. Especially, it has reported that CRT improved cardiac systolic function, quality of life of patients with heart failure.
- Trial name
- NCT02139449
- Testing
- ICD/CRT
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Breast Cancer, Breast Cancer Female
THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation
The study's purpose is to evaluate whether creatine supplementation can help breast cancer survivors respond quicker to exercise by improving strength, endurance, and body composition.
- Conditions
- Breast Cancer, Breast Cancer Female, Muscle Weakness
- Trial name
- THRIVE (NCT06395506)
- Testing
- Creatine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Huntington Disease, Sarcopenia
Creatine and Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation Plus Home-Based Exercise for Sarcopenia in Huntington's Disease
Huntington's disease (HD) is a rare neurodegenerative disorder in which accelerated loss of muscle mass, strength and autonomy (physical frailty and sarcopenia) contributes to functional decline.
- Conditions
- Huntington Disease, Sarcopenia, Frailty
- Trial name
- SARCO-HD (NCT07902206)
- Testing
- Creatine monohydrate, Beta-hydroxy-beta-methylbutyrate (HMB), Home-based multicomponent exercise program
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Universidad de Burgos
Alzheimer's Disease
Creatine to Augment Bioenergetics in Alzheimer's
By doing this study, researchers hope to see if creatine monohydrate is a helpful treatment for people with Alzheimer's disease.
- Trial name
- CABA (NCT05383833)
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center