Clinical trials: Creatine
Seizure, Syncope
Lactate Compared to Creatine Kinase as Diagnostic Marker in Generalized Epileptic Seizure
The investigators compared the feasibility of serum creatine kinase and serum lactate concentration as diagnostic markers to distinguish between generalized tonic-clonic seizures (GTCS) and syncopes in clinical settings that…
- Trial name
- NCT02926703
- Testing
- Serum lactate and CK concentrations in blood samples
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- RWTH Aachen University
Hyperlipidemia
Tolerability and Efficacy of Rosuvastatin - Fenofibrate Combine Therapy in Korean Patients With Combined Hyperlipidemia
Although the combination of statin and fenofibrate is one of the options for patients with combined hyperlipidemia, non-lipid effects of it has not been completely understood yet.
- Trial name
- NCT01414803
- Testing
- Lipid modification
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
Creatine Absorption in Healthy Adults
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
The study aims to evaluate the novel OptiCreatine formulation, which combines creatine with other bioactive compounds purported to enhance absorption and reduce gastrointestinal (GI) discomfort.
- Trial name
- NCT07225335
- Testing
- OptiCreatine, Creatine Monohydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TSI Group LTD
Huntington's Disease (HD)
Creatine Safety & Tolerability in Huntington's Disease
The purpose of this study is to extend findings from the creatine dose-finding study (CREST-UP1) in Huntington's disease to evaluate the long-term safety, tolerability, and clinical impact of high dose creatine.
- Trial name
- CREST-X (NCT01412151)
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Sarcopenia
Creatine Supplementation During GLP-1a Therapy
GLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of…
- Trial name
- NCT07625202
- Testing
- Dietary supplementation during a 12 week resistance-training program (creatine)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Muscle Development
Photobiomodulation On Muscle Recovery In Professional Soccer Players
Background: Photobiomodulation with low-level laser therapy (LLLT) has been widely used in clinical practice for diverse purposes, such as modulation of the inflammatory process, acceleration of the tissue repair process, pain…
- Trial name
- NCT03416998
- Testing
- phototherapy
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Depression
The Effect of Oral Bifidobacterium on Exogenous Creatine Absorption in Adult Subjects
The purpose of this clinical trial is to learn if Bifidobacterium has antidepressant-like effects by enhancing creatine absorption in adults.
- Trial name
- NCT06594406
- Testing
- Creatine, Bifidobacterium and creatine
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Background: Neurocognitive disorders affect how the brain uses oxygen. They may affect mental development in children. These disorders can be studied with imaging scans that use radiation; however, these methods are not ideal for…
- Conditions
- Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome, Creatine Transporter Deficiency, Niemann-Pick Disease Type C1
- Trial name
- NCT05642221
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Performance Enhancement
Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football Players
Creatine has been widely studies within the strength and conditioning background and has been seen to show positive effects on performance assess the effects of creatine on sports requiring a range of different fitness components…
- Trial name
- NCT07475676
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- St. Mary's University, Twickenham
Strength, Muscle
Strategic Ingestion of Creatine Supplementation and Resistance Training in Trained Young Adults
Creatine supplementation improves measures of muscle accretion and performance compared to placebo during a resistance training program.
- Trial name
- NCT06438887
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Regina
Heat Exposure, Exercise Performance
Effects of Creatine and Heat Exposure on Exercise Performance and Body Water Distribution
The goal of this clinical trial is to learn whether creatine supplementation changes how the body adapts to repeated exercise in the heat in healthy recreationally active adults and varsity athletes.
- Conditions
- Heat Exposure, Exercise Performance, Hydration, Body Fluid Compartments
- Trial name
- NCT07593014
- Testing
- Creatine Monohydrate
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Windsor
Facio-Scapulo-Humeral Dystrophy, FSHD2
Effect of Creatine Monohydrate on Functional Muscle Strength in Children With FSHD
This multi-centre, randomised, double-blind, placebo-controlled crossover trial will compare changes in strength-related motor function following treatment with creatine monohydrate to treatment with placebo, as measured by the…
- Conditions
- Facio-Scapulo-Humeral Dystrophy, FSHD2, FSHD1
- Trial name
- NCT02948244
- Testing
- Creatine Monohydrate
- Where
- Australia
- Volunteers
- 11 people
- Sponsor
- Murdoch Childrens Research Institute
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Physical Performance, Exercise Performance
The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and Cognition
The goal of this study is to learn if a new pre-workout supplement can improve exercise performance in healthy adults. It will also look at how the supplement affects mood and energy levels.
- Conditions
- Physical Performance, Exercise Performance, Endurance Exercise, Perceived Exertion
- Trial name
- NCT07225608
- Testing
- proprietary pre-workout supplement
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Cardiac Arrhythmia
SJM MRI Diagnostic Imaging Registry (IDE)
This study is a prospective, non-randomized, multi-center study of subjects implanted with an SJM pacemakers, implantable cardioverter defibrillator (ICD), and cardiac resynchronization therapy (CRT) devices who are clinically…
- Trial name
- NCT02807948
- Testing
- Pacemaker, ICD, or CRT device
- Where
- 58 sites in United States
- Volunteers
- 189 people
- Sponsor
- Abbott Medical Devices
Functionality, Cognition
Impact of Creatine Monohydrate Micronized Supplementation With or Without Multicomponent Training in Older Adults.
The goal of this clinical trial is to study and evaluate whether a protocol of creatine supplementation, with or without multicomponent training, improves functional and cognitive capacity in individuals over 75 years old.
- Conditions
- Functionality, Cognition, Strength Training Effects
- Trial name
- CREAGED (NCT06677359)
- Testing
- Creatine Group, Multicomponent Training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Safety of Short Term Creatine Hydrochloride Dosing
Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study
Background: Creatine monohydrate (typically 5-20 g/day) has a well-established safety profile across diverse populations. Creatine hydrochloride (CR-HCl) is a highly soluble creatine formulation that may allow effective…
- Trial name
- NCT07521059
- Testing
- creatine supplementation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Physical Inactivity
Blood Flow Restriction and Creatine Supplementation in Women
This research is examining the changes in muscle size, muscle function, body composition, strength, and blood vessel health. Specifically, the changes in these variables over the course of 8 weeks of training with or without…
- Trial name
- NCT05877417
- Testing
- Creatine Monohydrate, Blood Flow Restriction, Exercise
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Muscle Hypotrophy
Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men
This study is a 12-week randomized active control trial that is investigating the effects of Carnipure(R) AAS on muscle hypertrophy, body composition, and muscular strength adaptations in healthy men performing a resistance…
- Trial name
- NCT05681806
- Testing
- Carnipure AAS, Creatine Monohydrate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Elevated S-adenosylhomocysteine
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels
S-adenosylhomocysteine (SAH) is the end-product of methylation reactions in the body and the precursor to homocysteine. Elevated SAH in the blood is a reflection of the dysregulation of what is known as the S-adenosylmethionine…
- Trial name
- SAH (NCT05994794)
- Testing
- Alpha-GPC, Creatine and Ashwagandha (Sensoril®)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.