Clinical trials: Creatine
Head and Neck Cancer, Cancer Survivorship
Resistance Training and Creatine Supplementation for Head and Neck Cancer
The study will examine a 10-week resistance training program, with or without creatine monohydrate supplementation, in adult survivors of head and neck cancer.
- Conditions
- Head and Neck Cancer, Cancer Survivorship, Treatment-related Muscle Loss, Physical Function
- Trial name
- NCT07838090
- Testing
- Creatine Supplementation, Resistance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Muscle Loss
The Effect of Creatine on Muscle Loss
The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.
- Trial name
- CML (NCT01894737)
- Testing
- Creatine supplementation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Damage, Plyometric Exercises
Serum CPK and Creatinine Changes During Plyometric Training in Collegiate Athletes
This retrospective study evaluated the effects of an eight-week lower body plyometric training program on serum creatine phosphokinase (CPK) and creatinine levels in male collegiate volleyball players.
- Conditions
- Muscle Damage, Plyometric Exercises, Creatine Kinase, Exercise Physiology
- Trial name
- NCT07356193
- Testing
- Lower Body Plyometric Training, control group
- Where
- Saudi Arabia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Batterjee Medical College
Heart Failure, Congestive
Torsion Optimization to Reduce Symptoms and Improve Outcomes in Non-responders
Approximately 40% of resynchronization therapy recipients do not appear to clearly benefit. These patients are termed 'non-responders'.
- Trial name
- TORSION (NCT00867984)
- Testing
- Torsion optimized, Usual Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Fatigue, Metastatic Prostate Carcinoma
Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients
This trial studies how well resistance training with or without creatine monohydrate supplement works in improving body composition and health outcomes in patients with prostate cancer that has spread to other places in the body.
- Conditions
- Fatigue, Metastatic Prostate Carcinoma, Sedentary Lifestyle, Stage IV Prostate Cancer AJCC (American Joint Committee on Cancer) v8
- Trial name
- NCT03987217
- Testing
- Creatine Monohydrate, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Utah
Knee Osteoarthritis
Effects of Creatine Supplementation in Addition to Resistance Exercise Training in Patients With Knee Osteoarthritis
Despite the past decade being dedicated to bone and joint disease, the incidence and prevalence rates of osteoarthritis continues to rise, and till date not curative treatment has been identified for the management of knee…
- Trial name
- NCT04423887
- Testing
- Lower Extremity Resistance Exercise Training, Home Exercise Plan, Electrotherapy + Heating
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Renal Insufficiency
Effects of Creatine Supplementation on Renal Function
Creatine (CR) supplementation is commonly used by athletes. However, its effects on renal function remain controversial. The aim of this study was to evaluate the effects of creatine supplementation on renal function and…
- Trial name
- NCT00465140
- Testing
- creatine supplementation, aerobic exercise training
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Nutritional Status
A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population
This study will examine the impact of creatine supplementation on muscle function and cognitive performance in young and older subjects.
- Trial name
- NCT02058654
- Testing
- Creatine
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females
The investigators hypothesize that the administration of two widely available, naturally occurring dietary supplements, 5 hydroxytryptophan and creatine monohydrate, will reduce the severity of depression in individuals exposed…
- Trial name
- NCT02356107
- Testing
- 5-hydroxytryptophan and Creatine monohydrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Amyotrophic Lateral Sclerosis
Creatine for the Treatment of Amyotrophic Lateral Sclerosis
Creatine is a naturally occurring chemical involved in the production of energy in muscle. Abnormalities in creatine have been linked to the progression of degenerative neuromuscular diseases such as amyotrophic lateral sclerosis…
- Trial name
- NCT00070993
- Testing
- creatine monohydrate
- Where
- 6 sites in United States
- Volunteers
- 110 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acute Coronary Syndrome, Myocardial Infarction
Quantification and Description of the Increase in Serum Troponin Following Acute Coronary Syndrome
The new assay of troponins T (highly sensitive troponins) detects concentrations much lower than before. Few data are currently available on their kinetics during acute coronary syndrome, especially in regard to the correlation…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina
- Trial name
- QUANTUM (NCT01698021)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Université de Sherbrooke
Cognitive Function Assessment, Mental Fatigue
Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults
This study examined whether short-term creatine supplementation affects cognitive function in healthy young adults. Participants were randomly assigned to take either creatine monohydrate or a placebo for 10 days.
- Trial name
- NCT07867041
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Metastatic Prostate Cancer
Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
The goal of this clinical trial is to test the use of creatine monohydrate supplementation with resistance training to preserve muscle mass and help lessen prostate cancer progression.
- Trial name
- CREATINE-52 (NCT06112990)
- Testing
- creatine monohydrate, Home-based, telehealth
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Healthy Men Doing Resistance Training
Effects of Soy Protein and Creatine Supplementation on Certain Parameters in Men Performing Resistance Exercise
The study will consist of a total of four visits. On the day of the first visit, participants who volunteer to take part in the study will be informed about the research, informed consent forms will be completed, and forms for…
- Trial name
- NCT07735988
- Testing
- soy protein, Creatine Monohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yakup Enes Çam
Juvenile Dermatomyositis
The Effect of Creatine Supplementation on Muscle Function in Childhood Myositis
This project will bring together a multidisciplinary team of pediatric rheumatologists, neurologists, metabolic geneticists and exercise physiologists to determine the effect of creatine (CR) supplementation on muscle function…
- Trial name
- NCT02267005
- Testing
- Creapure, Glucose Tablet
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- The Hospital for Sick Children
Mitochondrial Disease
Magnetic Resonance Imaging (MRI) Muscle Phenotyping in Mitochondrial Disease
The purpose of the study is to use a new research imaging technique, a kind of magnetic resonance imaging (MRI), to measure important metabolic features of muscle, including mitochondrial function, in people with mitochondrial…
- Trial name
- NCT02154711
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy
Interval Training Plus Creatine Effects on Performance and Glucose Tolerance
Recent evidence suggests that high -intensity interval training (HIIT) may be an effective strategy to improve cardiorespiratory fitness, exercise performance, and insulin sensitivity.
- Trial name
- Cr + HIIT (NCT02370212)
- Testing
- Creatine, High intensity interval training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults
This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT07756658
- Testing
- Tyrosol, Creatine Monohydrate, Resistant Dextrin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Depression, Dual Diagnosis
Open-Label Creatine Study for Female Meth Users
Study Purposes and Objectives: The objectives should be stated in such a way that the reader can determine the appropriateness of the study design. If appropriate, state the specific hypotheses being tested and/or study aims.
- Conditions
- Depression, Dual Diagnosis, Substance Use
- Trial name
- NCT02189915
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw