Clinical trials: Critical Care, Intensive Care
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Stress, Psychological, Emergency Medicine, Transport
Benefit of the FLYing Transport of Patients Requiring Mobile Intensive Care Unit
Patient care who requires fast and intensive care by a mobile intensive care unit in a rescue helicopter is a common practice in Auvergne since more than 3 years.
- Conditions
- Stress, Psychological, Emergency Medicine, Transport, Critical Care
- Trial name
- FLY-MICU (NCT04578054)
- Testing
- Flying transport
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Critical Thinking
Distance Education for Nursing Students on Critical Thinking
Critical thinking forms the basis of nursing knowledge. Critical thinking skills constitute a vital part of the nurse's work performance, adaptation, problem solving, awareness of the responsibilities of the profession, and the…
- Trial name
- NCT05403411
- Testing
- Distance education for nursing students on critical thinking
- Where
- Turkey (Türkiye)
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Esra Tayaz
Malnutrition, Critical Illness
Anabolic Steroids for Nutritional Rehabilitation of Critically Ill Patients
This prospective, double-blinded study will determine the feasibility of determining the efficacy of a weekly intramuscular injection of nandrolone (an anabolic steroid) in malnourished ICU patients.The data from this study will…
- Trial name
- NCT00242463
- Testing
- Nandrolone (anabolic steroid)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sepsis, Acute Lung Injury(ALI)
Recovery of Physical Function After Critical Illness In Older Adults
The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially.
- Trial name
- RETURN (NCT07225257)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Post-Intensive Care Recovery
A Recovery-Oriented Counselling Group
The purpose of this study is to evaluate a recovery-oriented group counselling program for post-discharged critical illness survivors and their caregivers.
- Trial name
- NCT03925181
- Testing
- Counselling Group
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Intellectual Disability, Perceptual Disorders
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
The purpose of this study is to determine the relationships between sedative exposure during pediatric critical illness and long-term neurocognitive outcomes.
- Conditions
- Intellectual Disability, Perceptual Disorders, Memory Disorders
- Trial name
- RESTORE-cog (NCT02225041)
- Where
- 31 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Interprofessional Relations, Interprofessional Education
Interprofessional Collaboration in the Cardiac Intensive Care Unit (CICU): An Action-Research Training Project
This study evaluates the impact of a structured interprofessional training program on daily collaboration within the Cardiac Intensive Care Unit (CICU/UTIC) at the University Hospital of Parma.
- Conditions
- Interprofessional Relations, Interprofessional Education, Attitude of Health Personnel, Intensive Care Units
- Trial name
- COLLUTIC_25 (NCT07360366)
- Testing
- The training phase of the project consists of an interactive course aimed at healthcare professionals (physicians, nurses and OSS) to improve their ability to recognise and enact effective collaborati
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Critical Illness
ICU Fluid Utilization Survey in Southeast Asia
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume…
- Trial name
- Fluid-SEA (NCT06034990)
- Testing
- 10-min online survey
- Where
- Thailand
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Critical Care
Montreal Toulouse Test With Eye Tracking in Intensive Care Unit to Evaluate Comprehension
Assessment of the level of oral comprehension of the intensive care patient is essential to improve their care because they have often troubles like delirium.
- Trial name
- MEXICO (NCT05078632)
- Testing
- Montreal-Toulouse Test adapted in eye tracking
- Where
- France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Anxiety, Depression
Improving Patient and Family Centered Care in Advanced Critical Illness
One in five deaths in the U.S. occurs in or shortly after discharge from an intensive care unit (ICU), typically following decisions made by surrogate decision makers to forego life prolonging treatment.
- Trial name
- PARTNER (NCT01844492)
- Testing
- The PARTNER Intervention, ICU Usual Care Control
- Where
- United States
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Muscle Wasting in Critically Ill
Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients
Acute skeletal muscle wasting in ICU patients is associated with functional impairment and with increased risk of death. Of what we know today, physical disability can persist up to 5 years.
- Trial name
- ProBoNo (NCT03587870)
- Testing
- Enteral nutrition with Fresubin Intensive
- Where
- Switzerland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Nursing Caries, Satisfaction
In-Situ Simulation Different Debriefing Methods
The goal of this pre-test-post-test randomized controlled experimental study is to examined the effects of the learning conversation (LC)-based, 3D model-based, and standard debriefing methods on critical thinking, debriefing…
- Conditions
- Nursing Caries, Satisfaction, Simulation of Physical Illness
- Trial name
- NCT06052007
- Testing
- LC-Based Debriefing, 3D Model-Based Debriefing
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Sedated ICU Patients
IMPROVE Critical Care Study (Pilot)
The Pilot Clinical Investigation planned is a prospective, unblinded randomized pilot trial comparing sedation management using a protocol based on responsiveness with standard sedation management.
- Trial name
- NCT01361230
- Testing
- "Sedation Trial Monitor" is the name of the device used.
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Covid-19
Recovery After Critical Covid-19 Infection
The study focuses on the recovery of respiratory, cardiovascular and neurological/neuropsychological recovery after intensive care treatment for covid-19.
- Trial name
- RECOVID (NCT04864938)
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Sedation
Impact of a Nurse Implemented Sedation and Analgesia Algorithm in Surgical Intensive Care Unit
To show that the nurse implementation of a sedation and analgesia algorithm is beneficial to the patient in terms of sedative drugs reduction and thus overall decrease in duration of mechanical ventilation and the morbidity and…
- Trial name
- ALGOSEDA (NCT03186521)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Nurse's Role, Anxiety
Investigation of the Effect of Virtual Reality Software on Nurses' Clinical Practice, Problem Solving and Clinical Decision Making Skills and Anxiety in the Care Management of Intensive Care Patients.
In the light of technological developments, learner-centered methods have begun to replace traditional teaching methods. Simulation applications are increasing in order to ensure patient safety and improve the quality of care in…
- Conditions
- Nurse's Role, Anxiety, Nursing Caries
- Trial name
- NCT05982288
- Testing
- Virtual Reality Software
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University