Clinical trials: Critical Care
Intensive Care Unit, Critical Care
Effects of Nonpharmacological Interventions in Sleep Quality, Anxiety, and Delirium for Patients of Adult Intensive Care Units
This study will investigate the effect of nonpharmacological intervention in sleep quality, anxiety and delirium among adult ICU patients.
- Conditions
- Intensive Care Unit, Critical Care, Sleep Quality, Anxiety
- Trial name
- Sleep (NCT06774599)
- Testing
- music combined with lavender essential oil group
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pain Management
Nurse-led Pain Management in Adult ICU
This project is about implementing a pain scale, the Critical Care Pain Observation Tool (CPOT), in ICU settings at King Abdullah Medical City to evaluate its impact on nurse pain assessment and management.
- Trial name
- NCT05488834
- Testing
- Critical-Care Pain Observation Tool
- Where
- Saudi Arabia
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Safety
Intensive Care Nurses' Training Package on the Safety Culture of Geriatric Patients
This study aims to determine the effect of intensive care nurses' training package on the safety culture of critically ill geriatric patients.
- Trial name
- NCT05910918
- Testing
- Intensive Care Nurses' Training Package
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
İntensive Care, Nursing
The Effect of Reiki on Pain, Anxiety and Haemodynamic Parameters in Patients Receiving Mechanical Ventilator Support
Patients receiving mechanical ventilation (MV) support in intensive care units (ICU) may have some negative experiences. The most common of these are problems such as pain, agitation, anxiety, deterioration in comfort, dry mouth…
- Conditions
- İntensive Care, Nursing, Reiki
- Trial name
- NCT06526949
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Acute Respiratory Failure, Mechanical Ventilation
A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication
- Trial name
- TIME (NCT06042621)
- Where
- 5 sites in United States
- Volunteers
- 7,818 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Critical Illness
SC2i Tissue and Data Repository Protocol
The purpose of this study is to collect samples of blood, urine, cerebrospinal fluid (CSF, the fluid that surrounds the brain and spinal cord), wound tissue and/or wound fluids, and other body fluids and tissues from people who…
- Trial name
- SC2i (NCT02182180)
- Where
- 4 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Electroencephalogram, Intensive Care Units
Critical Care EEG Course
Knowledge of the basic fundamental skills of electroencephalography would enable medical and nursing staffs to provide efficient and effective bedside EEG monitoring in critically ill patients.
- Conditions
- Electroencephalogram, Intensive Care Units, Teaching Intervention
- Trial name
- NCT03545776
- Testing
- Critical Care EEG Course
- Where
- 6 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ictal Group
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Advance Care Planning, End of Life Care
Advance Care Planning for Critical Care - A Prelude to Breaking Barriers
Advance Care Planning (ACP) is a process of 'reflection and communication, in which a person with decision-making capacity makes decisions regarding their future health and/or personal care in the event that they become incapable…
- Trial name
- NCT02797444
- Testing
- semi-structured interviews
- Where
- 2 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sedation
Impact of a Nurse Implemented Sedation and Analgesia Algorithm in Surgical Intensive Care Unit
To show that the nurse implementation of a sedation and analgesia algorithm is beneficial to the patient in terms of sedative drugs reduction and thus overall decrease in duration of mechanical ventilation and the morbidity and…
- Trial name
- ALGOSEDA (NCT03186521)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Sepsis, ARDS
Early Severe Illness TrAnslational BioLogy InformaticS in Humans
Advanced stages of the response to life-threatening infection, severe trauma, or other physiological insults often lead to exhaustion of the homeostatic mechanisms that sustain normal blood pressure and oxygenation.
- Conditions
- Sepsis, ARDS, Critical Illness, Neurocognitive Dysfunction
- Trial name
- ESTABLISH (NCT05591924)
- Testing
- Phelebotomy, Broncheoalveolar Lavage, Tracheal Aspirate
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Missed Nursing Care, Patient Safety
Perioperative Nursing Workload, Missed Care, and Near-Miss Events
This prospective, single-center observational study examines the relationship between perioperative nursing workload and safety-critical perioperative nursing care in the operating rooms of Agri Training and Research Hospital.
- Conditions
- Missed Nursing Care, Patient Safety, Workload
- Trial name
- NCT07834580
- Testing
- Structured Direct Observation and Workload Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Hemodynamic Assessment, Bedside Ultrasonography
Assessment of LVOT VTI in Healthy Volunteers
Healthy subjects will have transthoracic echocardiography evaluation of Left Ventricular Outflow Tract Velocity-Time Integral (LVOT VTI) performed by operators after brief training.
- Conditions
- Hemodynamic Assessment, Bedside Ultrasonography, Point of Care Ultrasound (POCUS)
- Trial name
- NCT07600931
- Testing
- transthoracic echocardiography
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Critical Illness, Delirium in the Intensive Care Unit
Pilot Feasibility Study of a Pragmatic Mixed-Methods Randomized Controlled Trial on a Follow-Up Bundle of Care for ICU Survivors and Caregivers
~80% of ICU survivors experience profound long-term cognitive, physical, and psychiatric impairments known as post-intensive care syndrome (PICS).
- Trial name
- IMPACT-ICU (NCT06681649)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cardiopulmonary Arrest, Nurse's Role
Mobile Micro-learning on Nurses' Self-confidence, Motivation, and Stress
Before and after effect of using mobile micro-learning on their self-confidence, motivation, and stress toward cardiopulmonary resuscitation.
- Trial name
- NCT06693232
- Testing
- Mobile micro-learning
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Damanhour University