Clinical trials: Cutaneous Abscess
Skin Abscess
Comparison of Loop and Primary Incision&Drainage Techniques in the Emergency Department
Skin abscesses are among the most common soft tissue infections cause emergency room visits frequently. Management of abscess drainage and prevent further complications are important entities for emergency physicians.
- Trial name
- NCT02286479
- Testing
- Incision and Drainage, Loop drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kocaeli University
Abscess
The LOOP Trial in Treatment of Skin Abscesses
This prospective, randomized controlled trial enrolled a convenience sample of adults and children presenting to two Level 1 trauma centers over 12-months with subcutaneous skin abscesses necessitating drainage.
- Trial name
- NCT03398746
- Testing
- LOOP Technique, Standard incision and drainage
- Volunteers
- 217 people
- Sponsor
- Orlando Regional Medical Center
Furunculosis
Safety and Tolerability Study of Antimicrobial TheraGauze for Skin Abscess
The goal of this study is to demonstrate safety and tolerability of a novel antimicrobial wound dressing, Antimicrobial TheraGauze.
- Trial name
- NCT02334384
- Testing
- Antimicrobial TheraGauze
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Eastern Virginia Medical School
Cutaneous Abscess, Pain
Injectable Lidocaine Versus Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses
Local anesthesia used for incision and drainage of abscesses is known to be painful. We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I\&D) of skin…
- Trial name
- NCT02066818
- Testing
- Lidocaine/tetracaine patch, 1% lidocaine
- Volunteers
- 20 people
- Sponsor
- East Carolina University
Cutaneous Abscess
Trial of Abscess Drainage Techniques
Comparing the outcome of traditional incision and drainage with a larger skin incision with or without gauze packing of cutaneous abscess in pediatrics versus a new minimally invasive incision and drainage with two small…
- Trial name
- NCT02545946
- Testing
- vessel loop, traditional I&D with or without packing
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Metastatic Breast Cancer, Leptomeningeal Disease
Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis
This study is a prospective evaluation of systemic, intravenous high-dose methotrexate (HD-MTX, 8 g/m2) in patients with triple negative, HER2-positive, and hormone refractory breast cancer with leptomeningeal metastasis (LMD)…
- Trial name
- NCT02422641
- Testing
- High-dose Methotrexate (8 gm/m2; HD-MTX)
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Major Cutaneous Abscess, Cellulitis
A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA Study
Characterization of the safety profile of TR-701 Free Acid (FA) in patients with major cutaneous abscess or cellulitis/erysipelas.
- Conditions
- Major Cutaneous Abscess, Cellulitis, Erysipelas
- Trial name
- NCT01519778
- Testing
- TR701 FA
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Cutanoeus Abscesses
Comparison of Suturing and Packing of Drained Abscesses
The standard treatment for skin abscesses in drainage followed by packing to prevent premature closure and reaccumulation of pus.
- Trial name
- NCT00465049
- Testing
- PRIMARY CLOSRE, SECONDARY CLOSURE, SPONTANEOUS HALING
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stony Brook University
Skin Disease, Bacterial, Abscess
Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage
The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been…
- Trial name
- NCT02024867
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Lucy Holmes, MD
Abscess
Comparison of Ultrasound-Guided Needle Aspiration and Open Incision and Drainage for Cutaneous Abscesses
The investigators propose to conduct a, two armed, randomized, controlled pilot study to assess the clinical effects of a) open incision, drainage with daily packing changes, compared to b) Ultrasound guided needle aspiration, in…
- Trial name
- NCT01186900
- Testing
- ultrasound-guided needle aspiration
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Ottawa Hospital Research Institute
Abscess of Skin and/or Subcutaneous Tissue
Loop Drainage: Effectiveness in Treating Cutaneous Abscesses
In the Emergency Department (ED), patients frequently seek medical treatment for cutaneous abscesses. Traditional incision and drainage (I\&D), with or without packing of cutaneous abscesses has long been the accepted standard of…
- Trial name
- NCT02697279
- Testing
- Traditional Incision and Drainage., Loop drainage
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Maryland, Baltimore
Cutaneous Abscess
Irrigation Versus no Irrigation for Cutaneous Abscess
In this study, the investigators are trying to find out if washing out the abscess (pocket of pus) with fluid will help, instead of only taking out the pus.
- Trial name
- NCT01606657
- Testing
- Irrigation, No Irrigation
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of California, San Francisco
MRSA
Community-Assoc. S. Aureus Colonization and Recurrent Infection in Pts With Uncomplicated S. Aureus Skin Abscesses
Infections due to S. aureus are a major healthcare burden. Currently there is not an effective way to prevent S. aureus infection.
- Trial name
- CIRCUS (NCT02690415)
- Testing
- Antibiotics Given, Antibiotics not given
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Southern Illinois University
Pneumonia, Pleural Effusion
Evaluation of Ultra-portable Ultrasound in General Practice
This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months.
- Conditions
- Pneumonia, Pleural Effusion, Renal Colic, Hepatic Colic or Cholecystitis
- Trial name
- EPEMedG (NCT04127149)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 166 people
- Sponsor
- Hospices Civils de Lyon
Uncomplicated Cutaneous Abscess
A Randomized Blinded Trial of Abscess Management With Packing vs No Packing
Adult patients presenting to the emergency department with superficial cutaneous abscesses will be randomized after incision and drainage to standard care with wound packing or no packing to determine if there is a difference in…
- Trial name
- NCT01698996
- Testing
- Packing vs No Packing
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Abscess of Skin and/or Subcutaneous Tissue
Loop Drainage Versus Incision and Drainage for Abscesses
This is a multicenter randomized controlled trial of loop drainage versus traditional incision and drainage in adult patients presenting to the emergency department.
- Trial name
- NCT03911518
- Testing
- Loop drainage, Incision and drainage
- Sponsor
- Gary Peksa
Abscess
Trial of Antibiotic Treatment for Skin Abscess in Patients at Risk for Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
Patients will be enrolled in a multi-center study to prospectively evaluate outcome after treatment for an uncomplicated skin abscess. All patients will receive incision and drainage and wound cultures.
- Trial name
- NCT00829686
- Testing
- Septra
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Skin and Subcutaneous Tissue Bacterial Infections, Wound Infection
A Study of Safety, Tolerability, and Efficacy of AFN-12520000 in the Treatment of Acute Bacterial Skin and Skin Structure Infections Due to Staphylococci
The purpose of the study is to determine the safety, tolerability and effectiveness of AFN-12520000 for in the treatment of Staphylococcal infections of the skin.
- Conditions
- Skin and Subcutaneous Tissue Bacterial Infections, Wound Infection, Cutaneous Abscess, Burn Infection
- Trial name
- NCT01519492
- Testing
- AFN-12520000
- Where
- 14 sites in United States, Canada
- Volunteers
- 103 people
- Sponsor
- Affinium Pharmaceuticals, Ltd
Cutaneous Abscess
Antimicrobial Stewardship Through MRSA Diagnosis in Emergency Department (ED) Patients With Abscesses
This study expands upon pilot data for feasibility since May 2011. The study aims to evaluate the effect of rapid test availability on use of targeted spectrum antibiotics for non-MRSA abscesses in ambulatory patients in the…
- Trial name
- NCT01523899
- Testing
- Xpert MRSA/SA SSTI, Standard culture
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- George Washington University
Cutaneous Abscess
Derma-Stent Novel Abscess Packing Device
In this research study, a device called the Derma-Stent will be tested. The sponsor of the study, Mar-Med Company, will supply the device.
- Trial name
- NCT03171714
- Testing
- Derma-Stent, Usual care, cotton gauze packing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Aaron Brody, MD, MPH