Clinical trials: Cystoid Macular Edema Following Cataract Surgery
Cystoid Macular Edema, Diabetes Mellitus
Assessing Diabetes Mellitus on Cytokine Analysis and Macular Edema Following FLACS
The purpose of this study is to assess the effects of diabetes mellitus (DM) on anterior chamber cytokine production and postoperative macular edema in patients undergoing femtosecond laser-assisted cataract surgery (FLACS).
- Conditions
- Cystoid Macular Edema, Diabetes Mellitus, Cataract
- Trial name
- NCT04856670
- Testing
- Cataract surgery
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Macular Edema, Epiretinal Membrane
Epiretinal Membrane and Pseudophakic Cystoid Macular Edema
Prospective, observational cohort study evaluating the association between pre-surgical existence of an epiretinal membrane (ERM) and the development of pseudophakic cystoid macular edema (PCME) using spectral domain optical…
- Trial name
- NCT02693353
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Loma Linda University
Cystoid Macular Edema Following Cataract Surgery, Bilateral
Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery
The purpose of this study is to compare effects of preoperative and postoperative use of topical ketorolac tromethamine 0.4% versus placebo in uncomplicated cataract surgery.
- Trial name
- NCT01542190
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Cystoid Macular Edema Following Cataract Surgery, Vitreous Hyperreflective Dots
Vitreous Hyper Reflective Dots in Association With Pseudophakic Cystoid Macular Edema
The aim of this study is to assess the association between vitreous hyper-reflective dots (VHD) and the macular thickness changes following uneventful phacoemulsification.
- Trial name
- NCT05811182
- Where
- Austria
- Volunteers
- 97 people
- Sponsor
- Medical University of Graz
Cataract, Cystoid Macular Edema After Phacoemulsification
Effects of Bromfenac on Macular Thickness After Phacoemulsification Surgery
The goal of this clinical trial is to learn if bromfenac ophthalmic solution can prevent cystoid macular edema (CME) and reduce macular thickness in patients undergoing phacoemulsification surgery for cataract removal.
- Trial name
- NCT06785090
- Testing
- Bromfenac, Moxifloxacin 0.5% ophthalmic solution, Dexamethasone phosphate 0.1%
- Where
- Iraq
- Volunteers
- 87 people
- Sponsor
- Inas Abd
Macular Edema, Cystoid
Effect of Prophylactic Ketorolac on CME After Cataract Surgery
The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone…
- Trial name
- NCT00335439
- Testing
- ketorolac tromethamine 0.5% (Acular®)
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Queen's University
Epiretinal Membrane, Pseudophakic Cystoid Macular Edema
"Cataract Surgery in Eyes With Epiretinal Membrane"
The purpose of the study is to evaluate retinal thickness change and the occurrence of central structural retinal changes after uneventful small-incision cataract surgery in eyes with asymptomatic early stages of epiretinal…
- Conditions
- Epiretinal Membrane, Pseudophakic Cystoid Macular Edema, Irvine-Gass Syndrome, Cataract
- Trial name
- NCT03404323
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna
Cystoid Macular Edema
Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility…
- Trial name
- NCT00494494
- Testing
- Standard Care, nepafenac
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of North Carolina, Chapel Hill
Irvine-Gass Syndrome
Treatment of Macular Edema After Cataract Surgery with Subconjunctival Aflibercept
This research study is being conducted to determine the safety and tolerability of subconjunctival injections of aflibercept in the treatment of pseudophakic cystoid macular edema that has not responded well to first-line…
- Trial name
- ACME (NCT03396861)
- Testing
- Aflibercept
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Tufts Medical Center
Cystoid Macular Edema, Cataract
PRevention of Macular EDema After Cataract Surgery
Cystoid macular edema (CME) is a common cause of vision loss after cataract surgery. In the last few years, several new treatments have been tried to address the problem of CME after cataract surgery in diabetic and non-diabetic…
- Conditions
- Cystoid Macular Edema, Cataract, Diabetes Mellitus
- Trial name
- PREMED (NCT01774474)
- Testing
- Bromfenac, Dexamethasone, Bevacizumab
- Where
- 16 sites in Austria, Belgium and 5 more
- Volunteers
- 1,127 people
- Sponsor
- Maastricht University Medical Center
Pseudophakic Cystoid Macular Edema,, Diabetic Macular Edema
Ozurdex for Combined Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema After Cataract Surgery
The purpose of the study is to determine where a sustained steroid delivery system (Ozurdex,Allergan) is safe and effective to treat Cystoid Macular Edema in diabetic patients after Cataract Surgery
- Trial name
- NCT01284478
- Testing
- Dexamethasone Implant
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Northern California Retina Vitreous Associates
Cystoid Macular Edema
Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in Diabetics
This research is being conducted to look at the effects of an intraocular drug (pegaptanib, also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that often occurs…
- Trial name
- NCT00346983
- Testing
- Pegaptanib sodium, Control
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Corneal Edema, Corneal Defect
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
- Conditions
- Corneal Edema, Corneal Defect, Anterior Chamber Inflammation, Ocular Pain
- Trial name
- NCT05626478
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp, Prolensa 0.07% Ophthalmic Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nicole Fram M.D.
Cystoid Macular Edema Following Cataract Surgery
PCME Prevention in Patients With NPDR
Pseudophakic cystoid macular edema (PCME), or Irvine-Gass syndrome, is retinal thickening of the macula, which usually develops within 3 months after surgery, with a peak incidence between 4 and 6 weeks.
- Trial name
- NCT04940338
- Testing
- Bromfenac Ophthalmic 0.09% Ophthalmic Solution, Dexamethasone Ophthalmic, Phacoemulsification surgery (PHACO)
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Cataract, Glaucoma
Incidence of Sub-clinical Cystoid Macular Edema After Cataract Surgery
Cystoid macular edema (CME) can limit visual acuity after cataract surgery. Little is known whether the incidence is similar between standard ultrasound phacoemulsification cataract surgery (phaco), femtolaser assisted cataract…
- Trial name
- ICCME (NCT04161963)
- Testing
- SD-OCT, OCT-A
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Cystoid Macular Edema Following Cataract Surgery
CME With Different Fluidic Parameters
Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on…
- Trial name
- NCT01385852
- Testing
- microcoaxial phacoemulsification
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Open Angle Glaucoma and Cataract
RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.
Post-operative cystoid macular oedema (CMO) is a common complication causing visual loss following routine cataract surgery. This complication is more prevalent in eyes with excessive inflammation as they heal from surgery.
- Trial name
- CMO (NCT03292796)
- Testing
- Prostaglandins
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Julie Dawson
Postoperative Cystoid Macular Edema, Irvine-Gass Syndrome
Study for Optimizing Anti-inflammatory Prophylaxis
The purpose of this study is to investigate which anti-inflammatory treatment is best at preventing postoperative inflammation following cataract surgery.
- Trial name
- SOAP (NCT03383328)
- Testing
- NSAID + prednisolone, preoperative, NSAID + prednisolone, postoperative, NSAID, preoperative
- Where
- Denmark
- Volunteers
- 470 people
- Sponsor
- Line Kessel
Macular Edema
A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients
The purpose of this study is to determine whether nepafenac is safe and effective for reducing the incidence of macular edema following cataract surgery in diabetic retinopathy patients.
- Trial name
- NCT00782717
- Testing
- Nepafenac ophthalmic suspension, 0.1% (NEVANAC), Nepafenac ophthalmic suspension vehicle, Prednisolone acetate ophthalmic suspension (OMNIPRED)
- Volunteers
- 263 people
- Sponsor
- Alcon Research
Macular Edema, Cystoid, Vision Disorders
Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema
This study is undertaken to determine the effect of intravitreal long acting dexamethasone implant, (Ozurdex®) in improving outcome of cataract surgery in patients with diabetic macular edema.
- Conditions
- Macular Edema, Cystoid, Vision Disorders, Diabetic Macular Edema, Cystoid Macular Edema Following Cataract Surgery
- Trial name
- NCT01546402
- Testing
- Dexamethasone Drug delivery system (Ozurdex), Cataract surgery
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh