Clinical trials: DEGLUTİTİON
Gastroesophageal Reflux
An Assessment of pH Testing Methods
Gastroesophageal reflux disease (GERD) is a common and potentially debilitating disorder. Typical symptoms include heartburn and regurgitation of acid tasting substances.
- Trial name
- NCT01364610
- Testing
- Bravo, Standard Care
- Where
- 2 sites in Canada
- Volunteers
- 86 people
- Sponsor
- University of Calgary
Dysphagia
Specialize Dysphagia Training and Knowledge/Competency of Nurses
The aim of this research is to determine the effect of specialized dysphagia training on knowledge and competency of nurses.
- Trial name
- NCT05626361
- Testing
- Dysphagia training, Reading material
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cervical Pain, Posterior, Swallowing Difficulties
Tongue Pressure in Middle-Aged and Elderly Individuals With Chronic Cervical Pain
The goal of the cross-sectional study is to explore the impact of neck pain on tongue pressure in the middle-aged and elderly population and analyze the effects of different cranio-cervical positioning on tongue pressure…
- Conditions
- Cervical Pain, Posterior, Swallowing Difficulties, Swallowing Disorders
- Trial name
- NCT07021586
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
GERD (Gastroesophageal Reflux Disease)
National Survey on GERD Patients (Adults and Children)
To describe GERD digestive expression according to ages: - children (from 0 to 23 months) and (24 months and more)- adults (from 18 to 29 years old), (from 30 to 39 years old), (from 40 to 49 years old), (from 50 to 59 years…
- Trial name
- RGO à trav (NCT00833573)
- Where
- 1,053 sites in France
- Volunteers
- 4,400 people
- Sponsor
- AstraZeneca
Proton Pump Inhibitors, Human Gastrointestinal Tract
Intestinal Microbiota After PPI Treatment
This clinical study aims to investigate the effects of short-term treatment with proton pump inhibitors (PPIs) on the gut microbiota of pediatric patients.
- Conditions
- Proton Pump Inhibitors, Human Gastrointestinal Tract, Gastroesophageal Reflux Disease
- Trial name
- PPI (NCT07036627)
- Testing
- study of microbiota
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Gastroesophageal Reflux, Nervous System Diseases
Comparative Anti-Reflux Procedures in Neurologically Impaired Children
This trial is a randomized controlled trial of two standard anti-reflux procedures, Nissen fundoplication versus gastrojejunal feeding tubes (GJ tubes), in children and adolescents with functional and intellectual impairment who…
- Conditions
- Gastroesophageal Reflux, Nervous System Diseases, Fundoplication, Enteral Nutrition
- Trial name
- CARPNIC (NCT01307982)
- Testing
- Fundoplication, Gastrojejunal (GJ) feeding tube
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Gastroesophageal Reflux Disease, Gastro-oesophageal Reflux
Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease.
The purpose of this observational study (this means that no drug is being tested in this study) is to obtain updated and detailed information about the Gastroesophageal Reflux Disease (GERD) specificities in European patients.
- Conditions
- Gastroesophageal Reflux Disease, Gastro-oesophageal Reflux, Gastro-Esophageal Reflux, Esophageal Reflux
- Trial name
- PROFILE (NCT01601379)
- Volunteers
- 7,964 people
- Sponsor
- Janssen-Cilag International NV
Pressure Injury, Dysphonia
Initial Increase in Cuff Pressure in Anterior Cervical Spinal Surgery
When the retractor blades oped and is positioned to provide the surgical access in the anterior cervical spine surgery, it cause the trachea to deviate laterally and pose pressure on the tissue between the retractor and the…
- Conditions
- Pressure Injury, Dysphonia, Dysphagia
- Trial name
- NCT03240042
- Testing
- nasotracheal intubation, orotracheal intubation
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Prevention, Rehabilitation
Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions
The research is about a prospective study conducted in patients suffering from dysphagia and cervical spine disorders and how they are interrelated.
- Trial name
- DysphagCerv (NCT01418105)
- Testing
- Videofluroscopic swallow study (VFSS), cervical spine isometric exercises, Fiberoptic endoscopic esophageal study (FEES)
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Oral Dryness and Saliva Altered, Oral Manifestations
The Effects of Using Augmented Reality (AR) System to Train Foreign Care Workers.
The aim of this study was to evaluate the effect of augmented reality (AR) system training intervention of foreign care workers on the salivary biomarker and oral function of older people.
- Conditions
- Oral Dryness and Saliva Altered, Oral Manifestations, Swallowing Disorder
- Trial name
- NCT05938166
- Testing
- oral care augmented reality (AR), video-based oral hygiene education course
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Achalasia Cardia, GERD-HRQL Scale
Compare the Quality of Life of Patients With Achalasia Cardia (AC) After Laparoscopic and Open Esophagocardiomyotomy.
Study design. A randomized, prospective design study with retrospective data addition was conducted at two medical institutions between December 2017 and July 2025.
- Conditions
- Achalasia Cardia, GERD-HRQL Scale, Eckardt Scale
- Trial name
- GERD-HRQL (NCT07177222)
- Testing
- laparoscopic esophagocardiomyotomy, open surgery
- Where
- Kyrgyzstan
- Volunteers
- 38 people
- Sponsor
- Osh State University
Dysphagia
Comparison of Traditional Dysphagia Therapy and Developed Protocol for Dysphagia Patients in Intensive Care Unit
Dysphagia (swallowing disorders) in intensive care unit (ICU) patients is associated with poor outcomes, including aspiration pneumonia, prolonged hospitalization, and increased mortality.
- Trial name
- NCT07005427
- Testing
- dysphagia therapy, Designed protocol for dysphagia
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Gastroesophageal Reflux Disease
Antireflux Ablation Therapy (ARAT) Vs Antireflux Mucosectomy (ARMS) In The Management Of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease has a high global prevalence, proton pump inhibitors are the cornerstone in the management but 10-20% of the patients are refractory to these, surgical treatment being an option of treatment in…
- Trial name
- NCT04036942
- Testing
- Ablation of the gastroesophageal junction with hybrid argon plasma, mucosectomy with band of the gastroesophageal junction
- Where
- Mexico
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Oral Cavity Cancer, Dysphagia
Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment
While the group of oral cavity cancer (OCC) survivors continue to increase, surgeons and oncologist intensify their search for improved treatment and rehabilitation methods to reduce the morbidity of management without…
- Conditions
- Oral Cavity Cancer, Dysphagia, Quality of Life
- Trial name
- NCT06407570
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Weight Loss, Adverse Events
The IGBallon (R) - for Use in the Treatment of Obesity
This study is a prospective, non-randomized, open-label, single-center study. The aim of this study is to assess the safety of the IGballoon in the human body.
- Conditions
- Weight Loss, Adverse Events, Comorbidities
- Trial name
- IGBallon (NCT07647991)
- Testing
- IGBalloon
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Medical University of Vienna
Gastroesophageal Reflux Disease
Nursing Teaching Scheme for Patients With Gastroesophageal Reflux Disease
The aims of the study are: Assess patient's level of knowledge regarding gastroesophageal reflux disease. Assess patient' compliance and symptoms of gastroesophageal reflux disease.
- Trial name
- NCT05937204
- Testing
- Nursing Teaching
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Psychotic Disorders, Gastroesophageal Reflux
Study of the Effects of Pantoprazole on Levels of Prescribed Psychiatric Medications
The purpose of this 9-day study is to determine if: 1. Pantoprazole modifies the steady-state plasma concentrations of orally administered psychotropic medications including valproic acid, lithium, and second-generation…
- Trial name
- PK-PPI (NCT02213887)
- Testing
- Pantoprazole
- Where
- Canada
- Sponsor
- University of British Columbia
Multiple System Atrophy, Parkinson Disease
Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders.
- Conditions
- Multiple System Atrophy, Parkinson Disease, Progressive Supranuclear Palsy, Motor Neuron Disease
- Trial name
- FEEMSA (NCT04706234)
- Where
- 16 sites in Austria, Germany and 6 more
- Volunteers
- 350 people
- Sponsor
- Kliniken Beelitz GmbH
GERD
Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs
This study was a multicentre, double-blind, randomised, placebo-controlled parallel group study consisting of 4 visits over a period of 6 months.
- Trial name
- NCT00241514
- Testing
- Esomeprazole
- Where
- 113 sites in United States, Belgium and 4 more
- Volunteers
- 334 people
- Sponsor
- AstraZeneca
Gastroesophageal Reflux
SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01)
The aim of this study is to evaluate the efficacy of a new thickened formula on regurgitation
- Trial name
- SWAN (NCT02710955)
- Testing
- Thickened infant formula
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- United Pharmaceuticals
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