Clinical trials: DEGLUTİTİON
Systemic Sclerosis, Gastroesophageal Reflux
Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis
Proton pump inhibitor (PPI) twice daily dosing regimen-a standard dose therapy for gastroesophageal reflux disease (GERD)-is an effective therapy for uncomplicated GERD in systemic sclerosis (SSc) but there is no data of response…
- Conditions
- Systemic Sclerosis, Gastroesophageal Reflux, Proton Pubm Inhibitor
- Trial name
- NCT03561233
- Testing
- Omeprazole 20mg
- Volunteers
- 250 people
- Sponsor
- Khon Kaen University
Gastroesophageal Reflux Disease (GERD)
Safety and Efficacy the Medigus SRS Endoscopic Stapling System in Gastroesophageal Reflux Disease (GERD)
The study is designed to test the safety and efficacy of the Medigus SRS endoscopic stapling system for the treatment of GERD. The system allows the operator to staple the stomach to the esophagus,in order to restore the…
- Trial name
- NCT00734747
- Testing
- Medigus SRS endoscopic stapling system
- Where
- 6 sites in United States, Austria and 3 more
- Volunteers
- 72 people
- Sponsor
- Aviel Roy-Shapira, M.D.
Barrett's Esophagus, Gastroesophageal Reflux Disease (GERD)
Epidemiology of Barrett's Esophagus: A Population Based Study
To assess attitudes toward screening for esophageal adenocarcinoma (EAC) and Barrett's esophagus (BE) in the community. To develop a population based clinical risk factor prediction model for the diagnosis of BE and identify…
- Conditions
- Barrett's Esophagus, Gastroesophageal Reflux Disease (GERD), Olmsted County Resident
- Trial name
- NCT01286155
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease
Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets
It is planned to compare the efficacy and safety of rabeprazole 50 mg DDR (dual delayed release) capsules versus rabeprazole 20 mg enteric coated tablets administered once daily in patients with Gastroesophageal Reflux Disease…
- Trial name
- NCT03037606
- Testing
- Rabelis DDR 50 mg Capsules, Pariet 20 mg Enteric Coated Tablets
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Oropharyngeal Cancer
Assessment of Swallowing Function and Quality of Life in Oropharyngeal Cancer Patients Treated by Chemo-radiotherapy
Open-label, interventional, multicentric, randomized, phase III study. Cancer studied is the oropharyngeal cancer. Study is composed by 2 arms of subjects: prophylactic or reactive percutaneous endoscopic gastrostomy tube…
- Trial name
- SwallPEG (NCT04019548)
- Testing
- Percutaneous Endoscopic Gastrotomy tube placement, Cisplatin injection, Radiotherapy
- Where
- 2 sites in Belgium
- Volunteers
- 110 people
- Sponsor
- Jules Bordet Institute
Pulmonary Aspiration, Gastric Content Aspiration
Ultrasound Assessment of Gastric Volume in Diabetic Versus Non-Diabetic Term Pregnant Women Undergoing Cesarean Section
The aim of the work to compare estimated gastric volumes through ultrasound in fasting diabetic and non-diabetic pregnant women scheduled for caesarean section.
- Trial name
- NCT06621706
- Testing
- Gastric ultrasonography
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
GERD (Gastroesophageal Reflux Disease)
Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) Symptoms
The purpose of this research is to evaluate the safety and effectiveness of the eGERD device, which is a novel device for treating Gastroesophageal Reflux Disease (GERD). The main questions this research aims to answer are: 1.
- Trial name
- NCT06613438
- Testing
- eGERD device
- Where
- 5 sites in United States, Israel
- Volunteers
- 84 people
- Sponsor
- Gerd Care Medical Ltd
GERD (Gastroesophageal Reflux Disease)
Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare
Adherence to GERD treatment, including medication, diet, and lifestyle, is essential for symptom control and complication prevention, yet adherence rates remain low due to various demographic and clinical factors.
- Trial name
- AppGERD (NCT07125521)
- Testing
- GERCCare mobile app
- Where
- Vietnam
- Volunteers
- 380 people
- Sponsor
- Institute of Gastroenterology and Hepatology, Vietnam
Cough, Asthma
Validation of the C-mo System - Cough Monitoring
The goal of this clinical study is to validate C-mo System's ability to automatically detect and characterise cough, in patients over 2 years old with cough as a key or refractory symptom.
- Conditions
- Cough, Asthma, Chronic Obstructive Pulmonary Disease, Gastro Esophageal Reflux
- Trial name
- C-mo_01 (NCT05989698)
- Testing
- C-mo System
- Where
- 8 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Cough Monitoring Medical Solutions
Gastroesophageal Reflux Disease
Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD.
A prospective multi center case controlled trial on the clinical feasibility of a new full thickness endoscopic plication device for patients with GERD.
- Trial name
- NCT01798212
- Testing
- endoscopic full thickness plication
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Krankenhaus Barmherzige Schwestern Linz
Deglutition Disorder
Voice Analysis Using the LPC (Linear Predictive Coding)Method for the Prediction of Aspiration
It was well known that aspiration is the primary cause of an aspiration pneumonia among the dysphagia patients. In order to predict the degree of an aspitation,video-fluoroscopic-swallowing study and fiberoptic-endoscopic…
- Trial name
- NCT01981239
- Testing
- VFSS
- Where
- South Korea
- Sponsor
- Ulsan University Hospital
Dyspepsia, Gastroesophageal Refluxdisease
Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice
The primary purpose of the study is to determine the effect of esomeprazole compared to placebo in patients from general practice who have previously been treated with proton-pump-inhibitors (PPI) and who have no upper endoscopic…
- Conditions
- Dyspepsia, Gastroesophageal Refluxdisease, Ulcer
- Trial name
- NCT00363701
- Testing
- esomeprazole
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Barrett Esophagus
Novel Method of Surveillance in Barrett's Esophagus
This study is being done to see how biomarkers (abnormalities in molecules of cells ) present in their Barrett's esophagus agree with results from surveillance biopsies; and to compare three different brush devices used to…
- Trial name
- NCT00955019
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux
A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis
The purpose of this study is to evaluate whether Rebamipide facilitate the healing of inflamed mucosa as an adjuvant regimen in erosive reflux esophagitis (ERE).
- Trial name
- REPAIR (NCT02755753)
- Testing
- Lansoprazole, Rebamipide
- Where
- 5 sites in China, South Korea
- Volunteers
- 143 people
- Sponsor
- YongChan Lee
Eosinophilic Esophagitis (EoE)
Surface EMG Testing on Swallowing in EoE Patients
Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis
- Trial name
- sEMG (NCT07156357)
- Testing
- Surface Electromyography, Fiberoptic Endoscopic Evaluation of Swallowing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dysphagia
Role of Health Education in the Semipresential Logopedic Treatment of the Patient With Oropharyngeal Dysphagia
When reviewing the literature, the need to investigate the health education of patients with dysphagia and their family members / caregivers has been detected.
- Trial name
- EDU-DIS (NCT04959877)
- Testing
- health education
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the relative merits, safety and effectiveness of transoral incisionless fundoplication (TIF) in proton pump inhibitor (PPI) dependent GERD patients compared with sham procedure.
- Trial name
- NCT01110811
- Testing
- Transoral Incisionless Fundoplication (TIF)
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 60 people
- Sponsor
- EndoGastric Solutions
Post-stroke Dysphagia, Oropharyngeal Dysphagia (OPD)
Motor Imagery in Post-Stroke Dysphagia
This study evaluated the effects of motor imagery added to conventional swallowing rehabilitation in patients with dysphagia after stroke.
- Trial name
- MI-PSD (NCT07656844)
- Testing
- Video-Assisted Motor Imagery, Motor Imagery Training, Conventional Dysphagia Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara Etlik City Hospital
Gastro-esophageal Reflux Disease (GERD)
HRIM vs Mucosal Impedance in GERD Participants
Does baseline impedance measured during the landmark phase of esophageal High resolution impedance manometry HRIM correlates with direct mucosal impedance measurement and discriminates GERD from non GERD patients?
- Trial name
- NCT02812407
- Testing
- Mucosal Impedance
- Where
- United States
- Sponsor
- Mayo Clinic
Stomach Neoplasms, Esophageal Neoplasms
Impact of Gastric Tube Reconstruction Widths on Quality of Life for Esophagogastric Cancers
The incidence of cancer of the esophagogastric junction has rapidly risen in recent three decades, and surgery still remains the optimum therapy.
- Trial name
- NCT01911832
- Testing
- esophagojejunostomy after total gastrectomy, Roux-en-Y gastrojejunostomy after subtotal gastrectomy, wide tube reconstruction after subtotal gastrectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
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