Clinical trials: DM
Atherosclerosis
The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients
Diabetes is a highly atherogenic disease. Pomegranate juice has impressive antioxidant properties. It has been proven to decrease oxidant stress and to cause the regression of atherosclerotic plaques in hypercholestrolemic and…
- Trial name
- POMX (NCT00470808)
- Testing
- POMx
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel
PreDiabetes, Diabetes Mellitus, Type 2
Chronotype, Chrononutrition and Glucose Tolerance Among Prediabetic Individuals
Chronotype and chrononutrition, both are emerging research fields in nutritional epidemiology. However, its association with glycemic control in the global population is less clear.
- Trial name
- NCT05163964
- Testing
- Lifestyle Intervention
- Where
- 11 sites in Malaysia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Diabetes Mellitus, Atherosclerosis
Aliskiren's Effect on Arterial Stiffness and Platelet Function in Patients With Diabetes Mellitus (DM)
Aliskiren is a novel renin inhibitor approved for the treatment of hypertension. The effect of aliskiren on arterial stiffness, inflammation and oxidative stress has not been fully investigated yet.The aim of this study is to…
- Trial name
- NCT00732407
- Testing
- aliskiren, losartan
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Diabetes Mellitus, Type 2
Effect of Nicorandil in Type 2 Diabetic Obese Patients
1. Evaluating the effect of nicorandil on glycemic control of diabetic obese patients treated with sulfonylureas. 2. Investigating the effect of nicorandil on body weight of diabetic obese patients treated with sulfonylureas.
- Trial name
- NCT06423729
- Testing
- Nicorandil 10 MG
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Tanta University
Diabetes Mellitus, Type 2
Evaluation of the Prandial Treatment Adjustment Effect Via Continuous Glucose Monitoring on Type 2 Diabetes Mellitus (DM) Patients Uncontrolled With a Basal Insulin or Premix Once a Day
Primary Objective: To evaluate the effect of prandial treatment adjustment, based on continuous blood glucose monitoring, on glucose control in type 2 diabetes patients who are not controlled by treatment with once daily basal…
- Trial name
- SeLan (NCT01234597)
- Testing
- INSULIN GLARGINE (HOE901), INSULIN GLULISINE (HMR1964)
- Where
- 11 sites in Israel
- Volunteers
- 219 people
- Sponsor
- Sanofi
Postural Balance, Fall Risk
Additional Effects of Proprioceptive Neuromuscular Facilitation With Otago Exercises on Fall Risk in Diabetes Mellitus Patients
Diabetes Mellitus is considered as one of the most prevalent issues among global population and 50% of all the diabetic patients particularly diabetes type II develop peripheral neuropathy.
- Conditions
- Postural Balance, Fall Risk, Diabetes (DM), Fear of Falling
- Trial name
- NCT07122726
- Testing
- Otago and PNF exercise, Otago Exercise
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Myotonic Dystrophy, Facioscapulohumeral Muscular Dystrophy
Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are inherited disorders characterized by progressive muscle weakness and loss of muscle tissue.
- Conditions
- Myotonic Dystrophy, Facioscapulohumeral Muscular Dystrophy, Muscular Dystrophy, Myotonic Dystrophy Type 1
- Trial name
- NCT00082108
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Impaired Glucose Tolerance, Peripheral Polyneuropathy
Electrodiagnostic Parameters in Patients With Impaired Glucose Tolerance and Diabetes Mellitus
The purpose of this study is to evaluate the distal sensory nerves of the feet, namely, the dorsal sural, medial dorsal cutaneous and medial plantar nerves, in patients with impaired glucose tolerance and diabetes mellitus type 2…
- Conditions
- Impaired Glucose Tolerance, Peripheral Polyneuropathy, DM
- Trial name
- NCT01094418
- Testing
- Nerve conduction studies ( NCS) of the peripheral nerves
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Diabetes Mellitus, Type 2
Self-Care for Older People With Diabetes Mellitus
In Singapore, the prevalence of diabetes was approximately 12.8% in 2014 and was projected to rise to 22.7% in 2035. In 2015, the International Diabetes Federation (IDF) reported that Singapore has the second highest proportion…
- Trial name
- SCOPE-DM (NCT03890991)
- Testing
- SCOPE-DM, SCOPE-DM with 3 months' supply of glucometer, SCOPE-DM with 6 months' supply of glucometer
- Where
- Singapore
- Volunteers
- 320 people
- Sponsor
- National University of Singapore
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes Mellitus (DM)
Proteome-Wide Association and LLM-Based Prioritization of Type 2 Diabetes Protein Targets
Type 2 diabetes is a common condition in which the body has difficulty controlling blood sugar. This study will use existing genetic, protein, and health data from prior research studies to identify blood proteins that may play a…
- Trial name
- LAUNCH-T2D (NCT07832656)
- Volunteers
- 31,994 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Type 2 Diabetes Mellitus
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome
The purpose of this study is to determine whether an increase in lipid bodies in leukocytes will lead to an increase in eicosanoid production.
- Trial name
- NCT02498119
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diabetes
SUPREME-DM (Diabetes Mellitis) Treatment Study
This multisite pragmatic clinical trial was designed to assess the effectiveness of a single scripted telephone call to diabetes patients who (a) were currently above recommended clinical goals for glucose, blood pressure, or…
- Trial name
- NCT02192255
- Testing
- Intervention Phone Call
- Where
- United States
- Volunteers
- 2,378 people
- Sponsor
- HealthPartners Institute
Insulin Dependent Diabetes, Diabetes (DM)
Integrating New Skills Into Diabetes Education With CGM
This study is designed to test the preliminary efficacy of a three-stage continuous glucose monitor (CGM) integration program for older adults who are taking insulin.
- Conditions
- Insulin Dependent Diabetes, Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2), Diabetes Education
- Trial name
- INSIDE-CGM (NCT07463209)
- Testing
- Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of North Carolina, Chapel Hill
Type 2 Diabetes
Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors With T2DM
The objective of this protocol is to evaluate the efficacy and cost-effectiveness of 8 sessions of in-home, telephone-delivered, culturally-modified, manualized diabetes-modified, behavioral activation treatment (Home DM-BAT)…
- Trial name
- HOME DM-BAT (NCT04203147)
- Testing
- Supportive Therapy (Control), Home DM-BAT
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- State University of New York at Buffalo
Type 2 DM /Diabetic Nephropathy
CRP to Serum Albumin Ratio in Type 2 DM é Diabetic Nephropathy
we aimed to compare C-reactive protein to serum albumin ( CAR) level of the T2DM patients with DN to those T2DM without DN
- Trial name
- NCT05681286
- Volunteers
- 70 people
- Sponsor
- Assiut University
DIABETES EDUCATION
The Effect of Kamishibai Diabetes Education on Knowledge, HbA1c, and Quality of Life in Children
Children diagnosed with Type 1 Diabetes Mellitus (T1DM) initially receive intensive education with their families. Studies indicate that over time, this initial education becomes routine, reducing its effectiveness and failing to…
- Trial name
- NCT06535672
- Testing
- kamishibai education, routine education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Okan University
Diabetes (DM), Retinopathy, Diabetic
Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy
This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR).
- Conditions
- Diabetes (DM), Retinopathy, Diabetic, Diabetic Retinopathy (DR), Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus
- Trial name
- NCT07351786
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sara A Belal
Acute Ischemic Stroke, Diabetes (DM)
CGM in Acute Ischemic Stroke
The goal of this randomized clinical trial is to evaluate whether continuous glucose monitoring (CGM) can be used to guide glucose management in patients with type 2 diabetes who are admitted with an acute ischemic stroke and…
- Conditions
- Acute Ischemic Stroke, Diabetes (DM), Diabetes Type 2, Hyperglycemia
- Trial name
- SENSTROKE (NCT07510919)
- Testing
- Continuous Glucose Monitoring, Point-of-Care Testing
- Volunteers
- 82 people
- Sponsor
- Isala
Type 2 Diabetes Mellitus
Placebo Controlled, Dose Escalation Study in Subjects With Type 2 Diabetes Mellitus Being Treated With Sulfonylurea
The purpose of this study is to provide an initial assessment of the safety, tolerability and efficacy of ISIS 113715 in combination with sulfonylurea in type 2 diabetes subjects.
- Trial name
- NCT00455598
- Testing
- ISIS 113715
- Where
- 39 sites in Poland, Romania and 1 more
- Volunteers
- 88 people
- Sponsor
- Ionis Pharmaceuticals, Inc.