Clinical trials: DM
Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM)
RCT Glargine vs NPH for Treatment of DM in Pregnancy
We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy.
- Conditions
- Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus, Class A2
- Trial name
- NCT06619301
- Testing
- Insulin glargine, insulin NPH
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Loyola University
Type II Diabetes
SOKARY Mobile Application With Type II Diabetes
Android mobile application named (SOKARY)
- Trial name
- DM (NCT04843592)
- Testing
- SOKARY Mobile
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Magda Bayoumi
Type 2 Diabetes Mellitus
Effect of Internet Therapeutic Intervention on A1C Levels in Type 2 Diabetes Mellitus (DM) on Combination Oral Therapy
This project will test the effectiveness of an Internet based glucose monitoring system on the A1C levels of patients with type 2 diabetes.
- Trial name
- NCT01060241
- Testing
- Internet Intervention
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Endocrine Research Society
Diabetes Mellitus, Type 2
Lifestyle Intervention For Effective Diabetes Management
Chronic disease management programs are shown to reduce mortality, recurrent hospitalizations, and improve indirect societal costs among specific subgroups of the population.
- Trial name
- LIFE-DM (NCT00813930)
- Testing
- INTERxVENT lifestyle modification program
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Diabetes Mellitus, Type 1
SAM - Skip a Meal - Insulin Glargine, Diabetes Mellitus Type 1
Primary objective: To compare metabolic control as measured by Blood Glucose (BG) upon arising from bed (7:00 am - 12:00 pm) in type 1 Diabetes mellitus patients who skip the morning meal during treatment with MDI basal/bolus…
- Trial name
- NCT00313937
- Testing
- Insulin glargine
- Where
- Germany
- Volunteers
- 91 people
- Sponsor
- Sanofi
Diabetes Mellitus, Type 2
Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
To compare the efficacy of ORMD-0801 to placebo in improving glycemic control as assessed by A1C in inadequately controlled T2DM subjects on diet control alone or on diet control and metformin monotherapy or two or three oral…
- Trial name
- NCT04817215
- Testing
- ORMD-0801
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM)
Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.
The goal of this clinical trial is to develop and evaluate a novel diabetes ketoacidosis risk mitigation strategy to support the safe use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) therapy in participants with type 1…
- Conditions
- Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM), Chronic Kidney Disease, Diabetic Ketoacidosis
- Trial name
- SCOUT-CKD (NCT07325201)
- Testing
- Sotagliflozin initiation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- HealthPartners Institute
Total Hip Arthroplasty, Survival, Prosthesis
Multicenter Mpact DM France
The primary objective of the study is to evaluate the 10-year performance of the MPACT DM cup in the treatment of patients requiring total hip arthroplasty.
- Trial name
- NCT05818891
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Medacta International SA
Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP)
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
This Phase 1b basket trial will investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity and preliminary efficacy of RAY121, a inhibitor of classical complement pathway, after multiple dose…
- Conditions
- Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM)
- Trial name
- NCT06371417
- Testing
- RAY121
- Where
- 77 sites in United States, Australia and 18 more
- Volunteers
- 144 people
- Sponsor
- Chugai Pharmaceutical
Type 2 Diabetes
Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)
The objective of this protocol is to answer the questions: 1) Within food supplementation options, are mailed stock boxes superior to food vouchers in terms of achieving glycemic control? 2) Is the combination of mailed stock…
- Trial name
- LIFT-DM (NCT04181424)
- Testing
- Diabetes Education Plus Monthly Food Vouchers, Diabetes Education Plus Combination of Monthly Food Vouchers and Stock Boxes, Diabetes Education Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- State University of New York at Buffalo
Hypercholesterolemia
Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)
An efficacy and safety study of ezetimibe (+) simvastatin compared to atorvastatin at week 6 in diabetics or metabolic syndrome patients in Korea.
- Trial name
- NCT00157924
- Testing
- simvastatin (+) ezetimibe, atorvastatin
- Volunteers
- 190 people
- Sponsor
- Organon and Co
Amputation
Clinical Evaluation of Direct Manufactured Prosthetic Sockets
The purpose of this study is to evaluate a new prosthetic socket construction technique in order to improve the quality of care to lower extremity amputees.
- Trial name
- NCT01155024
- Testing
- Traditional fabricated prosthetic socket, Direct manufactured (DM) prosthetic socket
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio Willow Wood
Primary Brain Tumors, Metastatic Malignant Neoplasm to Brain
Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors
DM-CHOC-PEN is a polychlorinated pyridine cholesteryl carbonate that has demonstrated antineoplastic activities in patients with advanced cancers - melanoma, lung, breast and glioblastoma multiforme (GBM) involving the CNS during…
- Trial name
- DM-CHOC-PEN (NCT02038218)
- Testing
- 4-Demethyl-4-cholestryloxycarbonylpenclomedine
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- DEKK-TEC, Inc.
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease, Type 2 Diabetes
Interactive Tool to Support Self-management Through Lifestyle Feedback, Aimed at Physical Activity of COPD/DM Patients
Rationale: Physical activity is an important factor for a healthy lifestyle. Although physical activity can delay complications and decrease the burden of the disease in chronically ill persons, their level of activity is often…
- Trial name
- RCTIt'sLiFe! (NCT01867970)
- Testing
- Tool, Self-management Support Program
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Maastricht University Medical Center
Type 1 Diabetes
Hypoglycemia Associated Autonomic Failure in Type 1 DM
It is unclear what effect selective serotonin reuptake inhibitors (SSRIs) have on hypoglycemia. Thus, the American Hospital Formulary Service recommends careful monitoring of blood glucose levels in all patients with diabetes…
- Trial name
- NCT00592670
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Diabetes Mellitus (DM), Dyslipidemia
Impact of Golden Rice-Piper Crocatum Cookies on Lipid Control in Diabetes Mellitus Patients
People with diabetes often experience abnormal blood fat levels, known as dyslipidemia, which increase the risk of heart disease and stroke.
- Conditions
- Diabetes Mellitus (DM), Dyslipidemia, Lipid Profile, Functional Food
- Trial name
- GRPC-DM (NCT07268781)
- Testing
- Golden Rice cookies with Piper crocatum Extract
- Where
- 2 sites in Indonesia
- Volunteers
- 102 people
- Sponsor
- Hasanuddin University
Myotonic Dystrophy 1, Myotonic Dystrophy 2
An Ambispective Natural History Study in Myotonic Dystrophy Patients Linking Retrospective Data Captured From the DM-Scope Registry With a Prospective 24-month Follow-up Period
This natural history observational study is being conducted to follow patients with DM1 or DM2 over a 2 year period to study the presence of myotonia, how it's perceived and its impact on patients quality of life.
- Trial name
- Track-DM (NCT07732439)
- Where
- 6 sites in France
- Volunteers
- 100 people
- Sponsor
- Lupin Ltd.
Type 2 Diabetes Mellitus
Effect of Internet Therapeutic Intervention on A1C Levels in Type 2 Diabetes Mellitus (DM)
Management of diabetes is an evolving challenge to health care professionals. The fluctuations of glucose levels over the lifetime of patients with diabetes can lead to complications such as nephropathy, neuropathy, retinopathy…
- Trial name
- NCT00814190
- Testing
- Internet Intervention
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Endocrine Research Society
Diabetes Mellitus, Type 2
Evaluation of the Prandial Treatment Adjustment Effect Via Continuous Glucose Monitoring on Type 2 Diabetes Mellitus (DM) Patients Uncontrolled With a Basal Insulin or Premix Once a Day
Primary Objective: To evaluate the effect of prandial treatment adjustment, based on continuous blood glucose monitoring, on glucose control in type 2 diabetes patients who are not controlled by treatment with once daily basal…
- Trial name
- SeLan (NCT01234597)
- Testing
- INSULIN GLARGINE (HOE901), INSULIN GLULISINE (HMR1964)
- Where
- 11 sites in Israel
- Volunteers
- 219 people
- Sponsor
- Sanofi