Clinical trials: DWI-MRI
Pancreatic Adenocarcinoma
Prospective Evaluation of MRI Biomarkers in Pancreatic Ductal Adenocarcinoma
This is a prospective cohort study in participants with pancreatic adenocarcinoma who are undergoing surgical resection. Participants will have up to two magnetic resonance imaging (MRI) scans with and without intravenous…
- Trial name
- NCT02775786
- Testing
- MRIs with and without intravenous contrast (up to 2)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Columbia University
Metastatic Breast Cancer in the Liver
Dynamic Contrast-enhanced MRI Combined With IVIM-DWI for Early Prediction of Chemosensitivity in Liver MBC
The purpose of this study is to further use DCE-MRI and ivim-dwi to predict the chemotherapy sensitivity of liver metastasis of breast cancer at an early stage, and to predict the treatment response of tumor at an early stage by…
- Trial name
- DreaminLMBC (NCT05550090)
- Testing
- Chemotherapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Cancer Hospital
Brain Tumor, Glioblastoma
Measuring Non-Enhancing Glioblastoma Progression
The goal of this clinical research study is to learn if magnetic resonance imaging with magnetic resonance spectroscopy ("MRI/MRS" scanning) can measure any extra growth in the tumor that does not show up on regular MRI images.
- Trial name
- NCT00777686
- Testing
- MRI/MRS Scan
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center
CO2 Intoxication
MRI Findings of Encephalopathy Associated With Carbon Dioxide (CO2) Intoxication
Carbon dioxide intoxication is a rare condition and only few case reports are found in the literature. There were six patients who suffered from carbon dioxide intoxication in our hospital about two years ago.
- Trial name
- NCT01380210
- Volunteers
- 6 people
- Sponsor
- China Medical University Hospital
Sarcoma
Quantitative Imaging Biomarkers for Sarcoma
Unless a cancer quickly gets smaller with radiation or chemotherapy, the investigators cannot tell if the treatment is working or not.
- Trial name
- NCT02579980
- Testing
- DCE and DWI MRI, Surgery
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Stroke
Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke
WAKE-UP is an investigator initiated European multicenter randomized controlled clinical trial of MRI based thrombolysis in acute stroke patients with unknown time of symptom onset, e.g.
- Trial name
- WAKE-UP (NCT01525290)
- Testing
- Alteplase
- Where
- 7 sites in Belgium, Denmark and 4 more
- Volunteers
- 501 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Sarcoma
Novel Applications for Sarcoma Assessment
This research aims to improve the way of deciding whether a lump in soft tissue such as fat or muscle is a type of cancer called a soft tissue sarcoma, or if it is benign (non-cancerous).
- Trial name
- NASA (NCT06073314)
- Testing
- Quantitative MRI
- Where
- United Kingdom
- Volunteers
- 186 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
End Stage Renal Disease, Renal Transplant Rejection
MRI in Renal Transplantation
Renal transplantation is the optimal method of treatment for end stage kidney disease however median lifespan of a kidney transplant is around 15 years.
- Conditions
- End Stage Renal Disease, Renal Transplant Rejection, Kidney Transplant Failure and Rejection, Chronic Kidney Diseases
- Trial name
- TransRASL (NCT03705091)
- Testing
- Magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Dense Breast Parenchyma, Breast Cancer Detection
DWI Breast MRI in Dense Breast: A Clinical Trial to Assess the Efficacy and Diagnostic Accuracy of Diffusion Weighted Imaging in Dense Breast Tissue
his clinical trial aims to evaluate the efficacy and diagnostic accuracy of Diffusion Weighted Imaging (DWI) in breast MRI for women with dense breast tissue.
- Conditions
- Dense Breast Parenchyma, Breast Cancer Detection, DWI
- Trial name
- DWI-Breast MRI (NCT06836089)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Graziella di Grezia
Glioma, Neoplasms
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques
Contrast-enhanced MRI is the most common way for evaluating neuroepithelial tumor grading and monitoring for tumor recurrence,but the ability to predict tumor behavior remains very limited.In this study, the investigators will…
- Trial name
- NCT02622620
- Volunteers
- 86 people
- Sponsor
- Tang-Du Hospital
Cancer of the Uterine Cervix
Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy
Rationale: The benefit-risk ratio of surgery following concomitant radiochemotherapy and brachytherapy remains to be defined in cervical squamous-cell carcinoma (SCC) treatment.
- Trial name
- ERRICC (NCT01663753)
- Testing
- 18F-FDG-PET
- Where
- 24 sites in France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation
Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy.
- Conditions
- Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation, Endovascular Thrombectomy
- Trial name
- NCT06213870
- Testing
- Surgical criteria
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Tianjin Huanhu Hospital
Head and Neck Cancer
Functional Imaging in HNC Undergoing Chemoradiation
The purpose of the study is to generate a library of functional imaging and anatomical imaging for patients with head and neck cancers for evaluation of new radiotherapy strategies and planning techniques including IMRT.
- Trial name
- NCT00837980
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer
Diffusion-Weighted MRI for Diagnosis of Multifocal, Multicentric Breast Cancer
Detection of multifocal, multicentric breast cancer in patients with breast cancer affects surgical decision. Histology-proven additional cancer foci have been reported to be detected in 21.0% to 63.0% of affected breasts in…
- Trial name
- NCT04656639
- Where
- South Korea
- Volunteers
- 580 people
- Sponsor
- Seoul National University Hospital
Intracerebral Hemorrhage
Prospective Cohort Study of Intracerebral Hemorrhage
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult…
- Trial name
- POSTER (NCT04707105)
- Where
- China
- Volunteers
- 856 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Prostate Cancer Metastatic
Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (MRI) as a Response Biomarker for Metastatic Prostate Cancer
The skeleton is the most frequent organ of distal metastases in prostate cancer, often representing the only site of metastatic disease.
- Trial name
- iPROMET (NCT05078151)
- Testing
- Whole-Body Diffusion Weighted MRI
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Vall d'Hebron Institute of Oncology
Stroke
CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II
To explore the efficacy and safety of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes
- Trial name
- CHABLIS-T II (NCT04516993)
- Testing
- Tenecteplase, The best treatment selected by local doctors(Aspirin, Recombinant Tissue Plasminogen Activator, Urokinase, Thrombectomy)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Huashan Hospital
Lung Neoplasms
Application of Diffusion Weighted MRI Versus CT in Evaluation of the Effect of Treating Lung Cancer
The purpose of this study is to investigate the diagnostic accuracy of ADC value of diffusion weighted MRI in comparison of conventional treatment assessment criteria in evaluation of chemotherapy.
- Trial name
- NCT02320617
- Testing
- Diffusion Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Air Force Military Medical University, China
Kidney Cancer
Rein 3D PRINT MECHANICS
The goal of this innovative project is to evaluate the correspondence between several imaging modalities for characterizing the elasticity of healthy and pathological renal tissue which could help improve the realism of 3D prints…
- Trial name
- Rein3DP-M (NCT06525831)
- Testing
- MR-elastography exam, Ultrasound exam
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux