Clinical trials: Death, Cardiac
Sudden Cardiac Death
A Prospective,Multiple Center,Cohort Study of Prediction Model on Sudden Cardiac Death and Devices Development by Automatic Analysis From 24h Electrocardiogram in China
This study is a prospective, multicenter, cohort study. The study will be completed in three phases. The first phase aims to establish SCD PW marker and PW score scoring system 1.
- Trial name
- PM-SCD CHINA (NCT03485079)
- Where
- China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Jingfeng Wang
HCM - Hypertrophic Cardiomyopathy, Sudden Cardiac Death
Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy
Pilot interventional randomized clinical trial to study the efficacy of left bundle branch pacing in patients with hypertrophic cardiomyopathy after myectomy for the prevention of progression of heart failure, prevent the…
- Conditions
- HCM - Hypertrophic Cardiomyopathy, Sudden Cardiac Death, Left Bundle Branch Pacing, ICD
- Trial name
- LEFTpaceHCM (NCT07372196)
- Testing
- ICD with left bundle branch area pacing (LBBAP), dual-chamber ICD
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Myocardial Infarction, Autonomic Nervous System Diseases
Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction
The majority of deaths after myocardial infarction occurs in patients with preserved left ventricular ejection fraction (>35%) for whom no prophylactic strategies exist.
- Trial name
- SMART-MI (NCT02594488)
- Testing
- Medtronic Reveal LINQ implantable cardiac monitor
- Where
- 32 sites in Austria, Germany
- Volunteers
- 400 people
- Sponsor
- LMU Klinikum
Cardiovascular Diseases, Diabetes
Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)
To determine associations between dietary factors and risk of major chronic diseases and their risk factors
- Conditions
- Cardiovascular Diseases, Diabetes, Metabolic Syndrome, Cancer
- Trial name
- NCT03221127
- Volunteers
- 2,682 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Liver Transplantation, Hepatocellular Carcinoma
Prognosis Analysis of Elderly Donor Liver in Liver Transplantation
Based on the follow-up data of elderly donation after cardiac death(DCD) donor liver transplant recipients from the CLTR, a database and official website for national data gathering.
- Conditions
- Liver Transplantation, Hepatocellular Carcinoma, Survival
- Trial name
- NCT05355662
- Testing
- Age
- Volunteers
- 11,569 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Mitral Valve Prolapse, Ventricular Arrhythmias and Cardiac Arrest
Mitral Valve Prolapse Arrhythmic Risk
Mitral valve prolapse (MVP) is common with a 2-3 % prevalence in the general association and generally associated with a favorable prognosis.
- Trial name
- MVP-Risk (NCT07830888)
- Testing
- Risk prediction model
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Liver Transplant; Complications, Cardiovascular Complication
Cardiovascular Outcomes in Orthotopic Liver Transplanted Patients (COLT Study)
All patients with orthotopic liver transplantation who are evaluated and followed at each participating centers will be recorded in this study. Within this register a characterization of patients and therapy will be done.
- Conditions
- Liver Transplant; Complications, Cardiovascular Complication, Cardiovascular; Attack, Cardiovascular Stroke
- Trial name
- COLT (NCT05895669)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Atrial Fibrillation, Cerebrovascular Accident
Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm
Atrial fibrillation is the most frequently occurring cardiac arrhythmia, with 1.0-1.5 million cases annually. It is a risk factor for congestive heart failure, and stroke, 75,000 cases of the latter occurring annually in patients…
- Conditions
- Atrial Fibrillation, Cerebrovascular Accident, Death, Sudden
- Trial name
- NCT00007605
- Testing
- Amiodarone, Sotalol
- Where
- 28 sites in United States
- Volunteers
- 706 people
- Sponsor
- US Department of Veterans Affairs
Cardiovascular Diseases, Heart Diseases
Epidemiology of Long QTand Asian Sudden Death in Sleep
To conduct a cross-sectional epidemiologic study of the determinants of prolonged heart rate corrected QT interval (QTc) among 300 men and 300 woman in the population with the highest known risk of SUDS: Southeast Asian refugees…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Arrhythmia, Death, Sudden, Cardiac
- Trial name
- NCT00005367
- Sponsor
- Utah State University
Hypertension, Diabetes
Anglo-Scandinavian Cardiac Outcomes Trial: Post Trial Follow-Up Study
ASCOT-10 is a follow-up study of surviving participants in the United Kingdom (UK)arm of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) which was conducted between 2000 and 2005.ASCOT's results showed substantial…
- Conditions
- Hypertension, Diabetes, Death From Cardiovascular Disease, Myocardial Infarction
- Trial name
- ASCOT-10 (NCT01499511)
- Where
- United Kingdom
- Volunteers
- 1,718 people
- Sponsor
- Imperial College London
Non-ischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM)
Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.
Non-ischemic cardiomyopathies (NICM) represent a heterogeneous group of pathologies characterized by absence of obstructive disease of the epicardial coronary vessels and distinct structural and functional changes of the…
- Conditions
- Non-ischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM), Hypertrophic Cardiomyopathy (HCM), Restrictive Cardiomyopathy
- Trial name
- AINICM (NCT06607471)
- Testing
- Support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation, Support treatment, cardiac medical treatment, aetiology-specific treatment
- Where
- Italy
- Volunteers
- 15,000 people
- Sponsor
- Scientific Institute San Raffaele
Ventricular Tachycardia
Creation of a Pace-mapping Atlas on Healthy and Pathological Hearts
Aim of this study is to collect data from pace mapping performed in three groups of patients : patients presenting ventricular tachycardia and infarction history, patients presenting infarction history without presenting…
- Trial name
- ATLAS (NCT03611465)
- Testing
- Pace-mapping, Standard pace-mapping examination
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Central Hospital, Nancy, France
Cardiac Arrest (CA), Sudden Death, Cardiac
Automated Cardiac Arrest Detection and Alerting in Daily Life
Surviving a cardiac arrest that happens outside the hospital depends on quickly recognizing the event and immediately starting CPR.
- Trial name
- DETECT-4b (NCT06692374)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
DCM - Dilated Cardiomyopathy
Observational Study for Patients With Dilated Cardiomyopathy
Observational study on patients with dilated cardiomyopathy aims to investigate the correlation between cardiac fibrosis, as indicated by cardiac magnetic resonance, and the prognosis of patients with dilated cardiomyopathy, and…
- Trial name
- NCT04837612
- Testing
- No intervention nor exposure
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangdong Provincial People's Hospital
Sudden Cardiac Death, Prolonged QTc Interval
Smoking and Ventricular Repolarization
Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization.
- Trial name
- NCT03916341
- Testing
- EC with nicotine, EC without nicotine, control
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Kidney Failure Chronic, Arrhythmias Cardiac
Effects of Marine n-3 Fatty Acids on Heart Rate Variability and Arrhythmias in Patients Receiving Chronic Dialysis
Background: End Stage Renal Disease (ESRD) patients have an extremely high mortality and the leading cause of death is cardiovascular disease which accounts for 50% of all deaths.
- Trial name
- NCT02147977
- Testing
- dietary supplement: n-3 PUFA, olive oil
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Aalborg University Hospital
PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
This Phase 1 dose escalation trial will assess the safety and preliminary efficacy of a single dose intravenous infusion of RP-A601 in high-risk adult patients with PKP2-ACM.
- Trial name
- NCT05885412
- Testing
- RP-A601
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Hemodialysis, Cardiac Arrhythmia
Implantable Loop Recorder in Hemodialysis Patients
The purpose of this study is to use implantable loop recorder (ILR) in patients under chronic hemodialysis to record arrhythmias and conduction disorders and correlate them with hemodialysis parameters.
- Conditions
- Hemodialysis, Cardiac Arrhythmia, Cardiac Death
- Trial name
- RYTHMODIAL (NCT01252823)
- Testing
- Implantation of ILR
- Where
- 9 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Hypertrophic Cardiomyopathy, Acute Coronary Syndrome
Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis
The objective is to determine whether 99Technetium-NC100692 uptake in patients with ACS (MI) can serve as a marker for scar formation as detected by contrast-enhanced MRI during the process of myocardial remodelling after the…
- Trial name
- SCAR (NCT01230918)
- Testing
- 99mTc-NC100692
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Family Palliative and End-of-Life Care for Advanced Heart Failure
Overall objective is to test whether the 5-weekly family home palliative and end-of-life care (FamPALcare) intervention educational and supportive sessions will improve rural home end-of-life and palliative care (EOLPC) for…
- Trial name
- NCT04153890
- Testing
- FamPALcare
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- West Virginia University